paq

PAQ is a neuroprotective agent. It protects dopaminergic neurons from cell death without inhibiting glial cell proliferation in a rat midbrain culture model of Parkinson's disease when used at a concentration of 10 μM. PAQ (25 or 50 mg/kg, twice per day) prevents loss of dopaminergic neurons in the substantia nigra in a mouse model of Parkinson's disease induced by MPTP.

Lapaquistat acetate (TAK-475) 是一种角鲨烯合酶抑制剂，具有潜在的抗炎活性。Lapaquistat acetate 减弱他汀类药物诱导的人骨骼肌细胞中的细胞毒性，保护豚鼠免受塞利伐他汀诱导的肌毒性，可用于研究高胆固醇血症和甲羟戊酸激酶缺乏症。

Paquinimod (ABR 25757) 是一种特异性的 S100A8 S100A9 抑制剂，具有口服活性。Paquinimod 具有免疫调节活性，可以用于治疗系统性红斑狼疮。

Lapaquistat is a cholesterol biosynthesis inhibitor and is the active metabolite of TAK-475. Lapaquistat can reduce statin-induced myotoxicity in lipid-lowering therapy.

Propaquizafop, a phenoxyisopropionic acid derivative, is used as a herbicide.

Leiocarpaquinone is a bioactive chemical from root of Uentilago leiocarpa Benth. (Rhamnaceae).

L-Topaquinone is a metabolite of dopaquione, an important intermediate in melanogenesis.

Diatrizoate meglumine (Renocal) 是泛影酸盐的葡甲胺盐，它是一种有机的、碘化的、不透射线的 X 射线造影剂，用于放射诊断。