pyrrolizidine

Usaramine (Mucronatine) 是从 Crolatalaria pallida 种子中分离得到的一种吡咯里嗪类生物碱。它对 Lactuca sativa var 具有植物毒性。

Retrorsine 特异性地抑制肝细胞增殖，并在肝损伤后唤起小肝细胞样祖细胞。逆转录酶可用于肝细胞损伤的研究。

Seneciphylline 是一种有毒的吡咯烷核生物碱，存在于千里光植物中。它显著增加了环氧水合酶和谷胱甘肽-S-转移酶的特性，但导致细胞色素 P-450 和相关单加氧酶特性的抑制。

1,2-Epoxy-1-hydroxymethylpyrrolizidine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T125765。

Monocrotaline 是一种提取自猪屎豆种子的11元大环吡咯里西啶生物碱，具有抑制有机阳离子转运蛋白OCT-1和OCT-2的作用，其IC50值分别为36.8 µM和1.8 mM。Monocrotaline具有抗肿瘤活性，对肝癌细胞（如HepG2）表现出一定的细胞毒性，同时常用于啮齿动物中诱导肺动脉高压模型。

Lamellarin D (Lamellarine D) 是一种从海洋无脊椎动物中分离的六环吡咯生物碱,是一种线粒体靶向型的拓扑异构酶 I 抑制剂，也是一种促凋亡剂。

Lasiocarpine is a pyrrolizidine alkaloid, it has acute cytotoxicity in human and hepatic cell lines.

Senkirkin is a pyrrolizidine alkaloid with hepatotoxicity.

Ligularine is a hepatotoxic otonecine-type pyrrolizidine alkaloid isolated from Ligularia hodgsonii, a Chinese traditional antitussive medicine.

Isatidine is a pyrrolizidine alkaoid.

Supinine is a pyrrolizidine alkaloid.

(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).

Jacobine N-oxide is a pyrrolizidine alkaloid compound found in thrips-resistant Senecio hybrids.

Erucifoline, a pyrrolizidine alkaloid, is present in the aerial components of Senecio aquaticus.

Echimidine N-oxide, a pyrrolizidine alkaloid, exhibits significant inhibitory activity against acetylcholinesterase (AChE) with an IC50 value of 0.347 mM.

Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.

7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid.

Senecionine acetate (O-Acetylsenecionine)为吡咯烷核生物碱，通过使游离巯基失活，抑制线粒体及其区域内Ca2+的螯合。

Rinderine N-oxide，一种来源于R. graeca的吡咯里西啶生物碱。

Adonifoline（阿多尼弗林碱）是一种具有口服肝毒性的吡咯里西啶（pyrrolizidine）生物碱，通过代谢活化生成具有反应活性的吡咯代谢物（如 DHP）引发肝毒性。

7-Acetylintermedine (Standard) 是 7-Acetylintermedine 的标准品。适用于定量分析、质量控制及生化实验等相关研究。7-Acetylintermedine is a hepatotoxic botanical pyrrolizidine alkaloid.

Jacobine N-oxide (Standard) 是 Jacobine N-oxide 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Jacobine N-oxide is a pyrrolizidine alkaloid compound found in thrips-resistant Senecio hybrids.

(+)-Intermedine (Standard) 是 (+)-Intermedine 的标准品。适用于定量分析、质量控制及生化实验等相关研究。(+)-Intermedine, a pyrrolizidine alkaloid (PA), shows remarkable cytotoxic activity against neural progenitor cells (NPCs).

Indicine N-oxide (Standard) 是 Indicine N-oxide 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Indicine N-oxide (NSC 132319), a pyrrolizidine alkaloid, serves as an antitumor agent in pediatric cancer and solid tumors research.