ck 17

CK-17 is an interleukin-1 antagonist and an IL-1 blocker, which inhibits fibroblast proliferation in a concentration-dependent manner.

Calcon (Mordant Black 17) 是一种钙生化指示剂。

Sematilide is a blocker of selective IKr channel.

CK176 is a capsid targeted inhibitor of HIV-1 replication. CK176 shows an 11-fold improvement over I-XW-053 in blocking HIV-1 replication in primary human peripheral blood mononuclear cells (PBMCs).

Sematilide hydrochloride (CK-1752) 是一种选择性的 IKr 通道阻滞剂。Sematilide 以浓度依赖性抑制延迟整流钾通道 (K+current)，IC50为 25 μM。Sematilide 是一种 III 类抗心律不齐剂。

Casein kinase1δ-IN-31 (Compound 16) 是一种酪蛋白激酶 (CK) 的有效抑制剂，其对CK1α、CK1δ和p38α的IC50值分别为196 nM、17 nM和18 nM。同时，它也能抑制Double Homeobox 4 (DUX4)，IC50为1200 nM。