rank 1

LTF4 is a cysteinyl-leukotriene produced in vitro, but not reported to date in vivo. It is formed by the incubation of LTE4 with γ-glutamyl transpeptidase and glutathione. LTF4 is a weak agonist in its ability to contract vascular smooth muscle. [1] The rank order of potency of the cysteinyl-leukotrienes to contract vascular smooth muscle is LTD4 > LTC4 > LTE4 >> LTF4. [1] [2]

Garvicin KS（GakB）是由34个氨基酸组成的肽，与GakA和GakC共同构成细菌素GarKS。该肽不仅能抑制成纤维细胞活力和增殖，还表现出与GakA组合时的优异稳定性、抗菌效能以及对成纤维细胞作用。针对MSSA的抑制，Garvicin KS肽的MIC值显示GakB的活性最强，其次为GakC，GakA活性最低。