hpt1

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Rhesus macaque, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 85.60 kDa and the accession number is A0A1D5R2B4.

Liver-intestine cadherin (CDH17) has been known to function as a tumor stimulator and diagnostic marker for almost two decades.In vivo studies showed CDH17 knockout resulted in apoptotic PC tumor death through activating caspase-3 activity. Taken together, CDH17 functions as an oncogenic molecule critical to PC growth by regulating tumor apoptosis signaling pathways and CDH17 could be targeted to develop an anti-PC therapeutic approach. CDH17 Protein, Cynomolgus, Recombinant (His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weight is 89.2 kDa and the accession number is A0A2K5X8I8.

Expression system: HEK293 Cells
Length: 1-787, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 23-787, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 23-787, Partial
Activity: ELISA

Expression system: HEK293 Cells
Length: 668-777, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 567-777, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 450-777, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 245-449, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 567-777, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-786, Partial
Activity: Not Tested

Expression system: HEK293 Cells
Length: 26-786, Partial
Activity: Not Tested

Expression system: E. coli
Length: 2-125, Full Length of Mature Protein
Activity: Not Tested

Cadherin-17 is a single-pass type I membrane protein that belongs to the cadherin superfamily. Cadherin-17 consists of one extracellular region containing seven cadherin domains and one transmembrane region but it lacks the conserved cytoplasmic domain. Cadherin-17 is expressed in the gastrointestinal tract and pancreatic duct. Cadherins are calcium dependent cell adhesion proteins and preferentially interact with each other in a homophilic manner in connecting cells. Cadherin-17 may have a role in the morphological organization of liver and intestine and involved in intestinal peptide transport.