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(S)-3-Hydroxybutanoic acid

Name: (S)-3-Hydroxybutanoic acid
Brand: TargetMol
SKU: T13979
Price: 110 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: L-β-Hydroxybutyric acid, L-(+)-3-Hydroxybutyric acid, (S)-β-Hydroxybutanoic acid, (S)-3-羟基丁酸

货号 T13979Cas号 6168-83-8 一键复制产品信息纯度: 99.74%

很棒

(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) 是一种正常的人体代谢产物，在患有抑郁症的老年患者中升高。它在人类的肝脏中由乙酰-CoA 合成，当血糖低时能够被脑用作能量来源。

(S)-3-Hydroxybutanoic acid

一键复制产品信息

很棒

纯度: 99.74%

货号 T13979Cas号 6168-83-8

别名 L-β-Hydroxybutyric acid, L-(+)-3-Hydroxybutyric acid, (S)-β-Hydroxybutanoic acid, (S)-3-羟基丁酸

规格	价格	库存
50 mg	¥ 110	现货
100 mg	¥ 198	现货
500 mg	¥ 642	现货
1 g	¥ 937	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.74%

颜色: 白色

性状: Solid

资源下载: COA LCMS HNMR产品操作手册

产品介绍

(S)-3-Hydroxybutanoic acid AI Summary

(S)-3-Hydroxybutanoic acid exhibits significant bioactivity by inhibiting various transporters and enzymes. It displays inhibition of mouse Oat6-mediated [3H]ES uptake and mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes, with inhibition constants (Ki) of 190,546.07 nM and 3,235,936.57 nM for Oat6 and Oat1, respectively. It shows inhibitory activity against mouse Oat1 with a Ki value around 3,220,000 nM, assessed both through fluorometric analysis and uptake assays in Xenopus oocytes. Moreover, it acts as an inhibitor of BAZ2B with a potency of 1,000 nM and HP1-beta Chromodomain Interactions with Methylated Histone Tails at 79,432.8 nM. Additionally, (S)-3-Hydroxybutanoic acid induces DNA re-replication in SW480 colon adenocarcinoma cells with a potency of 145.8 nM. The affinity and transport kinetics of the compound in Xenopus laevis oocytes are indicated by a Km value of 824,000,000 nM. These combined activities suggest that (S)-3-Hydroxybutanoic acid could be relevant in studies related to transporter inhibition and cancer cell proliferation..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	(S)-3-Hydroxybutanoic acid (L-(+)-3-Hydroxybutyric acid) is a normal human metabolite that has been found elevated in geriatric patients remitting from depression. (S)-3-Hydroxybutanoic acid is synthesized in the liver from acetyl-CoA in humans, and can be used as an energy source by the brain when blood glucose is low.
别名	L-β-Hydroxybutyric acid, L-(+)-3-Hydroxybutyric acid, (S)-β-Hydroxybutanoic acid, (S)-3-羟基丁酸

化学信息

分子量	104.1
分子式	C₄H₈O₃
CAS No.	6168-83-8
Smiles	C[C@H](O)CC(O)=O
密度	1.195 g/cm3

储存&溶解度

存储

Pure form: -20°C for 3 years | In solvent: -80°C for 1 year Shipping with blue ice/Shipping at ambient temperature.

实际储存温度请以COA为准

溶解度信息

H2O: 257.5 mg/mL (2473.58 mM), Sonication is recommended.

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	9.6061 mL	48.0307 mL	96.0615 mL	480.3074 mL
5 mM	1.9212 mL	9.6061 mL	19.2123 mL	96.0615 mL
10 mM	0.9606 mL	4.8031 mL	9.6061 mL	48.0307 mL
20 mM	0.4803 mL	2.4015 mL	4.8031 mL	24.0154 mL
50 mM	0.1921 mL	0.9606 mL	1.9212 mL	9.6061 mL
100 mM	0.0961 mL	0.4803 mL	0.9606 mL	4.8031 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

β-Hydroxybutanoic acid L-b-Hydroxybutyric acid L-beta-Hydroxybutyric acid L-3-Hydroxybutyric acid Inhibitor inhibit Human Endogenous Metabolite EndogenousMetabolite Endogenous Metabolite b-Hydroxybutanoic acid beta-Hydroxybutanoic acid 3-Hydroxybutanoic acid (S)3Hydroxybutanoic acid (S) 3 Hydroxybutanoic acid

(S)-3-Hydroxybutanoic acid

(S)-3-Hydroxybutanoic acid