Nalidixicacid (Standard) 是 Nalidixicacid 的标准品,适用于定量分析、质量控制及生化实验等相关研究。Nalidixicacid (NSC-82174) 是一种喹诺酮类抗生素,对革兰氏阳性和革兰氏阴性细菌有效。它在较低浓度下有抑菌作用,而在较高浓度下有杀菌作用。它抑制 DNA 促旋酶和拓扑异构酶 IV 的亚基,并可逆地阻止易感细菌中的 DNA 复制。
Isoreserpiline, an indole alkaloid discovered in R. tetraphylla, exhibits a range of biological activities. This compound enhances the antibacterial efficacy of nalidixicacid against both nalidixicacid-sensitive and -resistant E. coli strains through a synergistic effect. Additionally, at a dosage of 25 mg kg, it mitigates amphetamine-induced hyperactivity in mice.