gp-36

CGP 36216 hydrochloride is a potent and selective antagonist of GABAB receptors (IC50: 43 µM).

CGP 36742 is a selective antagonist of the GABAB receptor that can penetrate the blood-brain barrier after peripheral administration (IC50: 32 μM). It is useful in the treatment of depression.

CGP36216 hydrochloride是选择性GABA突触前受体拮抗剂，其Ki值与GABAB受体结合为0.3μM。适用于焦虑及创伤相关障碍研究。

Isamoltane is a serotonin 5-HT1 Receptor Antagonist