igfbp-3

IGFBP-3peptide 是由18个氨基酸组成的胰岛素样生长因子结合蛋白-3，能够结合Humanin和Hyaluronan，并阻断CD44与Hyaluronan的相互作用。

NBI-31772 hydrate is a powerful inhibitor of the interaction between insulin-like growth factor (IGF) and IGF-binding proteins (IGFBPs). It acts as a nonpeptide ligand, effectively releasing bioactive IGF-I from the IGF-I IGFBP-3 complex (Ki values for all six human subtypes range from 1-24 nM). This compound demonstrates significant anxiolytic and antidepressant-like effects [1] [2] [3].