ri-2

RI-2 是一种可逆的RAD51抑制剂，IC50值为 44.17 μM，可抑制人体细胞中的同源重组修复。

PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).

SRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction phenotypes in neurons.

SRI-29329 是一种有效的、特异性的 CDC 样激酶抑制剂，对 CLK1、CLK2 和 CLK4 的 IC50 分别为 78 nM、16 nM 和 86 nM。

SRI-29574 是一种作用于多巴胺转运体 (DAT) 的别构调节剂,能部分抑制 DAT 的摄取 (IC50=2.3 nM),同时也对羟色胺转运体 (SERT) 与去甲肾上腺素转运体 (NET) 的摄取有一定的抑制作用.该化合物可用于探究 DAT 的功能及其调控机制,是研究中的重要工具.

24R-Calcipotriol (PRI 2202) is an impurity of Calcipotriol, a ligand of VDR-like receptors.

KARI 201 是一种竞争性和选择性的酸性鞘磷脂酶 (ASM) 抑制剂，IC50为 338.3 nM，并具有良好的脑渗透性。同时，KARI 201 也是生长素释放肽受体 (ghrelin receptor) 的激动剂。该化合物能够改善与阿尔茨海默病相关的神经病理特征。

KARI 201 hydrochloride 是一种选择性、能够渗透脑部的竞争性酸性鞘磷脂酶 (ASM) 抑制剂，其IC50值为338.3 nM。同时，它也是一种生长素释放肽受体(ghrelin receptor)的激动剂。KARI 201 hydrochloride 能够改善与阿尔茨海默病相关的神经病理特征。

Imidazole mustard is an inhibitor of purine nucleoside synthesis.

TSRI265 is a novel αvβ3 ligand, disrupting the integrin-MMP2 interaction and showing antiangiogenic activit, inhibiting angiogenesis and tumor growth in vivo.

Tri-o-cresyl phosphate (Standard) is the standard substance of Tri-o-cresyl phosphate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tricresyl phosphate is an organophosphate compound. It is used as a plasticizer and diverse other applications.

RI(dl)-2 TFA 是一种有效的选择性 RAD51 介导的 D 环形成 (RAD51-mediated D-loop formation) 抑制剂，IC50为 11.1 μM，并抑制人细胞中的同源重组 (HR) 活性，IC50为 3.0 μM。

STAD-2 is a cell permeable akap disruptor, selectively binding to pka-rii and blocking the interaction of pka-ri with akap

5’-O-TBDMS-dG is a modified nucleoside. 5’-O-DMT-2’-O-TBDMS-rI can be used in the synthesis of deoxyribonucleic acid or nucleic acid.

5'-O-DMT-2'-O-TBDMS-rI is a modified nucleoside utilized in the synthetic process of deoxyribonucleic acid (DNA) or nucleic acid.

5'-O-DMT-2'-O-TBDMS-rI, a modified nucleoside, finds application in deoxyribonucleic acid (DNA) or nucleic acid synthesis.

AKAP disruptor. Selectively binds PKA-RI with high affinity (KD values are 6.2 and 12.1 nM for the RIα and β subunits, respectively) and blocks its interaction with AKAP. Inhibits type I PKA-mediated phosphorylation in live cells. Cell permeable.

RI-STAD-2 是一种具有高亲和力的干扰肽，专门针对蛋白激酶 A (PKA) 的调节亚基 RI。通过模拟 AKAPs 的 α-螺旋结构域，RI-STAD-2 干扰 AKAPs 与 PKA-RI 的结合，影响 PKA 的活性和细胞内定位。它与 PKA-RI 的二聚化/锚定 (D/D) 结构域相互作用，可用于研究 AKAPs 和 PKA-RI 在心血管疾病及癌症等病理过程中的作用。