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Astragalus polyphenols

Synonyms: 芪多酚, Astragalus polyphenols, 2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside, 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside
货号 T2964Cas号 82373-94-2 一键复制产品信息纯度: 99.92%
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2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Astragalus polyphenols) 是分离自蓼属植物物种的根中,对5-HETE、HHT、thromboxane B2的形成具有抑制作用。

Astragalus polyphenols

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纯度: 99.92%

货号 T2964Cas号 82373-94-2

别名 芪多酚, Astragalus polyphenols, 2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside, 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside

2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Astragalus polyphenols) 是分离自蓼属植物物种的根中,对5-HETE、HHT、thromboxane B2的形成具有抑制作用。

Astragalus polyphenols
其他形式的 “Astragalus polyphenols”:
规格价格库存数量
1 mg
¥ 123
现货
5 mg
¥ 257
现货
10 mg
¥ 410
现货
25 mg
¥ 811
现货
50 mg
¥ 1,150
现货
100 mg
¥ 1,570
现货
200 mg
¥ 2,330
现货
1 mL x 10 mM (in DMSO)
¥ 283
现货
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纯度: 99.92%
颜色: 黄色
性状: Solid
资源下载: COA HPLC HNMR产品操作手册

产品介绍


Astragalus polyphenols AI Summary
Astragalus polyphenols exhibits multiple bioactivities, including the inhibition of Mg2+ ATPase and Ca2+ ATPase activities in human red blood cells, with a dose-dependent effect and a notable IC50 value of 240,000 nM for Ca2+ ATPase. It also possesses antifungal properties, showing minimum inhibitory concentrations (MICs) against Valsa mali at 6.25 µg/mL, Pyricularia oryzae at 22.3 µg/mL, and several other fungi with MIC values greater than 50.0 µg/mL. Furthermore, Astragalus polyphenols inhibits tyrosinase activity in mouse Melan-a cells, reducing L-DOPA Vmax at concentrations of 60 µM, 120 µM, and 240 µM, with Ki values ranging from 2,500,000 nM to 3,100,000 nM. It also demonstrates a 103% inhibition of tyrosinase activity in the presence of forskolin after 3 days at 60 µM. Conversely, it activates mushroom tyrosinase at concentrations between 0.12 to 75 µg/L with a relative activity of 12.0%. However, it shows a high IC50 value of over 50,000 nM for PTP1B inhibition and 40,000,000 nM for antioxidant activity via DPPH radical scavenging..
Note: Summary generated by AI. Data source: ChEMBL
生物活性
产品描述
2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside (Astragalus polyphenols) is a compound isolated from the roots of Polygonum species, inhibits the formation of 5-HETE, HHT and thromboxane B2.
别名
芪多酚, Astragalus polyphenols, 2,3,5,4'-Tetrahydroxystilbene-2-O-b-D-glucopyranoside, 2,3,5,4'-Tetrahydroxystilbene 2-O-β-D-glucoside, 2,3,4',5-Tetrahydroxystilbene 2-O-D-glucoside
化学信息
分子量406.38
分子式C20H22O9
CAS No.82373-94-2
SmilesOC[C@H]1O[C@@H](Oc2c(O)cc(O)cc2\C=C\c2ccc(O)cc2)[C@H](O)[C@@H](O)[C@@H]1O
密度1.593 g/cm3 (Predicted)
储存&溶解度
存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息
DMSO: 123.75 mg/mL (304.52 mM), Sonication is recommended.
体内实验配方
10% DMSO+40% PEG300+5% Tween 80+45% Saline: 2 mg/mL (4.92 mM), Sonication is recommended.
请按顺序添加溶剂,在添加下一种溶剂之前,尽可能使溶液澄清。如有必要,可通过加热、超声、涡旋处理进行溶解。工作液建议现配现用。以上配方仅供参考,体内配方并不是绝对的,请根据不同情况进行调整。
溶液配制表
DMSO
1mg5mg10mg50mg
1 mM2.4608 mL12.3038 mL24.6075 mL123.0376 mL
5 mM0.4922 mL2.4608 mL4.9215 mL24.6075 mL
10 mM0.2461 mL1.2304 mL2.4608 mL12.3038 mL
20 mM0.1230 mL0.6152 mL1.2304 mL6.1519 mL
50 mM0.0492 mL0.2461 mL0.4922 mL2.4608 mL
100 mM0.0246 mL0.1230 mL0.2461 mL1.2304 mL
该溶液配制表仅适用于固体产品。对于液体产品,请根据标明的浓度或密度计算稀释方案。

计算器

  • 摩尔浓度 计算器
  • 稀释 计算器
  • 配液 计算器
  • 分子量 计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法:
比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL, 一共给药动物10只,您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH2O, 那么您的工作液浓度为2 mg/mL
母液配置方法:2 mg 药物溶于 100 μL DMSO ( 母液浓度为 20 mg/mL ), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:100 μL DMSO 母液, 添加 400 μL PEG300 混匀澄清, 再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH2O 混匀澄清
以上为“体内实验配液计算器”的使用方法举例,并不是具体某个化合物的推荐配制方式,请根据您的实验动物和给药方式选择适当的溶解方案。
方案所需的各类助溶剂如: DMSOPEG300PEG400Tween 80SBE-β-CD玉米油等, 均可在TargetMol网站点击购买。
1 请输入动物实验的基本信息
mg/kg
g
μL
2 请输入动物体内配方组成,不同的产品配方组成不同,如有配方需求,可先联系我们提供正确的体内配方。
% DMSO
%
% Tween 80
% Saline/PBS/ddH2O

剂量转换

对于不同动物的给药剂量换算,您也可以参考 更多

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