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Cytidine 5'-monophosphate

Name: Cytidine 5'-monophosphate
Brand: TargetMol
SKU: TMO2752
Price: 150 CNY
Availability: InStock
Rating: 5 (10 reviews)

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很棒

纯度: 99.10%

货号 TMO2752Cas号 63-37-6

别名 胞苷酸, Cytidylic Acid, 5'-Cytidylic acid, 5'-CMP

Cytidine 5'-monophosphate (5'-Cytidylic acid) 是一种核苷酸，是组成 RNA 的基本单位之一。它由核碱基胞嘧啶，戊糖核糖和磷酸基团组成。

Cytidine 5'-monophosphate

一键复制产品信息

很棒

纯度: 99.10%

货号 TMO2752 别名 胞苷酸, Cytidylic Acid, 5'-Cytidylic acid, 5'-CMPCas号 63-37-6

Cytidine 5'-monophosphate (5'-Cytidylic acid) 是一种核苷酸，是组成 RNA 的基本单位之一。它由核碱基胞嘧啶，戊糖核糖和磷酸基团组成。

规格	价格	库存
500 mg	¥ 328	现货
5 g	¥ 415	现货
1 mL x 10 mM (in H2O)	¥ 150	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

大包装 & 定制

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.10%

颜色: 白色

性状: Solid

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资源下载:

COA LCMS HNMR 产品操作手册

产品介绍

Cytidine 5'-monophosphate AI Summary

Cytidine 5'-monophosphate exhibits a wide range of inhibitory and growth inhibition bioactivities across various assays and cell types. It inhibits alpha-2,3-sialyltransferase and alpha-2,6-sialyltransferase from rat liver with Ki values of 65,000 nM and 64,000 nM, respectively. The compound also displays significant growth inhibition against cultured L1210 mouse leukemia cells (IC50 of 0.35 μM), B16 mouse melanoma cells (IC50 of 1.5 μM), and human leukemia cell line (CCRF-CEM) with an IC50 of 100 nM. For sensitive and multidrug-resistant L1210 leukemia cells, the IC50 values are 430 nM and 410 nM, respectively, indicating similar potency. Additionally, it shows moderate inhibition of UDP-[3H]-GlcNAc import into the Golgi membranes with an IC50 greater than 100,000 nM in one test and 10,000 nM in another. It also exhibits binding energy activity with a calculated binding energy of 5.9 kcal/mol. The compound influences the phosphorylation of human YMPK in Huh7 cells, with a Km value of 56,000 nM, Kcat/Km ratio of 0.54 μM^-1s^-1, and a Kcat value of 30 s^-1. Furthermore, it inhibits bovine seminal ribonuclease and pancreatic ribonuclease A with Ki values of 1,557,900 nM and 844,200 nM, respectively, and shows a binding affinity to Escherichia coli BL21 (DE3) IspF with a Kd of 903,630 nM. Lastly, it exhibits inhibition activity against Plasmodium falciparum ODCase, human ODCase, and Methanobacterium thermoautotrophicum ODCase with Ki values greater than 10,000,000 nM, 1,400,000 nM, and 1,200,000 nM, respectively. These diverse bioactivities suggest its potential for various therapeutic applications..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	Cytidine 5'-monophosphate (5'-Cytidylic acid) is a nucleotide, one of the basic units that make up RNA. It consists of nucleobase cytosine, pentose ribose and phosphate groups.
别名	胞苷酸, Cytidylic Acid, 5'-Cytidylic acid, 5'-CMP

化学信息

分子量	323.20
分子式	C₉H₁₄N₃O₈P
CAS No.	63-37-6
Smiles	Nc1ccn([C@@H]2O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]2O)c(=O)n1
密度	2.15 g/cm3 (Predicted)

储存&溶解度

存储

Powder: -20°C for 3 years | In solvent: -80°C for 1 year | Shipping with blue ice/Shipping at ambient temperature.

溶解度信息

H2O: 7.35 mg/mL (22.74 mM), Sonication is recommended.

DMSO: Insoluble

溶液配制表

H2O

	1mg	5mg	10mg	50mg
1 mM	3.0941 mL	15.4703 mL	30.9406 mL	154.7030 mL
5 mM	0.6188 mL	3.0941 mL	6.1881 mL	30.9406 mL
10 mM	0.3094 mL	1.5470 mL	3.0941 mL	15.4703 mL
20 mM	0.1547 mL	0.7735 mL	1.5470 mL	7.7351 mL

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

Inhibitor inhibit EndogenousMetabolite Endogenous Metabolite Cytidine 5'-monophosphate Cytidine 5'monophosphate Cytidine 5' monophosphate

Cytidine 5'-monophosphate

Cytidine 5'-monophosphate