购物车
  • 全部删除
  • TargetMol
    您的购物车当前为空

纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs)

纤维生长因子受体 (Fibroblast Growth Factor Receptors, FGFRs) 是与纤维生长因子 (Fibroblast Growth Factor ,FGF) 蛋白家族成员结合的受体。FGFR 由一个由三个免疫球蛋白样结构域组成的细胞外配体结构域、一个跨膜螺旋结构域和一个具有酪氨酸激酶活性的细胞内结构域组成。FGF/FGFR信号通路与多种癌症有关。目前有作用于所有 FGFR1-4 和其他蛋白质的非选择性 FGFR 抑制剂,以及作用于部分/全部 FGFR1-4 的一些选择性 FGFR 抑制剂,例如AZD4547、BGJ398、JNJ42756493和PD173074。

FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00395
FGFR1 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 42 kDa and the accession number is P11362-7.
  • ¥ 5180
现货
规格
数量
FGFR1 Protein, Human, Recombinant (His)
TMPY-01011
FGFR1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 31 kDa and the accession number is H9FRD4.
  • ¥ 3820
现货
规格
数量
TargetMol | Inhibitor Sale
FGFR4 Protein, Human, Recombinant (hFc)
TMPY-00806
FGFR4 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 66 kDa and the accession number is P22455-1.
  • ¥ 3820
5日内发货
规格
数量
FGFR4 Protein, Mouse, Recombinant (His & hFc)
TMPY-01019
FGFR4 Protein, Mouse, Recombinant (His & hFc) is expressed in HEK293 mammalian cells with His and hFc tag. The predicted molecular weight is 67 kDa and the accession number is A0A0R4IZY3.
  • ¥ 3820
5日内发货
规格
数量
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His)
TMPY-06036
FGFR1 Protein, Human, Recombinant (alpha (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 40.5 kDa and the accession number is P11362-7.
  • ¥ 2260
现货
规格
数量
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
TMPJ-00391
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3.
  • ¥ 550
5日内发货
规格
数量
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00686
FGFR3 alpha (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 37.09 kDa and the accession number is E9QNJ9.
  • ¥ 2660
5日内发货
规格
数量
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His)
TMPK-00847
FGFR2 beta (IIIb) Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 26.3 kDa and the accession number is P21803-2.
  • ¥ 3100
5日内发货
规格
数量
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00384
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
  • ¥ 2210
5日内发货
规格
数量
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00391
Four distinct genes encoding closely related FGF receptors, FGF R1-4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid‑box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain.FGFR3 is tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of cell proliferation, differentiation and apoptosis.
  • ¥ 5180
5日内发货
规格
数量
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00392
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession number is P11362-7.
  • ¥ 2210
5日内发货
规格
数量
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
TMPK-00398
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3.
  • ¥ 3400
5日内发货
规格
数量
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00401
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs.
  • ¥ 5180
5日内发货
规格
数量
FGFR4 Protein, Human, Recombinant (His & Avi)
TMPK-00379
FGFR4 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
  • ¥ 1470
5日内发货
规格
数量
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00380
FGFR4 beta Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 26.90 kDa and the accession number is P22455-1.
  • ¥ 5180
5日内发货
规格
数量
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00381
FGFR4 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22455-1.
  • ¥ 5180
5日内发货
规格
数量
FGFR2 Protein, Mouse, Recombinant (His)
TMPY-03389
FGFR2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 28.5 kDa and the accession number is AAA39377.1.
  • ¥ 3820
5日内发货
规格
数量
FGFR1 Protein, Human, Recombinant (beta (IIIb), His)
TMPY-06034
FGFR1 Protein, Human, Recombinant (beta (IIIb), His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 30.8 kDa and the accession number is H9FRD4.
  • ¥ 5770
现货
规格
数量
FGFR2IIIc Protein, Human, Recombinant (hFc)
TMPJ-00388
FGFR2IIIc Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802.
  • ¥ 550
5日内发货
规格
数量
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi)
TMPK-00385
FGFR3 beta (IIIc) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.1 kDa and the accession number is P22607-1.
  • ¥ 2660
5日内发货
规格
数量
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00386
FGFR3 alpha (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.1 kDa and the accession number is P22607.
  • ¥ 5180
5日内发货
规格
数量
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00388
FGFR3 alpha (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 41.4 kDa and the accession number is P22607-2.
  • ¥ 2210
5日内发货
规格
数量
FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated
TMPK-00394
Fibroblast growth factor receptor 1 (FGFR1) transmits signals through the plasma membrane regulating essential cellular processes like division, motility, metabolism, and death. Overexpression of FGFR1 is observed in numerous tumors and thus constitutes an attractive molecular target for selective cancer treatment. FGFR1 beta (IIIc) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 25.23 kDa and the accession number is P11362-7.
  • ¥ 5180
5日内发货
规格
数量
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi)
TMPK-00389
FGFR3 beta (IIIb) Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 30.5 kDa and the accession number is P22607-2.
  • ¥ 2660
5日内发货
规格
数量