RIP2 kinase inhibitor 1 is a potent and selective receptor interacting inhibitor of protein 2 (RIP2) kinase(RIP2 FP with an IC50 of 0.03 μM ),and is used for autoinflammatory disorders.
RIP2 Kinase Inhibitor 4 is a highly potent and selective RIPK2 PROTAC compound that efficiently degrades RIPK2 (with a pIC50 value of 8) and effectively inhibits the release of TNF-α.
Pulchellin is a type-2 Ribosome Inactivating Protein (RIP), whose action mechanism proposed would be initiate by B-chain binding on glycoconjugate onto the cell surface (lectinic chain). pulchellin isoforms toxicity is the interaction between B-chain lect