ri2

RI-2 是一种可逆的RAD51抑制剂，IC50值为 44.17 μM，可抑制人体细胞中的同源重组修复。

TSRI265 is a novel αvβ3 ligand, disrupting the integrin-MMP2 interaction and showing antiangiogenic activit, inhibiting angiogenesis and tumor growth in vivo.

24R-Calcipotriol (PRI 2202) is an impurity of Calcipotriol, a ligand of VDR-like receptors.

PNRI-299 is a selective inhibitor of AP-1 transcription(IC50 of 20 uM ).

KARI 201 是一种竞争性和选择性的酸性鞘磷脂酶 (ASM) 抑制剂，IC50为 338.3 nM，并具有良好的脑渗透性。同时，KARI 201 也是生长素释放肽受体 (ghrelin receptor) 的激动剂。该化合物能够改善与阿尔茨海默病相关的神经病理特征。

KARI 201 hydrochloride 是一种选择性、能够渗透脑部的竞争性酸性鞘磷脂酶 (ASM) 抑制剂，其IC50值为338.3 nM。同时，它也是一种生长素释放肽受体(ghrelin receptor)的激动剂。KARI 201 hydrochloride 能够改善与阿尔茨海默病相关的神经病理特征。

SRI-29132 is potent; highly permeant of the blood-brain barrier; and selective for LRRK2 kinase activity, therefore effective in attenuating pro-inflammatory responses in macrophages and in rescuing neurite retraction phenotypes in neurons.

Imidazole mustard is an inhibitor of purine nucleoside synthesis.

SRI-29329 是一种有效的、特异性的 CDC 样激酶抑制剂，对 CLK1、CLK2 和 CLK4 的 IC50 分别为 78 nM、16 nM 和 86 nM。

SRI-29574 是一种作用于多巴胺转运体 (DAT) 的别构调节剂,能部分抑制 DAT 的摄取 (IC50=2.3 nM),同时也对羟色胺转运体 (SERT) 与去甲肾上腺素转运体 (NET) 的摄取有一定的抑制作用.该化合物可用于探究 DAT 的功能及其调控机制,是研究中的重要工具.

Tri-o-cresyl phosphate (Standard) is the standard substance of Tri-o-cresyl phosphate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Tricresyl phosphate is an organophosphate compound. It is used as a plasticizer and diverse other applications.