neuropeptide y

Neuropeptide Y (29-64), amide, human is a biologically active 36-amino acid peptide.

Neuropeptide Y (22-36), a 15-amino acid fragment of Neuropeptide Y, is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems.

Neuropeptide Y (human) TFA, a compound implicated in Alzheimer's disease (AD), exhibits protective effects against β-Amyloid toxicity in rat cortical neurons.

Neuropeptide Y(29-64) is a 36 amino acid peptide, a fragment of Neuropeptide Y.

Neuropeptide Y (NPY) (3-36) is a C-terminal fragment of NPY, a neuropeptide involved in controlling appetite, blood pressure, cardiac contractility, and intestinal secretion. NPY (3-36) is an endogenous peptide produced by cleavage of NPY by dipeptidyl peptidase 4 (DPP-4). It binds selectively to the NPY receptor Y2 (Ki = 0.41 nM in CHP 234 cells) over the Y1 receptor, where it does not bind at concentrations up to 1 μM. NPY (3-36) (0.1 nM) increases migration of human umbilical vein endothelial cells (HUVECs) by 80% after 12 hours in an in vitro wound closure assay. NPY (3-36) corresponds to residues 3-36 of the human and rat protein sequence.

Neuropeptide Y (29-64), amide, human acetate 参与阿尔茨海默病 (AD) 并保护大鼠皮质神经元免受 β-淀粉样蛋白毒性。

神经肽Y（Neuropeptide Y, NPY）是一种参与调节食欲、血管收缩、心脏收缩力和肠道分泌的神经肽，同时也是NPY受体Y1、Y2和Y5的激动剂。它在全身范围内表达。NPY能够在表达大鼠Y1或Y2以及表达大鼠Y5的HEK293细胞中选择性抑制由forskolin诱导的cAMP积累，而对表达大鼠Y4受体的L-M(TK-)细胞的影响较小（EC50分别为0.15、2.7、0.66和>1,000 nM)。在分离的豚鼠心脏模型中，NPY能够增加灌注压（EC30 = 1.3 nM）。神经内注射NPY（300 pmol 动物）能够在大鼠中增加食物摄取量。

Neuropeptide Y (29-64), amide, human (TFA) is involved in Alzheimer's disease (AD) and protects rat cortical neurons against β-Amyloid toxicity.It is showed that Neuropeptide Y (29-64), amide, human (TFA) is able to protect cortical neurons from Aβ25-35 t

Galanin(1-13)-Neuropeptide Y (25-36) amide 是一种兼具高亲和力的甘丙肽受体和甘丙肽之配体。

Neuropeptide Y (3-36) (porcine) 是一种针对 Y2 亚型的 NPY 受体的激动剂，同时也通过一种尚未明确的受体来调控大鼠的摄食行为。

[Pro34]Neuropeptide Y, porcine是一种选择性NPY受体(Y1受体)激动剂，引起豚鼠腔静脉血管收缩。

Neuropeptide Y (3-36) (human, rat) is a metabolite of neuropeptide Y (NPY) generated by dipeptidyl peptidase-4 (DPP4). Known as a selective Y2 receptor agonist, Neuropeptide Y (3-36) (human, rat) effectively reduces the release of norepinephrine via the Y2 receptor[1][2].

Potent neuropeptide Y (NPY) Y5 receptor agonist (pEC50 values are 7.82, 6.28, 6.44 and > 6 at rat Y5, Y4, Y1 and Y2 receptors respectively) that displays > 26-fold, > 1000-fold and > 1000-fold selectivity over Y1, Y2 and Y4 receptors respectively. Induces

Neuropeptide Y (18-36) (porcine) 是一种与Neuropeptide Y(NPY)心脏受体进行竞争性拮抗的化合物。该化合物通过浓度依赖的方式，抑制I-NPY与心室膜的结合，具有IC50值158 nM和Ki值140 nM。Neuropeptide Y (18-36) (porcine) 主要用于充血性心力衰竭的研究。

Neuropeptide Y (2-36) (porcine) 是一种具有 97.14% 与大鼠 人类同源性的猪源性神经肽。作为一种大鼠神经肽受体激动剂，其对Y5、Y2和Y1受体的EC50值为1.2, 1.6 和 3.4 nM，能显著增加食物摄入量，适用于肥胖和饮食失调研究。

Neuropeptide Y (NPY) is a 36-amino acid neuropeptide that exerts its activity via G-protein-coupled receptors. NPY is widely distributed in the peripheral and central nervous systems. It modulates a variety of physiological processes, e.g. the central reg

N-Acetyl [Leu28, Leu31] neuropeptide Y (24–36) 为neuropeptide Y Y2 receptor的特异性激动剂。此化合物能够减少麻醉大鼠心脏的迷走神经活性。

[Leu31,Pro34]-Neuropeptide Y(human,rat) TFA 是一种针对神经肽 YY1受体的特定激动剂，并亦能够激活Y4和Y5受体。该化合物能提高麻醉大鼠的血压并增加食物摄入。

Neuropeptide Y, porcine 是存在于猪脑中的多肽，能够抑制分泌素刺激的胰腺分泌。

[D-Trp34]-Neuropeptide Y TFA，一种高效且选择性的神经肽Y (NPY) Y5受体激动剂，其在NPY Y1、Y2、Y4及Y6受体上的活性显著低于Y5受体。该化合物能显著提高大鼠的食物摄入量。

High affinity neuropeptide Y Y1 receptor agonist (Ki = 0.39 nM). Also shows affinity for Y4 and Y5 receptors.

Neuropeptide Y, porcine TFA 是存在于猪脑中的多肽，能够抑制分泌素刺激的胰腺分泌。

Neuropeptide Y 13-36 (porcine) 是选择性的神经肽 Y2 受体激动剂。

Neuropeptide Y (13-36), amide, human is a neuropeptide Y receptor agonist.