Powder: -20°C for 3 years | In solvent: -80°C for 1 year
7-Methoxyrosmanol (7-O-Methylrosmanol) 是一种酚类二萜,从迷迭香中分离得到,可抑制 PEPCK 和 G6Pase 启动子的 cAMP 反应。
规格 | 价格/CNY | 货期 | 数量 | |
---|---|---|---|---|
1 mg | ¥ 997 | 现货 | ||
5 mg | ¥ 2,490 | 现货 | ||
10 mg | ¥ 3,680 | 现货 | ||
25 mg | ¥ 5,880 | 现货 | ||
50 mg | ¥ 7,920 | 现货 | ||
1 mL * 10 mM (in DMSO) | ¥ 2,730 | 现货 |
产品描述 | 7-Methoxyrosmanol (7-O-Methylrosmanol) can effectively suppress FSK-induced luciferase expression under the control of the CRE, PEPCK-C and G6Pase gene promoters, it may contribute to its antihyperglycemic activity. |
体外活性 | In order to find new effective HIV protease inhibitors, two diterpenes (carnosic acid and carnosol) were isolated from rosemary (Rosmarinus officinalis L.), and rosmanol and semisynthetic derivatives (7-O-Methylrosmanol, 7-O-ethylrosmanol, and 11,12-O,O-dimethylcarnosol) were prepared. The inhibitory activity of all six compounds against HIV-1 protease was tested. The carnosic acid showed the strongest inhibitory effect (IC90 = 0.08 micrograms/ml). The same compound was also assayed against HIV-1 virus replication (IC90 = 0.32 micrograms/ml). |
别名 | 7ALPHA-甲氧基迷迭香酚, 7-O-Methylrosmanol |
分子量 | 360.44 |
分子式 | C21H28O5 |
CAS No. | 113085-62-4 |
Powder: -20°C for 3 years | In solvent: -80°C for 1 year
DMSO: 12 mg/mL (33.29 mM)
可选溶剂 | 浓度 体积 质量 | 1 mg | 5 mg | 10 mg | 25 mg |
DMSO | 1 mM | 2.7744 mL | 13.8719 mL | 27.7439 mL | 69.3597 mL |
5 mM | 0.5549 mL | 2.7744 mL | 5.5488 mL | 13.8719 mL | |
10 mM | 0.2774 mL | 1.3872 mL | 2.7744 mL | 6.936 mL | |
20 mM | 0.1387 mL | 0.6936 mL | 1.3872 mL | 3.468 mL |
对于不同动物的给药剂量换算,您也可以参考 更多...
请在以下方框中输入您的动物实验信息后点击计算,可以得到母液配置方法和体内配方的制备方法: 比如您的给药剂量是10 mg/kg,每只动物体重20 g,给药体积100 μL,一共给药动物10 只,您使用的配方为5% DMSO+30% PEG300+5% Tween 80+60% ddH2O。那么您的工作液浓度为2 mg/mL。
母液配置方法:2 mg 药物溶于 50 μL DMSO (母液浓度为 40 mg/mL), 如您需要配置的浓度超过该产品的溶解度,请先与我们联系。
体内配方的制备方法:取 50 μL DMSO 主液,加入 300 μL PEG300, 混匀澄清,再加 50 μL Tween 80,混匀澄清,再加 600 μL ddH2O, 混匀澄清。
您可能有的问题的答案可以在抑制剂处理说明中找到,包括如何准备库存溶液,如何存储产品,以及基于细胞的分析和动物实验需要特别注意的问题。
7-Methoxyrosmanol 113085-62-4 GPCR/G Protein cAMP inhibit Inhibitor 7ALPHA-甲氧基迷迭香酚 7Methoxyrosmanol 7-O-Methylrosmanol 7 Methoxyrosmanol inhibitor