首页 工具
登录
购物车

搜索结果

Search Results for " dynorphin "
Targets Recommended: Opioid Receptor

32

抑制剂 & 化合物

3

重组蛋白

如果没找到您满意的产品或者您对产品有其他要求,可以联系我们专业顾问为您提供针对性的合理建议。     QQ咨询       网站留言咨询

提交您的定制咨询

点击图片重新获取验证码
Cat. No. Product Name Target Signaling Pathways
TP1179L Porcine dynorphin A(1-13) acetate

Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Porcine dynorphin A(1-13) acetate (Dynorphin A Porcine Fragment 1-13 acetate)(72957-38-1 free base) 是一种有效的内源性 κ opioid 受体激动剂,在生理浓度下具有镇痛作用。暴露于强啡肽 A (1-13) 会导致单个神经元中 [Ca2+]i 的急剧增加,类似于急性 NMDA 治疗所见的增加。
T76341L [DPro10] Dynorphin A (1-11)acetate,porcine

[DPro10] Dynorphin A (1-11)acetate,porcine(94596-26-6 Free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
[DPro10] Dynorphin A (1-11)acetate,porcine 是一种高效的 κ-阿片受体激动剂,其 Ki 值为 0.13 nM。[DPro10] Dynorphin A (1-11), porcine 是一种 N-烷基化衍生物,具有镇痛活性。
TP2040L Dynorphin A acetate(80448-90-4 free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Dynorphin A acetate(80448-90-4 free base) 是一种内源性 kappa 受体激动剂。
TP1813L Dynorphin A 1-10 acetate(79994-24-4 free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Dynorphin A 1-10 acetate(79994-24-4 free base) 是一种内源性 opioid 样物质神经肽,与 κ-opioid 样物质受体的细胞外环 2 结合。 Dynorphin A (1-10) 还阻断 NMDA 激活的电流,IC50 为 42.0 μM。
TP1826L Dynorphin B (1-13) acetate(83335-41-5 free base)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Dynorphin B (1-13) acetate(83335-41-5 free base) 作为 opioid κ 受体的激动剂。
T20403 Dynorphin A (1-8)

PH-8P,Dynorphin (1-8)

Dynorphin (1-8) is an opioid octapeptide from the porcine hypothalamus. It comprises the N-terminal eight residues of dynorphin.
TP1813 Dynorphin A (1-10)

Dynorphin A 1-10

Dynorphin A (1-10), an endogenous opioid neuropeptide, binds to extracellular loop 2 of the κ-opioid receptor. Dynorphin A (1-10) also blocks NMDA-activated current with an IC50 of 42.0 μM.
TP2040 Dynorphin A

Endogenous kappa receptor agonist.
TP1179 Porcine dynorphin A(1-13)

Dynorphin A Porcine Fragment 1-13

Porcine dynorphin A (1-13) is a potent, endogenous κ opioid receptor agonist and is antinociceptive at physiological concentrations. Exposure to dynorphin A (1-13) causes acute increases in [Ca2+]i in individual neurons similar to increases seen with acut
TP1423 Dynorphin A (1-10) TFA(79994-24-4,free)

Dynorphin A (1-10) TFA

Dynorphin A (1-10) (TFA), an endogenous opioid neuropeptide, binds in the transmembrane domain of the κ-receptor.
TP1372 Dynorphin B (1-13) (TFA)(83335-41-5,free)

Dynorphin B (1-13) (TFA)

Dynorphin B (1-13), a 13 amino acid, is an extraordinarily potent opioid peptide.
TP1826 Dynorphin B (1-13)

Dynorphin B (1-13) acts as an agonist on opioid κ-receptor.
TP2243 Dynorphin (2-17), amide, porcine

Others Others
Dynorphins are a class of opioid peptides that arise from the precursor protein prodynorphin. When prodynorphin is cleaved during processing by proprotein convertase 2 (PC2), multiple active peptides are released: dynorphin A, dynorphin B, and α/β-neo-end
T75916 Dynorphin A TFA

Dynorphin A TFA, 作为一种内源性阿片肽,主要在中枢神经系统(CNS)中发挥抑制性神经传导的作用。该化合物不仅是kappa阿片受体(KOR)的高效激动剂,还能激活其他阿片受体,包括mu(MOR)和delta(DOR)。Dynorphin A TFA具有诱导神经元死亡的能力,因此在神经系统疾病的研究中具有应用价值。
T80463 Dynorphin B (1-9)

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Dynorphin B (1-9)为Dynorphin B的N-端裂解产物,属于神经肽类。其形成受到半胱氨酸肽酶非选择性抑制剂N-ethylmaleimide的阻断。
T82518 Dynorphin B 29 (pig)

Leumorphin (pig)

Dynorphin B 29 (Leumorphin) (pig) 是一种可与大脑及孤立组织系统中的多种受体交互作用的肽,并可被用于研究免疫反应。
T75988 Dynorphin A (1-10) (TFA)

Dynorphin A (1-10) (TFA) 是一种内源性的阿片样神经肽,与 κ 阿片受体 (κ-opioid receptor) 结合。Dynorphin A (1-10) (TFA) 也阻断 NMDA 激活的电流,IC50为 42.0 μM。
T76335 Dynorphin (2-17), amide (porcine)

Dynorphin (2-17), amide (porcine) 为 dynorphin 衍生物,展现镇痛效果。该化合物源自前体蛋白强啡肽原,涉及阿片肽类,参与疼痛调控、成瘾及情绪调节等生理过程。
T82520 Dynorphin (2-17) (porcine)

Dynorphin (2-17) (porcine),一种源自Prodynorphin的肽类化合物,具有缓解Morphine依赖性戒断症状的功能。
T31173 Daaccal

2-Cys-5-cys-7-mearg-8-leu-dynorphin A (1-9)-NH2

Others Others
Daaccal 可用于生命科学领域的相关研究。其产品编号为 T31173,CAS号为 103614-06-8。
T82519 Dynorphin A (1-13) amide

Dynorphin A (1-13) amide 为一种内源性阿片肽,能够拮抗吗啡引发的镇痛效应。
T83505 [DAla2] Dynorphin A (1-9) (porcine)

"[DAla2] Dynorphin A (1-9) (porcine)" 是一种强效的肽类化合物,常用于疼痛、成瘾和抑郁研究。
T75918 Dynorphin B (1-13) (TFA)

Dynorphin B (1-13) TFA 是一种阿片样 κ 受体 (κ-opioid receptor) 激动剂。
T76341 [DPro10] Dynorphin A (1-11), porcine

[DPro10] Dynorphin A (1-11), porcine 是一种 N-烷基化衍生物,是一种有效的 κ-阿片受体激动剂,其Ki 值为 0.13 nM。[DPro10] Dynorphin A (1-11), porcine 具有镇痛作用。
T76338 [DAla2] Dynorphin A (1-13), amide (porcine)

[DAla2] Dynorphin A (1-13), amide (porcine) 是一种肽,其可能作为κ阿片受体激动剂,适用于神经系统研究。
T80085 [DPro10] Dynorphin A (1-11), porcine hydrochloride

[DPro10] Dynorphin A (1-11), porcine hydrochloride,为N-烷基化衍生物,作为κ-阿片受体激动剂,具有显著活性,Ki值达0.13 nM,且表现出镇痛效果。
T76337 [DAla2, DArg6] Dynorphin A, (1-13) (porcine)

[DAla2, DArg6] Dynorphin A, (1-13) (porcine) (DADAD) 是猪脑垂体提取物中发现的阿片肽(dynorphinl-13, DYN)的一个衍生物。该化合物对GPI和MVD的外周阿片受体有高效力,但在体内易被快速分解。与原始肽相比,[DAla2, DArg6] Dynorphin A, (1-13) (porcine) 更具酶解稳定性,能有效抵抗酶的裂解作用。
T76631 (N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)

(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8) (E-2078) 是一种稳定的 Dynorphin A (1-8) 类似物,是 kappa 阿片受体 (KOR) 激动剂。
TP1071 Nociceptin

Orphanin FQ,孤菲肽

Opioid Receptor Endocrinology/Hormones; GPCR/G Protein; Neuroscience
Nociceptin (Orphanin FQ) 是一种 17 个氨基酸的多肽,是 nociceptin 受体的内源性配体,具有缓解疼痛的作用。
T23963 Daeatal

Others Others
Dynorphin A ethylamide (1-9), the opioid activities were examined in the bioassays.
T31190 Dafphedyn

Others Others
Dafphedyn, [D-Ala2, (F5) Phe4]-dynorphin 1-13-NH2 (DAFPHEDYN) is an effective analog of strong endorphin 1-13 and produces diuretic and deep analgesia when administered intravenously in rats.
T83709 LIH383 TFA

Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2

LIH383是一种趋化因子(C-X-C motif) 受体7 (CXCR7)的多肽激动剂,属于趋化因子和阿片肽清除受体。它专一性激活CXCR7 (EC50 = 0.61 nM),在3 µM浓度时,相比μ-、δ-、κ-阿片受体以及诺氨酸阿片肽(NOP)受体的β-arrestin招募实验中表现出高选择性。LIH383(3 µM)通过阻止U87-ACKR3细胞中,由非选择性阿片受体激动剂dynorphin A诱导的CXCR7对阿片肽的摄取,发挥作用。

化合物

Porcine dynorphin A(1-13) acetate
Cat.No: TP1179L
Synonym: Dynorphin A Porcine Fragment 1-13 acetate,Porcine dynorphin A(1-13) acetate(72957-38-1 free base)
Target: Opioid Receptor
[DPro10] Dynorphin A (1-11)acetate,porcine
Cat.No: T76341L
Synonym: [DPro10] Dynorphin A (1-11)acetate,porcine(94596-26-6 Free base)
Target: Opioid Receptor
Dynorphin A acetate(80448-90-4 free base)
Cat.No: TP2040L
Synonym:
Target: Opioid Receptor
Dynorphin A 1-10 acetate(79994-24-4 free base)
Cat.No: TP1813L
Synonym:
Target: Opioid Receptor
Dynorphin B (1-13) acetate(83335-41-5 free base)
Cat.No: TP1826L
Synonym:
Target: Opioid Receptor
Dynorphin A (1-8)
Cat.No: T20403
Synonym: PH-8P,Dynorphin (1-8)
Target:
Dynorphin A (1-10)
Cat.No: TP1813
Synonym: Dynorphin A 1-10
Target:
Dynorphin A
Cat.No: TP2040
Synonym:
Target:
Porcine dynorphin A(1-13)
Cat.No: TP1179
Synonym: Dynorphin A Porcine Fragment 1-13
Target:
Dynorphin A (1-10) TFA(79994-24-4,free)
Cat.No: TP1423
Synonym: Dynorphin A (1-10) TFA
Target:
Dynorphin B (1-13) (TFA)(83335-41-5,free)
Cat.No: TP1372
Synonym: Dynorphin B (1-13) (TFA)
Target:
Dynorphin B (1-13)
Cat.No: TP1826
Synonym:
Target:
Dynorphin (2-17), amide, porcine
Cat.No: TP2243
Synonym:
Target: Others
Dynorphin A TFA
Cat.No: T75916
Synonym:
Target:
Dynorphin B (1-9)
Cat.No: T80463
Synonym:
Target: Opioid Receptor
Dynorphin B 29 (pig)
Cat.No: T82518
Synonym: Leumorphin (pig)
Target:
Dynorphin A (1-10) (TFA)
Cat.No: T75988
Synonym:
Target:
Dynorphin (2-17), amide (porcine)
Cat.No: T76335
Synonym:
Target:
Dynorphin (2-17) (porcine)
Cat.No: T82520
Synonym:
Target:
Daaccal
Cat.No: T31173
Synonym: 2-Cys-5-cys-7-mearg-8-leu-dynorphin A (1-9)-NH2
Target: Others
Dynorphin A (1-13) amide
Cat.No: T82519
Synonym:
Target:
[DAla2] Dynorphin A (1-9) (porcine)
Cat.No: T83505
Synonym:
Target:
Dynorphin B (1-13) (TFA)
Cat.No: T75918
Synonym:
Target:
[DPro10] Dynorphin A (1-11), porcine
Cat.No: T76341
Synonym:
Target:
[DAla2] Dynorphin A (1-13), amide (porcine)
Cat.No: T76338
Synonym:
Target:
[DPro10] Dynorphin A (1-11), porcine hydrochloride
Cat.No: T80085
Synonym:
Target:
[DAla2, DArg6] Dynorphin A, (1-13) (porcine)
Cat.No: T76337
Synonym:
Target:
(N-Me-Tyr1,N-Me-Arg7,D-Leu-NHEt8)-Dynorphin A (1-8)
Cat.No: T76631
Synonym:
Target:
Nociceptin
Cat.No: TP1071
Synonym: Orphanin FQ,孤菲肽
Target: Opioid Receptor
Daeatal
Cat.No: T23963
Synonym:
Target: Others
Dafphedyn
Cat.No: T31190
Synonym:
Target: Others
LIH383 TFA
Cat.No: T83709
Synonym: Phe-Gly-Gly-Phe-Met-Arg-Arg-Lys-NH2
Target:
Cat. No. Product Name Species Expression System
TMPJ-00737 PDYN Protein, Human, Recombinant (His)

PDYN,ADCA,Big Dyn,Dynorphin B,PENKB,SCA23

Human HEK293 Cells
Proenkephalin-B(PDYN), belongs to the opioid neuropeptide precursor family. The N-terminal domain contains 6 conserved cysteines thought to be involved in disulfide bonding and/or processing. Leu-enkephalins, which is a type of Proenkephalin-B, compete with and mimic the effects of opiate drugs. They play a role in a number of physiologic functions, including pain perception and responses to stress. Dynorphin peptides differentially regulate the kappa opioid receptor. Dynorphin A has a typical o...
TMPJ-00386 ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated

Metalloprotease MPROT15,ACEH,Angiotensin-Converting Enzyme H...

Human HEK293 Cells
Angiotensin-Converting Enzyme 2 (ACE-2) is an integral membrane protein and a zinc metalloprotease of the ACE family, the ACE family includes somatic and germinal ACE. ACE-2 cleaves angiotensins I and II as a carboxypeptidase, ACE-2 converts angiotensin I to angiotensin 1-9, and angiotensin II to angiotensin 1-7. ACE-2 is also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. ACE-2 can be high expressed in testis, kidney and heart, in colon, small intestine and ovary at moderate...
TMPY-01635 PCSK1 Protein, Human, Recombinant (His)

proprotein convertase subtilisin/kexin type 1,SPC3,PC1,BMIQ1...

Human HEK293 Cells
Neuroendocrine convertase 1, also known as Prohormone convertase 1, Proprotein convertase 1, PCSK1 and NEC1, is an enzyme which belongs to the peptidase S8 family and Furin subfamily. PCSK1 is an enzyme that performs the proteolytic cleavage of prohormones to their intermediate (or sometimes completely cleaved) forms. It is present only in neuroendocrine cells such as brain, pituitary and adrenal, and most often cleaves after a pair of basic residues within prohormones but can occasionally cleav...

重组蛋白

PDYN Protein, Human, Recombinant (His)
Cat.No: TMPJ-00737
Species: Human
Expression System: HEK293 Cells
ACE2/ACEH Protein, Human, Recombinant (HEK293, His & Avi), Biotinylated
Cat.No: TMPJ-00386
Species: Human
Expression System: HEK293 Cells
PCSK1 Protein, Human, Recombinant (His)
Cat.No: TMPY-01635
Species: Human
Expression System: HEK293 Cells
联系我们
400-820-0310

上海市静安区江场三路238号8楼