promyelocytic

Ginsenoside F5 是从人参中提取的一种天然产物，通过凋亡途径显着抑制 HL-60 细胞的生长。

Nordalbergin 是一种香豆素，分离自Dalbergia sissoo的木皮中。 它能够显著性的诱导 HL-60 细胞的分化。

Aphidicolin is a potent inhibitor of cellular deoxyribonucleic acid synthesis and inhibits the growth of herpes simplex virus[2]. Aphidicolin is an inhibitor of DNA polymerase α and δ, prevents mitotic cell division by interfering with the activity of DNA

Aspergillin PZ is a fungal metabolite originally isolated from A. awamori. It induces morphological deformation of P. oryzae conidia when used at a concentration of 89 nM. Aspergillin PZ is active against S. epidermidis (MIC = 20 μM) but not S. aureus, E. coli, or B. cereus (MICs = >20 μM). It is cytotoxic to HL-60 promyelocytic leukemia cells (IC50 = 56.61 μM) but not THP-1 acute monocytic leukemia or PC3 prostate cancer cells (IC50s = >80 μM).

Toosendanin 是一种从杜鹃花果实皮中提取的三萜，具有杀虫和抗炎活性，可用于研究缓解疼痛。

(-)-Syringaresinol (DL-Syringaresinol) 来源于番荔枝 Annona Montana 的茎。 (-)-Syringaresinol 通过 G1 期阻滞和诱导细胞凋亡来抑制人早幼粒细胞 HL-60 细胞的增殖，并具有抗癌活性。

Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) 是一种天然的潜在神经炎症抑制剂，分离自鼠尾草 (Alhagi sparsifoliaShap) 。

Episyringaresinol 4'-O-β-D-glncopyranoside (Standard) 是 Episyringaresinol 4'-O-β-D-glncopyranoside 的标准品。适用于定量分析、质量控制及生化实验等相关研究。Episyringaresinol 4'-O-β-D-glncopyranoside ((-)-Syringaresinol 4-O-β-D-glucopyranosi) 是一种天然的潜在神经炎症抑制剂，分离自鼠尾草 (Alhagi sparsifoliaShap) 。

Nidulal 诱导人类早幼粒细胞白血病细胞分化。此外，在 COS-7 细胞中，Nidulal 选择性地激活 AP-1 依赖的信号转导过程。

Yadanziolide C induces differentiation with cultured HL-60 promyelocytic leukemia cells.

Dehydrocrebanine has strong activity against promyelocytic leukemia cells (HL-60) with an IC50 of 2.14 ug/mL. It also shows potent antimalarial activity with an IC50 value of 70 ng/ml.

Desmethylrocaglamide is a novel inducer of cellular differentiation using HL-60 promyelocytic cells, it may be a drug for the prevention and therapy of cancer. It also has insecticidal activity.

(+)-Norglaucine shows cytotoxic activity toward the tumor cell lines B16-F10 (mouse melanoma), HepG2 (human hepatocellular carcinoma), K562 (human chronic myelocytic leukemia) and HL-60 (human promyelocytic leukemia) and non-tumor peripheral blood mononuc

Hericenone J (Compound 6) 是一种具有抗癌活性的芳香化合物，来源于猴头菇 (Hericium erinaceum)。Hericenone J 具有细胞毒性，能够显著降低 HL-60 人急性早幼粒细胞白血病细胞的活性，IC50值为 4.13 μM。Hericenone J 可作为白血病研究的潜在对象。