Ligand for Target Protein for PROTAC

Cat. No.	Product Name	CAS No.	Purity
T18601	Desmethyl-QCA276 化合物 T18601	2126819-55-2	98%
T18601	Desmethyl-QCA276, the QCA276-based moiety, binds to cereblon ligand via a linker to form PROTAC to degrade BET. QCA276 is a BET inhibitor with an IC50 of 10 nM, ...
T18650	Ch55-O-C3-NH2 化合物 T18650	144298-98-6	98%
T18650	Ch55-O-C3-NH2, also known as RAR ligand 1, is a ligand derived from the Ch55 compound that specifically targets RAR. Through a linker, Ch55-O-C3-NH2 interacts wi...
T13843	PROTAC IRAK4 ligand-1 化合物 T13843	2357108-39-3	98%
T13843	PROTAC IRAK4 ligand-1 is a synthetic ligand for interleukin-1 receptor-associated kinase 4.
T10320	Androgen receptor antagonist 1 化合物 T10320	1338812-36-4	98%
T10320	Androgen receptor antagonist 1 is an orally available full androgen receptor antagonist (IC50: 59 nM). It can be used in the synthesis of PROTAC AR degraders, wh...
T13888	SLF 化合物 T13888	195513-96-3	98%
T13888	SLF is a synthetic ligand for FK506-binding protein (FKBP)( with an affinity of 3.1 μM for FKBP51 and an IC50 of 0.22 μM for FKBP12). SLF can be used in the synt...
T10345	Apcin-A 化合物 T10345	1683617-62-0	98%
T10345	Apcin-A is an anaphase-promoting complex (APC) inhibitor. It interacts strongly with Cdc20 and inhibits the ubiquitination of Cdc20 substrates. Apcin-A can be us...
T12558	PROTAC BET-binding moiety 2 化合物 T12558	916493-82-8	98%
T12558	PROTAC BET-binding moiety 2 is an BET bromodomain inhibitor.
T12905	SI-109 化合物 T12905	T12905	98%
T12905	SI-109 is a potent inhibitor of STAT3 SH2 domain (Ki=9 nM),and with antitumor activity.
T17940	Estrone-N-O-C1-amido 化合物 T17940	138219-84-8	98%
T17940	Estrone-N-O-C1-amido (ERα ligand 1) is an estrogen ligand derived from Estrone that specifically binds to estrogen receptor α (ERα). Through a linker, Estrone-N-...
T10734L	CDK ligand for PROTAC hydrochloride 化合物 T10734L	T10734L	98%
T10734L	CDK ligand for PROTAC hydrochloride is a CDK inhibitor with antitumor activity. It has been used to design PROTAC CDK4/6 degraders.
T13841	PROTAC Her3-binding moiety 1 化合物 T13841	1603845-36-8	98%
T13841	PROTAC Her3-binding moiety 1 is a Her3 Ligand for PROTAC.
T13086	I-BET762 carboxylic acid 化合物 T13086	1300019-38-8	98%
T13086	I-BET762 carboxylic acid is an inhibitor of BRD4(pIC50 of 5.1).
T12557	PROTAC BET-binding moiety 1 化合物 T12557	2093387-77-8	98%
T12557	PROTAC BET-binding moiety 1 is a key intermediate in the synthesis of high affinity BET inhibitors
T18053	Ipatasertib-NH2 化合物 T18053	1001382-14-4	98%
T18053	Ipatasertib-NH2 (GDC-0068-NH2;RG7440-NH2) is a ligand for target protein AKT for PROTAC, binds to lenalidomide, a ligand of ubiquitin E3 ligase cereblon (CRBN), ...
T13914	SLF-amido-C2-COOH 化合物 T13914	1092369-24-8	98%
T13914	SLF-amido-C2-COOH is a synthetic ligand for FKBP (SLF), and can be used in the synthesis of PROTACs.
T18611	AP1867-2-(carboxymethoxy) 化合物 T18611	2230613-03-1	98%
T18611	AP1867-2-(carboxymethoxy), a moiety based on the synthetic FKBP12F36V-directed ligand AP1867, connects to the CRBN ligand through a linker to generate dTAG molec...
T13915	PROTAC BRD9-binding moiety 1 化合物 T13915	2097512-23-5	98%
T13915	PROTAC BRD9-binding moiety 1 that binds to BRD9, and used for inhibiting BRD9 activity, based on PROTAC.
T18592	Imatinib carbaldehyde 化合物 T18592	1436868-85-7	98%
T18592	Imatinib carbaldehyde (also known as CGP-57148B carbaldehyde) is a compound derived from Imatinib, an inhibitor of the ABL protein. Imatinib carbaldehyde binds t...
T10743	CDK9-IN-11 化合物 T10743	2748368-15-0	98%
T10743	CDK9-IN-11 是一种有效的CDK9抑制剂，可作为 PROTAC CDK9 Degrader-1 的配体。
T10522	BET-IN-6 化合物 T10522	2570470-39-0	98%
T10522	BET-IN-6 是一种有效且高亲和力的BRD2/BRD4抑制剂。BET-IN-6 是靶蛋白 BRD2/4 的配体，可用于合成 PROTAC BRD2/BRD4 degrader-1 。