dexamethasone

Dexamethasone 是一种糖皮质激素受体激动剂和 IL 受体调节剂，具有抗炎、免疫抑制和凋亡诱导活性，能抑制巨噬细胞中炎性 miRNA-155 外泌体的产生，显著降低中性粒细胞及单核细胞的炎症因子表达，抑制 LPS 诱导的巨噬细胞炎症反应并诱导自噬，常用于诱导抑郁症、肌肉萎缩症和高血压动物模型，且在 COVID-19 研究中具有潜力。

Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体，有抗炎和免疫抑制活性。它可研究眼部感染。

Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比， DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。

Dexamethasone acetate monohydrate is an adrenocortical steroid. It is used in the treatment of many conditions, including rheumatic problems, a number of skin diseases, asthma, severe allergies, chronic obstructive lung disease, brain swelling, croup, and antibiotics

Avanafil (TA1790) 是一种高活性PDE-5抑制剂，IC50=5.2 nM，对PDE1，PDE6和PDE11活性较低。

Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

Dexamethasone Beloxil is a glucocorticoid, Anti-inflammatory Agent.

Dexamethasone cipecilate is a long-acting intranasal corticosteroid and a highly lipophilic anti-inflammatory corticosteroid.

6β-hydroxy Dexamethasone is a metabolite of dexamethasone that is more hydrophilic than the parent compound. Dexamethasone is metabolized by CYP3A4; therefore, quantification of the dexamethasone metabolites, 6α- and 6β-hydroxy dexamethasone, can be used to determine CYP3A4 enzyme activity in humans., The formation of 6-hydroxy dexamethasone metabolites is species-specific, with hamsters producing the highest amount. In rats, dexamethasone hydroxylation is sex-specific, with male rats producing metabolites in similar ratios to humans and female rats producing fewer hydroxylated metabolites than male rats.

Mc-Dexamethasone is a drug-linker conjugate for ADC . Mc-Dexamethasone is made toxin Dexamethasone conjugated to the non-cleavable MC linker. Dexamethasone is a glucocorticoid receptor agonist.

Dexamethasone oxetanone (Dex-Ox) is a glucocorticoid-selective derivative of Dexamethasone (Dex) compound. It acts as an antiglucocorticoid and an antiprogestin, demonstrating notable agonist activity with both PR A and B isoforms [1] [2].

Dexamethasone sodium succinate is the acetate salt form of dexamethasone, which is a synthetic glucocorticoid; it combines high anti-inflammatory effects with low mineralocorticoid activity. At high doses (e.g. 40 mg), it reduces the immune response. Dexamethasone acetate (NEOFORDEX®) is indicated in adults for the treatment of symptomatic multiple myeloma in combination with other medicinal products. Dexamethasone has been shown to induce multiple myeloma cell death (apoptosis) via a down-regulation of nuclear factor-κB activity and an activation of caspase-9 through second mitochondria-derived activator of caspase (Smac; an apoptosis promoting factor) release. Prolonged exposure was required to achieve maximum levels of apoptotic markers along with increased caspase-3 activation and DNA fragmentation. Dexamethasone also down-regulated anti apoptotic genes and increased IκB-alpha protein levels. Dexamethasone apoptotic activity is enhanced by the combination with thalidomide......

Dexamethasone metasulfobenzoate sodium 作为一种SARS-CoV-2核酸外切酶(ExoN)抑制剂，能够与ExoN的催化位点发生结合。

Dexamethasone-d5 是 Dexamethasone 的氘代化合物。

Dexamethasone 9,11-epoxide 是一种萃取得到的化合物，是制备地塞米松的中间体。

Dexamethasone Sodium Phosphate (Dexadreson) 是一种白细胞介素受体调节剂，具有抗炎和免疫抑制作用。它属于类固醇合成药物的强效糖皮质激素类。

Dexamethasone-d4 是 Dexamethasone 的氘代化合物。Dexamethasone 的 CAS 号为 50-02-2。Dexamethasone是一种糖皮质激素受体激动剂和一种 IL 受体调节剂。在脂多糖诱导的巨噬细胞炎症反应中，它抑制含有炎性 microRNA-155 的外泌体的产生。

Dexamethasone (Standard) 是 Dexamethasone 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Dexamethasone 是一种糖皮质激素受体激动剂和 IL 受体调节剂，具有抗炎、免疫抑制和凋亡诱导活性，能抑制巨噬细胞中炎性 miRNA-155 外泌体的产生，显著降低中性粒细胞及单核细胞的炎症因子表达，抑制 LPS 诱导的巨噬细胞炎症反应并诱导自噬，常用于诱导抑郁症、肌肉萎缩症和高血压动物模型，且在 COVID-19 研究中具有潜力。

Dexamethasone acetate (Standard) 是 Dexamethasone acetate 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Dexamethasone acetate (NSC 39471) 是一种糖皮质素类甾体，有抗炎和免疫抑制活性。它可研究眼部感染。

Dexamethasone palmitate (Standard) 是 Dexamethasone palmitate 的标准品，适用于定量分析、质量控制及生化实验等相关研究。Dexamethasone palmitate (DXP) (DXP) 是 Dexamethasone 的前药。Dexamethasone 是糖皮质激素受体激动剂。与Dexamethasone 相比， DXP 对糖皮质激素受体的亲和力低 47 倍。DXP 显示出抗炎活性。

Dexamethasone phosphate (Standard) is the standard substance of Dexamethasone phosphate, and it is applicable for quantitative analysis, quality control, and related research in biochemical experiments. Dexamethasone phosphate is a synthetic adrenal corticosteroid. It also has potent anti-inflammatory properties.

Dexamethasone β-D-glucuronide (sodium) 是用于糖生物学研究的生化试剂。糖生物学探讨糖的结构、合成、生物学和进化，包括碳水化合物化学、聚糖的形成与降解、蛋白质-聚糖的识别，以及聚糖在生物系统中的功能。该领域与基础研究、生物医学和生物技术紧密相连。

Dexamethasone Phosphate disodium (EGP437. Dex-Phos) 是糖皮质激素受体激动剂。

LD03-DEX为地塞米松前体化合物，展现出免疫抑制的活性。