Name: G3-C12
Brand: TargetMol
SKU: T11346
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

100 mg

待询

5日内发货

500 mg

待询

5日内发货

生物活性

产品描述	G3-C12 shows anticancer activity. is a galectin-3 binding peptide, with Kd of 88 nM.
靶点活性	GAL3:(kd)88 nM
体外活性	G3-C12 bearing opolymers N-(2-hydroxypropyl)methacrylamide (HPMA) potently and selectively targets colorectal cancer (CRC) tumour cells over-expressing galectin-3 and displays superior targetability to galectin-3 compared to the galactose bearing copolymer.G3-C12 is a galectin-3 binding peptide, with high affinity (Kd) of 88 nM, but shows no affinity for other galectin family members or to other lectins.

化学信息

分子量	1758.99
分子式	C₇₄H₁₁₅N₂₃O₂₃S₂
CAS No.	848301-94-0
Smiles	CC(C)[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H](CS)NC(=O)[C@H](CC(O)=O)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CCCN1C(=O)CNC(=O)[C@H](CS)NC(=O)[C@@H]1CCCN1C(=O)[C@@H](NC(=O)[C@H](CC(N)=O)NC(=O)[C@H](C)N)[C@@H](C)O)[C@@H](C)O)C(=O)N[C@@H](CCCCN)C(=O)N[C@@H](CCCNC(N)=N)C(O)=O
密度	1.58 g/cm3 (Predicted)
Sequence	Ala-Asn-Thr-Pro-Cys-Gly-Pro-Tyr-Thr-His-Asp-Cys-Pro-Val-Lys-Arg
Sequence Short	ANTPCGPYTHDCPVKR