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Adiponectin receptor

Adiponectin receptor 1 (AdipoR1) is a protein which in humans is encoded by the ADIPOR1 gene. It is a member of the progestin and adipoQ receptor (PAQR) family, and is also known as PAQR1.The adiponectin receptors, AdipoR1 and AdipoR2, serve as receptors for globular and full-length adiponectin and mediate increased AMPK and PPAR-α ligand activities, as well as fatty acid oxidation and glucose uptake by adiponectin.

Cat. No.	Product Name	CAS No.	Purity
T2257	AdipoRon 化合物AdipoRon	924416-43-3	99.86%
T2257	AdipoRon 是可口服的脂联素受体激动剂，能够与AdipoR1(Kd:1.8 μM)及AdipoR2(Kd:3.1 μM)结合。
T2766	Arctiin 牛蒡子苷	20362-31-6	99.81%
T2766	Arctiin 是一种从牛蒡种子中提取的植物木酚素，具有抗癌作用。
T6519	Gramine 芦竹碱	87-52-5	98.14%
T6519	Gramine是从芦竹中得到的一种生物碱，是脂联素受体激动剂，对 AdipoR2 和 AdipoR1 的IC50值分别为 3.2 和 4.2 µM。它也是小鼠和人β2-肾上腺素受体激动剂，具有抗肿瘤、抗炎和抗病毒作用。
T4190	Ticlopidine 噻氯匹定	55142-85-3	98%
T4190	Ticlopidine 是抗血栓前药。它是CYP2C19人肝细胞色素的抑制剂，抑制 CYP2C9 及 CYP3A4。他是变构CD39的非竞争性抑制剂，能够阻断 NTPDase 同工酶，对NTPDase2和NTPDase3的IC50分别为 170 µM 和 149 µM。