Name: BML-284
Brand: TargetMol
SKU: T3144
Price: 237 CNY
Availability: InStock
Rating: 5 (10 reviews)

规格

价格

库存

数量

1 mg

¥ 237

现货

5 mg

¥ 533

现货

10 mg

¥ 698

现货

25 mg

¥ 1,330

现货

50 mg

¥ 2,390

现货

100 mg

¥ 3,630

现货

200 mg

¥ 5,260

现货

500 mg

¥ 8,170

现货

1 mL x 10 mM (in DMSO)

¥ 533

现货

产品介绍

生物活性

产品描述	BML-284 (Wnt agonist 1) is a potent, selective and , cell-permeable Wnt signaling activator.
靶点活性	TCF-dependent transcriptional activity:700 nM (EC50)
体外活性	Wnt agonist 1 does not inhibit the activity of GSK-3β, and may be a useful tool in the study of physiological processes that involve the Wnt pathway. [1]
体内活性	In a Xenopus model, Wnt agonist 1 (10 μM) mimics the effects of Wnt at the whole-organism level, and affects Xenopus embryonic head specification. [1]
别名	Wnt agonist 1

化学信息

分子量	350.37
分子式	C₁₉H₁₈N₄O₃
CAS No.	853220-52-7
Smiles	COc1cccc(c1)-c1cc(NCc2ccc3OCOc3c2)nc(N)n1
密度	1.353 g/cm3 (Predicted)
颜色	Yellow
物理性状	Solid

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: < 1 mg/mL (insoluble or slightly soluble)

Ethanol: < 1 mg/mL (insoluble or slightly soluble)

DMSO: 255 mg/mL (727.8 mM), Sonication is recommended.

体内实验配方

10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (5.71 mM), Sonication is recommended.

请按顺序添加溶剂，在添加下一种溶剂之前，尽可能使溶液澄清。如有必要，可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考，体内配方并不是绝对的，请根据不同情况进行调整。

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	2.8541 mL	14.2706 mL	28.5413 mL	142.7063 mL
5 mM	0.5708 mL	2.8541 mL	5.7083 mL	28.5413 mL
10 mM	0.2854 mL	1.4271 mL	2.8541 mL	14.2706 mL
20 mM	0.1427 mL	0.7135 mL	1.4271 mL	7.1353 mL
50 mM	0.0571 mL	0.2854 mL	0.5708 mL	2.8541 mL
100 mM	0.0285 mL	0.1427 mL	0.2854 mL	1.4271 mL

体内实验配液计算器