dgat1

DGAT1-IN-1是 DGAT1的高效抑制剂，在 Hep3B 细胞过表达 DGAT1裂解物中，测得IC50低于10nM。

DGAT-1 inhibitor 2是有效的DGAT-1抑制剂，具有减肥功效。

PF-04620110 是一种口服有效的甘油二酯酰基转移酶 -1(DGAT1)选择性抑制剂，IC50为 19 nM。

GSK2973980A is a selective Acyl-CoA:diacylglycerol acyltransferase 1 (DGAT1) inhibitor (IC50: 3 nM).

AZD3988 是一种具有口服活性和高效性的二酰甘油酰基转移酶-1（DGAT-1）的抑制剂，可用于研究糖尿病和肥胖。

T863 (DGAT-3) 是口服有效的二酰基甘油酰基转移酶1 选择性抑制剂。T863结合DGAT1的酰基辅酶A 结合位点，抑制三酰甘油在细胞内的合成。

Pradigastat (LCQ-908) 是一种具有口服活性、有效性和选择性的二酰基甘油酰基转移酶 1 (DGAT1) 抑制剂，可用于治疗便秘，可用于研究肥胖和糖尿病。

7beta-Methoxyrosmanol inhibited acyl CoA:diacylglycerol acyltransferase (DGAT)1 activity, with the IC50 values ranging from 39.5 ± 0.6 to 144.2 ± 3.1 μM.

JNJ-DGAT1-A is a DGAT1-selective inhibitor.

DGAT1-IN-3 是一种选择性的、有效的，口服具有活力的 DGAT-1 抑制剂，能够抑制人类 DGAT-1 (IC50: 38 nM) 和大鼠 DGAT-1 (IC50: 120 nM)。DGAT1-IN-3 能够用于肥胖、血脂异常和代谢综合征的研究。

Xanthohumol 是从啤酒花中分离到的黄酮类化合物，可抑制 COX-1 和 COX-2 活性，具有抗肿瘤，抗血管生成的作用，还具有抗多种病毒的活性。

A 922500 (DGAT-1 Inhibitor 4a) 是一种口服有效的二酰甘油酰基转移酶 1(DGAT-1)选择性抑制剂，抑制小鼠和人 DGAT-1 的IC50s 分别为9 nM，22 nM。

ABT-046 是一种具有口服活性、选择性和高效性的二酰基甘油酰基转移酶 1 (DGAT-1) 抑制剂，可用于研究代谢疾病。

Diacylglycerol Acyltransferase Inhibitor-1, a diacylglycerol acyltransferase (DGAT1) inhibitor, effectively suppresses the activity of DGAT1.

AZD7687 is a potent and selective DGAT1 inhibitor with an IC50 value of 80 nM (hDGAT1). IC50 value: 80 nM [1] Target: DGAT1 in vitro: Plasma AZD7687 exposure was measured repeatedly. AZD7687 markedly reduced postprandial TAG excursion with a steep concent

AZD2353 is a potent inhibitor of diacylglycerol acetyl transferase 1 (DGAT1).

Amidinomalonamide hydrochloride is a chemical reagent used in the preparation of pyrimidooxazines used as DGAT1 inhibitors. This drug has potential use as an anti-obesity treatment.

ALN29882 is a glycerolipid, that is located at the plasma membrane. It is made up of two fatty acid chains that are covalently attached to a single glycerol molecule with the help of an ester linkage. 18:1 DG has been used as a diacyl-glycerol source in diacylglycerol O-acyltransferase 1 (DGAT1) assay. It has also been used as substrate to assess compounds as potential inhibitors of DGAT-1 in DGAT-1 enzyme assay. It is suitable to use in lipid-protein overlay screen assay with the recombinant protein His-AtROP6.

Guaiacylglycerol-8-O-4'-(sinapyl alcohol) ether 作为一种DGAT1抑制剂,其IC50值为92.7 μM,可从Eleutherococcus senticosus中提取得到.该化合物主要用于研究与II型糖尿病及肥胖相关的生物医学领域.