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9-(β-D-Xylofuranosyl)adenine

Name: 9-(β-D-Xylofuranosyl)adenine
Brand: TargetMol
SKU: TNU0266
Price: 123 CNY
Availability: InStock
Rating: 5 (10 reviews)

Synonyms: 木糖腺苷, Xylosyladenine, Adenine xyloside

货号 TNU0266Cas号 524-69-6 一键复制产品信息纯度: 99.97%

很棒

9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) 是一种腺嘌呤核苷类似物，是一种潜在的平滑肌血管扩张剂。9-(β-D-Xylofuranosyl)adenine 具有抗癌活性。

9-(β-D-Xylofuranosyl)adenine

一键复制产品信息

很棒

纯度: 99.97%

货号 TNU0266Cas号 524-69-6

别名 木糖腺苷, Xylosyladenine, Adenine xyloside

9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) 是一种腺嘌呤核苷类似物，是一种潜在的平滑肌血管扩张剂。9-(β-D-Xylofuranosyl)adenine 具有抗癌活性。

为众多的药物研发团队赋能，

让新药发现更简单！

规格	价格	库存
2 mg	¥ 123	现货
5 mg	¥ 197	现货
10 mg	¥ 323	现货
25 mg	¥ 535	现货
50 mg	¥ 792	现货

库存状态实时更新，以官网显示为准，现货产品可直接加购物车下单

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TargetMol的所有产品仅用作科学研究或药证申报，不能被用于人体，我们不向个人提供产品和服务。请您遵守承诺用途，不得违反法律法规规定用于任何其他用途。

实验操作小课堂

常见问题解答

选择批次:

纯度: 99.97%

颜色: 白色

性状: Solid

联系我们获取更多批次信息

资源下载:

COA HNMR HPLC 产品操作手册

产品介绍

9-(β-D-Xylofuranosyl)adenine AI Summary

9-(β-D-Xylofuranosyl)adenine exhibits a diverse range of bioactivities. It shows concentration-dependent alteration of cell morphology in various cell lines, including PRK, HeLa, Vero B, and Wi-38, and it significantly reduces growth and inhibits DNA, RNA, and protein synthesis in primary rabbit kidney cells, with an ID50 of 23.0 µg/ml. Additionally, it suppresses the proliferation of mouse myeloma SP2 cells in a concentration-dependent manner. The compound displays notable antiviral activity against numerous viruses such as Herpes simplex, vaccinia, vesicular stomatitis, polio, Coxsackie, parainfluenza, Reo, Sindbis, and forest viruses. In biochemical assays, 9-(β-D-Xylofuranosyl)adenine has demonstrated a potency of 3981.1 nM in inhibiting the proliferation of Plasmodium falciparum, 15848.9 nM and 25118.9 nM in inhibiting Tau fibril formation (using Thioflavin T binding and fluorescence polarization respectively), 22.4 nM as an inhibitor of Histone Lysine Methyltransferase G9a, and 22.4 nM as an inhibitor of human hERG channel activity. Additionally, it has a potency of 794.3 nM in preventing Marburg Virus binding or entry into cells. The compound has also been evaluated for its chemical stability, showing a drug metabolism rate constant of 0.29 x 10^-3 L/mol/min in an acid-catalyzed hydrolysis assay..

Note: Summary generated by AI. Data source: ChEMBL

生物活性

产品描述	9-(β-D-Xylofuranosyl)adenine (Adenine xyloside) is an adenine nucleoside analog that is a potential smooth muscle vasodilator.9-(β-D-Xylofuranosyl)adenine has anticancer activity.
别名	木糖腺苷, Xylosyladenine, Adenine xyloside

化学信息

分子量	267.24
分子式	C₁₀H₁₃N₅O₄
CAS No.	524-69-6
Smiles	O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](CO)[C@@H]1O

储存&溶解度

存储

溶解度信息

DMSO: 50 mg/mL (187.1 mM), Sonication is recommended.

溶液配制表

DMSO

	1mg	5mg	10mg	50mg
1 mM	3.7420 mL	18.7098 mL	37.4195 mL	187.0977 mL
5 mM	0.7484 mL	3.7420 mL	7.4839 mL	37.4195 mL
10 mM	0.3742 mL	1.8710 mL	3.7420 mL	18.7098 mL
20 mM	0.1871 mL	0.9355 mL	1.8710 mL	9.3549 mL
50 mM	0.0748 mL	0.3742 mL	0.7484 mL	3.7420 mL
100 mM	0.0374 mL	0.1871 mL	0.3742 mL	1.8710 mL

该溶液配制表仅适用于固体产品。对于液体产品，请根据标明的浓度或密度计算稀释方案。

计算器

摩尔浓度计算器
稀释计算器
配液计算器
分子量计算器

体内实验配液计算器

请在以下方框中输入您的动物实验信息后点击计算，可以得到母液配置方法和体内配方的制备方法：

比如您的给药剂量是10 mg/kg，每只动物体重20 g，给药体积100 μL，一共给药动物10只，您使用的配方为 10% DMSO + 40% PEG300 + 5% Tween 80 + 45% Saline / PBS / ddH₂O，那么您的工作液浓度为2 mg/mL。

母液配置方法：2 mg 药物溶于 100 μL DMSO （母液浓度为 20 mg/mL ）, 如您需要配置的浓度超过该产品的溶解度，请先与我们联系。

体内配方的制备方法： 取 100 μL DMSO 母液，添加 400 μL PEG300 混匀澄清，再加 50 μL Tween 80, 混匀澄清, 再加 450 μL Saline / PBS / ddH₂O 混匀澄清

以上为“体内实验配液计算器”的使用方法举例，并不是具体某个化合物的推荐配制方式，请根据您的实验动物和给药方式选择适当的溶解方案。

方案所需的各类助溶剂如： DMSO， PEG300， PEG400， Tween 80， SBE-β-CD，玉米油等，均可在TargetMol网站点击购买。

剂量转换

对于不同动物的给药剂量换算，您也可以参考更多

关键词

NucleosideAntimetabolite Nucleoside Antimetabolite/Analog Nucleoside Antimetabolite Analog 9-(β-D-Xylofuranosyl)adenine 9-(beta-D-Xylofuranosyl)adenine 9-(b-D-Xylofuranosyl)adenine

9-(β-D-Xylofuranosyl)adenine

9-(β-D-Xylofuranosyl)adenine