squalene synthase

RPR107393 free base 是一种具有选择性和高效性的角鲨烯合酶 (SQS) 抑制剂，可用于研究神经系统疾病和内分泌与代谢疾病。

Lapaquistat acetate (TAK-475) 是一种角鲨烯合酶抑制剂，具有潜在的抗炎活性。Lapaquistat acetate 减弱他汀类药物诱导的人骨骼肌细胞中的细胞毒性，保护豚鼠免受塞利伐他汀诱导的肌毒性，可用于研究高胆固醇血症和甲羟戊酸激酶缺乏症。

Squalene synthase-IN-1（compound 1）是一种通过抑制Squalene Synthase来发挥降血脂作用的有效药物。该化合物也展现了卓越的抗氧化和抗炎特性，能显著降低葡萄糖水平和氧化应激，且不引起毒性。

FIN56 是一种铁死亡特异性诱导剂，能结合并激活角鲨烯合酶，可通过诱导 GPX4 降解来诱导铁死亡。

WC-9 is a squalene synthase inhibitor. It acts by binding to TcSQS and HsSQS.

Zaragozic acid C is an effective inhibitor of squalene synthase.

Squalestatin 2 is an inhibitor of squalene synthase.

Squalestatin 3 is an inhibitor of squalene synthase.

DF-461 is an inhibitor of squalene synthase.

YM-53601 是一种高效性角鲨烯合酶 (SQS) 抑制剂，可抑制啮齿动物的脂肪生成生物合成和脂质分泌。YM-53601 是一种降胆固醇剂，抑制法呢基二磷酸法呢基转移酶 1 (FDFT1) 。YM-53601 具有潜在的抗病毒活性，在体内增强阿霉素介导的 HCC 生长停滞和细胞死亡。

Zaragozic acid D inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.

Zaragozic acid D(2) inhibits squalene synthase and ras farnesyl-protein transferase isolated from the keratinophilic fungus Amauroascus niger.

E5700 is a novel squalene synthase inhibitor with oral activity.

J-104118 potentially inhibits squalene synthase.

YM-75440 is an squalene synthase inhibitor with oral activity.

BMS-188494 is a squalene synthase inhibitor used as an anti-cholesterol drug.

BMS-187745 is a squalene synthase inhibitor.

Zaragozic acid A trisodium 是真菌的代谢产物，具有作为角鲨烯合成酶可逆竞争性抑制剂的功能。