Name: Heparin sodium salt
Brand: TargetMol
SKU: T6531
Price: 298 CNY
Availability: InStock
Rating: 5 (10 reviews)

Heparin sodium salt

很棒

产品编号 T6531Cas号 9041-08-1

别名 肝素钠, Sodium heparinate, Heparin sodium

Heparin sodium salt (Sodium heparinate) 是一种抗凝血剂，可以干扰血凝过程中的多个环节。Heparin sodium salt 可以与抗凝血酶 III 可逆结合，加快凝血酶因子 IIa 和 Xa 的失活速度，从而发挥抗凝作用。

规格

价格

库存

数量

50 mg

¥ 298

In stock

100 mg

¥ 417

In stock

500 mg

¥ 692

In stock

产品介绍

生物活性

产品描述	Heparin sodium salt (Sodium heparinate) is an anticoagulant that interferes with several aspects of the blood clotting process. Heparin sodium salt reversibly binds to antithrombin III and accelerates the inactivation of prothrombin factors IIa and Xa, thereby exerting an anticoagulant effect.
体外活性	方法：人类胚胎干细胞 HUES-1 用 Heparin sodium salt (10-100 ng/mL) 处理 6 天，检测细胞形态和细胞数。结果：在不存在 FGF-2 的情况下，向 hESF8 培养基中添加 Heparin sodium salt 以剂量依赖的方式促进 HUES-1 细胞增殖。在 100-200 ng/mL 的 Heparin sodium salt 下效果最大，而 1000 ng/mL 则明显有害。[1]
体内活性	方法：为研究对食物摄入量的影响，将 Heparin sodium salt (1 mg/kg) 单次腹腔注射给 C57BL6/J 小鼠。结果：Heparin sodium salt 刺激食物摄入，单次注射的食欲作用持续 6 h。注射后 1、3 和 12 h，雄性和雌性小鼠增加了食物摄入。[2]
激酶实验	In vitro assay of CYP17: The in vitro CYP17 inhibitory activity of Galeterone is evaluated using rapid acetic acid releasing assay (AARA), utilizing intact P450c17-expressing E. coli as the enzyme source. It involves the use of [21-3H]-17α-hydroxypregnenolone as the substrate, and CYP17 activity is measured by the amount of tritiated acetic acid formed during the cleavage of the C-21 side chain of the substrate. IC50 value is obtained directly from plots relating percentage inhibition versus inhibitor concentration over appropriate ranges.
别名	肝素钠, Sodium heparinate, Heparin sodium

化学信息

CAS No.	9041-08-1
密度	no data available
颜色	White
物理性状	Solid

储存&溶解度

存储	keep away from direct sunlight \| Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.
溶解度信息	H2O: 126.3 mg/mL, Sonication is recommended.

体内实验配液计算器