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  • Drug-Linker Conjugates for ADC
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抑制剂&激动剂
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TargetMol产品目录中 "mmaf"的结果
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TargetMol产品目录中 "

mmaf

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  • 抑制剂&激动剂
    46
    TargetMol | Inhibitors_Agonists
  • 重组蛋白
    7
    TargetMol | Recombinant_Protein
  • 抗体抑制剂
    4
    TargetMol | Inhibitory_Antibodies
  • PROTAC
    8
    TargetMol | PROTAC
  • 天然产物
    1
    TargetMol | Natural_Products
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    3
    TargetMol | Isotope_Products
  • 检测抗体
    1
    TargetMol | Antibody_Products
  • MMAF
    一甲基澳瑞他汀 F, MonoMethyl auristatin F
    T3256745017-94-1
    MMAF (MonoMethyl auristatin F) 是一种抗有丝分裂剂,通过阻断微管蛋白的聚合来抑制细胞分裂,用作抗肿瘤药物和抗体偶联药物的细胞毒性成分。
    • ¥ 108
    In stock
    规格
    数量
  • D8-MMAF
    Monomethylauristatin F D8
    T10949
    D8-MMAF is a microtubule destroyer, deuterated form of MMAF.
    • 待询
    规格
    数量
  • MMAF-OMe
    Monomethyl auristatin F methyl ester
    T12081863971-12-4
    MMAF-OMe (Monomethyl auristatin F methyl ester) 是一种抗微管蛋白剂,能够抑制 MDAMB435 5T4,MDAMB361DYT2,MDAMB468 和 Raji (5T4-) 这四种肿瘤细胞,IC50值分别为 0.056 nM,0.166 nM,0.183 nM 和 0.449 nM。它也是ADC 细胞毒素。
    • ¥ 123
    In stock
    规格
    数量
  • MMAF Hydrochloride
    Monomethylauristatin F Hydrochloride
    T161211415246-68-2
    MMAF Hydrochloride is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF Hydrochloride is an effective tubulin polymerization inhibitor and is used as an antitumor compound.
    • ¥ 661
    1-2周
    规格
    数量
  • MMAF sodium
    Monomethylauristatin F sodium
    T161221799706-65-2
    MMAF sodium is widely used as a cytotoxic component of antibody-drug conjugates (ADCs) such as Vorsetuzumab mafodotin and SGN-CD19A. MMAF sodium is an effective tubulin polymerization inhibitor and is used as an antitumor agent.
    • ¥ 36400
    10-14周
    规格
    数量
  • MAL-di-EG-Val-Cit-PAB-MMAF
    T18251
    MAL-di-EG-Val-Cit-PAB-MMAF refers to a chemical compound that comprises the linker (MAL-di-EG-Val-Cit-PAB) and the potent blocker of tubulin polymerization (MMAF, Monomethyl auristatin F)[1].
    • 待询
    规格
    数量
  • MC-Alkyl-Hydrazine Modified MMAF
    T183061404071-64-2
    MC-Alkyl-Hydrazine Modified MMAF is a potent antitumor drug-linker conjugate for ADC, incorporating Modified MMAF, a tubulin inhibitor, through a noncleavable MC-Alkyl-Hydrazine linkage[1].
    • 待询
    规格
    数量
  • MC-Val-Cit-PAB-MMAF
    T18326863971-17-9
    MC-Val-Cit-PAB-MMAF is an antibody-drug conjugate (ADC) component that exhibits antitumor properties through the action of the tubulin inhibitor, monomethyl auristatin F (MMAF), which is connected by a cathepsin-cleavable linker, MC-Val-Cit-PAB.
    • ¥ 2380
    5日内发货
    规格
    数量
  • PEG4-aminooxy-MMAF
    T185341415246-35-3
    PEG4-aminooxy-MMAF is a drug-linker conjugate designed for antibody-drug conjugates (ADC) that exhibits potent antitumor activity. It incorporates MMAF, a powerful antitubulin agent, connected through a non-cleavable PEG4 linker[1].
    • 待询
    规格
    数量
  • D8-MMAF hydrochloride
    T19269
    D8-MMAF hydrochloride is a deuterated form of MMAF hydrochloride, which is a microtubule destroyer.
    • ¥ 9385
    待询
    规格
    数量
  • OncoFAP-GlyPro-MMAF
    T205295
    OncoFAP-GlyPro-MMAF 是一种 ADC 药物-连接子偶联物 (Drug-Linker Conjugates for ADC),具有强大的抗肿瘤活性。其由 Monomethylauristatin F 和连接子组成,可用于 ADCs 的合成。
    • 待询
    规格
    数量
  • DBCO-PEG4-VC-PAB-MMAF
    T205799
    DBCO-PEG4-VC-PAB-MMAF 是一种是一种点击反应型 Drug-linker,含有 DBCO 基团,可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。MMAF 是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂,DBCO-PEG4-VC-PAB-MMAF 可用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • Gly-Gly-Gly-MMAF
    T205804
    Gly-Gly-Gly-MMAF 是一种转肽酶反应型 Drug-linker,具有创新型高度稳定可降解连接子,MMAF 是一种有效的微管蛋白聚合 (tubulin polymerization) 抑制剂,常用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • MAL-PEG4-MMAF
    T27975
    MAL-PEG4-MMAF is a maleimido functionalized derivative of MMAF (Monomethyl auristatin F) with PEG4 linker. The maleimido functional group can be easily conjugated to protein carriers (such as antibody or enzyme). MAL-PEG4-MMAF is a useful precursor for ma
    • 待询
    规格
    数量
  • Modified MMAF-C5-COOH
    Modified MMAF-C5-COOH
    T388301404071-65-3
    Modified MMAF-C5-COOH is a drug-linker conjugate for ADC.
    • ¥ 10600
    待询
    规格
    数量
  • DBM-MMAF
    T392381810001-93-4
    DBM-MMAF is a drug-linker conjugate composed of a potent antitubulin agent MMAF and a linker DBM to make antibody drug conjugate (ADC).
    • ¥ 3750
    待询
    规格
    数量
  • DBCO-PEG4-Val-Cit-PAB-MMAF
    DBCO-PEG4-Val-Cit-PAB-MMAF
    T397482244602-23-9
    DBCO-PEG4-Val-Cit-PAB-MMAF is a chemical compound that comprises a cleavable 4 unit polyethylene glycol antibody-drug conjugate (ADC) linker known as DBCO-PEG4-Val-Cit-PAB, and a highly effective inhibitor of tubulin polymerization called MMAF. This compound serves as a valuable component in the synthesis of ADCs.
    • 待询
    规格
    数量
  • DBCO-PEG4-MMAF
    DBCO-PEG4-MMAF
    T398972360411-65-8
    DBCO-PEG4-MMAF is an antibody-drug conjugate (ADC) component that exhibits potent antitumor activity. It combines the tubulin polymerization inhibitor MMAF with a cleavable linker, DBCO-PEG4, to target cancer cells effectively.
    • ¥ 18700
    待询
    规格
    数量
  • Modified MMAF
    T741771352202-47-1
    Modified MMAF 是一种用于构建 Antibody-drug Conjugate (ADC) 的 ADC 细胞毒素,适用于癌症靶向研究。
    • 待询
    规格
    数量
  • Mal-PEG8-Val-Cit-PAB-MMAF
    T77892
    Mal-PEG8-Val-Cit-PAB-MMAF 是一种用于抗体药物偶联体 (ADC) 的药物-连接物复合体 (drug-linker conjugate for ADC)。该化合物由一个可降解的 ADC linker 以及有效的微管蛋白抑制剂 MMAE 组成。
    • 待询
    规格
    数量
  • Val-Cit-PAB-MMAF sodium
    T77894
    Val-Cit-PAB-MMAFsodium为抗体药物偶联物(ADC)的活性组分,其结构由ADC连接子(肽类连接子Val-Cit-PAB)与高效微管蛋白聚合抑制剂MMAF通过偶联形成。
    • 待询
    规格
    数量
  • Val-Cit-PAB-MMAF
    T80883863971-56-6
    Val-Cit-PAB-MMAF为抗体偶联药物(ADC)活性组分,其结构由ADC linker(肽Val-Cit-PAB)与高效的微管蛋白聚合抑制剂MMAF通过偶联形成。
    • 待询
    8-10周
    规格
    数量
  • N3-PEG3-VC-PAB-MMAF
    T817152757277-32-8
    N3-PEG3-VC-PAB-MMAF(Comp T-88-5)为药物连接物偶联物,结合了ADC连接物N3-PEG3-VC-PAB与微管蛋白抑制剂MMAF,作为点击化学试剂,在具有Azide基团的特点下,能够通过铜催化叠氮-炔环加成反应(CuAAc)与含Alkyne基团的分子反应,同时也能通过菌株促进炔-叠氮环加成反应(SPAAC)与含DBCO或BCN基团的分子作用。
    • 待询
    8-10周
    规格
    数量
  • Fmoc-MMAF-OMe
    T82382863971-38-4
    Fmoc-MMAF-OMe,一种具有Fmoc保护基团的抗癌剂和微管蛋白聚合抑制剂,其活性成分MMAF作为经典抗体偶联药物(ADCs)中的细胞毒性(ADC Cytotoxin)组分。
    • 待询
    8-10周
    规格
    数量