thp

Pirarubicin (Theprubicin) 是一种蒽环类抗生素，是拓扑异构酶 II 抑制剂，可用于各种癌症的研究。

MS-PEG4-THP 是PEG 类PROTAC linker，可用于合成 PROTAC 分子。

THP-PEG3-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG4-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG5-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG6-OH is a polyethylene glycol (PEG)-based PROTAC linker, utilized in the synthesis of PROTACs[1]. It is also a non-cleavable three-unit PEG linker for antibody-drug conjugates (ADCs)[2].

THP-PEG8-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG8-Tos is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-SS-alcohol is a cleavable linker employed in the synthesis of antibody-drug conjugates (ADCs)[1].

THP-SS-PEG1-Boc is a cleavable ADC linker comprising a one-unit PEG, commonly employed in the synthesis of antibody-drug conjugates (ADCs)[1].

THP-SS-PEG1-Tos is a 1 unit PEG ADC linker that is cleavable. It is employed during the synthesis of antibody-drug conjugates (ADCs)[1].

THP-PEG11-OH is a PEG-based linker for PROTACs which joins two essential ligands, crucial for forming PROTAC molecules. This linker enables selective protein degradation by leveraging the ubiquitin-proteasome system within cells.

THP-PEG4-Pyrrolidine(N-Boc)-CH2OH is a polyethylene glycol (PEG) based PROteolysis TArgeting Chimera (PROTAC) linker, employed for the synthesis of PROTAC K-Ras Degrader-1, as documented in reference [1].

THP-PEG4-Pyrrolidine(N-Me)-CH2OH, a PEG-based PROTAC linker, facilitates the synthesis of PROTAC K-Ras Degrader-1[1].

Tos-PEG4-THP is a polyethylene glycol (PEG) derivative utilized as a linker in the synthesis of PROTAC K-Ras Degrader-1, a potential therapeutic compound for targeted degradation of K-Ras protein [1].

THP-1/MV-4-11 against-1 (compound 12k) 是一种 5-取代噻唑基脲类抗癌剂，对 THP-1/MV-4-11 癌细胞显示出显著的抑制作用 (IC50 分别为 29 nM 和 98 nM)。

Benzyl-PEG13-THP 是一种 PROTAC linker，隶属于 PEG 类，用于 PROTAC 分子的合成。

THP-PEG11-THP 是一种 PROTAC linker，属于 PEG 类，适用于合成 PROTAC 分子。

Azido-PEG8-THP 是一种 PEG 类的 PROTAC linker，用于合成 PROTAC 分子。这种化合物作为点击化学试剂，含有 Azide 基团，能够与含 Alkyne 基团的分子进行铜催化的叠氮-炔环加成反应（CuAAc）。它也可以与含 DBCO 或 BCN 基团的分子进行环张力驱动的炔-叠氮环加成反应（SPAAC）。

THP-PEG16-alcohol 是一款 PROTAC linker，隶属于PEG类，适用于合成PROTAC分子。

THP-PEG8-THP 是一种 PEG 类的 PROTAC linker，可用于合成PROTAC分子。

THP-PEG16-THP 是一种 PEG 类的 PROTAC linker，用于 PROTAC 分子的合成。

THP-PEG12-alcohol 是一种 PEG 类的 PROTAC linker，可用于合成PROTAC分子。

THP-PEG4-C1-OH 是一种 PEG 类 PROTAC linker，用于合成PROTAC分子。