Name: Mal-(CH2)5-Val-Cit-PAB-Eribulin
Brand: TargetMol
SKU: T39579
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

1 mg

¥ 3,090

待询

5 mg

¥ 8,150

待询

10 mg

待询

50 mg

待询

生物活性

产品描述	Mal-(CH2)5-Val-Cit-PAB-Eribulin is a potent antitumor ADC drug-linker conjugate that utilizes Eribulin, an anti-microtubule agent, connected through the Mal-(CH2)5-Val-Cit-PAB linker.
体外活性	Eribulin (E7389) is a microtubule targeting agent that is used for the research of metastatic breast cancer. Eribulin inhibits the proliferation of cancer cells by binding microtubule proteins and microtubules[2].
别名	Mal-(CH2)5-Val-Cit-PAB-Eribulin

化学信息

分子量	1328.565
分子式	C₆₉H₉₇N₇O₁₉
CAS No.	2130869-21-3
Smiles	[H][C@@]12CC(=C)[C@]([H])(CC[C@@]3([H])C[C@@H](C)C(=C)[C@@]([H])(C[C@]4([H])O[C@H](C[C@H](O)CNC(=O)OCc5ccc(NC(=O)[C@H](CCCNC(N)=O)NC(=O)[C@@H](NC(=O)CCCCCN6C(=O)C=CC6=O)C(C)C)cc5)[C@H](OC)[C@@]4([H])CC(=O)C[C@@]4([H])CC[C@]5([H])O[C@@]6([H])[C@@]7([H])O[C@@]8(C[C@@]7([H])O[C@@]6([H])[C@@]([H])(O8)[C@@]5([H])O4)CC1)O3)O2