dnase i

Gentamicin sulfate (SCH9724) 是一种广谱的氨基糖苷类抗生素，具有口服活性。Gentamicin sulfate 可以用于抑制敏感生物体中的蛋白质合成。

Deoxyribonuclease I (DNase I) 是提纯蛋白质常用的一种酶，具有潜在的抗炎和抗癌活性，可用于研究细菌感染和真菌感染。

A-20832 inhibits resolvase-promoted site-specific recombination postsynaptically at strand cleavage. It does not inhibit resolvase binding to res, as measured by filter binding, or synapse formation. DNase I analysis in the presence of A-20832 indicates t

Nargenicin is a macrolide antibiotic that selectively inhibits the growth of S. aureus, methicilin resistant S. aureus (MRSA), and M. luteus (MICs = 0.6, 0.3, and 2.5 μg ml, respectively) over a panel of 11 Gram-positive and Gram-negative bacteria (MICs = >80 μg ml). [1] It dose-dependently inhibits S. aureus DnaE in the presence of DNase I-activated DNA and E. coli DnaE when used at concentrations of 0.00001-0.1 and 0.01-100 μg mL, respectively. [2] In murine BV-2 microglial cells, nargenicin (1 μM) inhibits cytokine expression and nitric oxide production induced by LPS.[3] Nargenicin (200 μM), when used in combination with 1,25-dihydroxyvitamin D3 or all-trans retinoic acid , reduces cell proliferation by 37-47% and increases cell differentiation by 82-85% in HL-60 human myeloid leukemia cells.[4]

Mn007 是一种牛胰腺 DNase I 抑制剂，通过形成分子聚集有效抑制其活性，其 IC50 值达到 45 µM。此外，Mn007 还能抑制人类全血中化脓性杆菌 (S. pyogenes) 的生长。