Substance P Receptor Antagonist 1 has the potential function in gastrointestinal disorders, inflammatory diseases, respiratory, and central nervous system disorders.
CS-003 free base (CS-003) is a triple tachykinin receptor antagonist with high affinity for human (neurokinin) NK1, NK2 and NK3 receptors, with Ki values of 2.3 nM and 0.54 nM, respectively And 0.74 nM. CS-003 free base (CS-003) has therapeutic effects on
CGP 45715A (irukostat) is a potent peptide-leukotriene antagonist used to treat respiratorydiseases by antagonizing the bronchial constriction, mucus secretion, and inflammatory effects of these leukotrienes.