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抑制剂&激动剂
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  • 抑制剂&激动剂
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    TargetMol | Natural_Products
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    TargetMol | Disease_Modeling_Products
  • Amiodarone hydrochloride
    盐酸胺碘酮, Nexterone, Amiodarone HCl, Amiodar HCl
    T149619774-82-4
    Amiodarone hydrochloride (Amiodarone HCl) 是一种抗心绞痛和 III 类抗心律失常药物,通过抑制钾通道和电压门控钠通道来增加心室和心房肌肉作用的持续时间,可导致心率和血管阻力降低。它通过成纤维细胞中的 ERK1 2和 p38 MAPK 信号传导诱导细胞增殖和肌成纤维细胞分化,可研究室上性和室性心律失常。
    • ¥ 274
    In stock
    规格
    数量
  • Deslanoside
    洋地黄, 去乙酰西地兰, Desacetyllanatoside C, Deacetyllanatoside C
    T818317598-65-1
    Deslanoside (Desacetyllanatoside C) 是一种快速作用的强心苷,可抑制Na-K-ATPase 膜泵,导致细胞内钠和钙浓度增加。它用于研究充血性心力衰竭和因折返机制引起的室上性心律失常,并在研究慢性心房颤动时控制心室率。
    • ¥ 616
    In stock
    规格
    数量
  • Etripamil
    MSP-2017, (-)-MSP-2017
    T152571593673-23-4In house
    Etripamil (MSP-2017) 是一种短效L 型钙通道拮抗剂,可用于治疗阵发性室上性心动过速的研究。它通过抑制房室结细胞中钙慢通道的钙离子流入,显示房室结传导并延长房室结不应期
    • ¥ 689
    In stock
    规格
    数量
  • Etripamil hydrochloride
    MSP-2017 hydrochloride, Etripamil hydrochloride, (-)-MSP-2017 hydrochloride
    T2043792560549-35-9
    Etripamil (MSP-2017) hydrochloride 是一种短效的 L-型钙通道拮抗剂,用于研究阵发性室上性心动过速 (PSVT)。它通过抑制钙离子慢通道来阻止钙离子流入,从而减缓房室结传导并延长房室结不应期。
    • 待询
    10-14周
    规格
    数量
  • Aprindine hydrochloride
    Fiboran HCl, Fibocil HCl, Aprindine HCl, Amidonal HCl
    T2137333237-74-0
    Aprindine HCl is a Class 1b antiarrhythmic agent used to manage ventricular and supraventricular arrhythmias. In one study, it delayed atrial fibrillation more than digoxin did. It has shown effectiveness when given orally.
    • ¥ 10600
    6-8周
    规格
    数量
  • Flecainide
    Tambocor,Apocard,Flecainida,Flecainidum
    T2139154143-55-4
    Flecainide acetate is a class Ic antiarrhythmic agent, it is used to treat a variety of cardiac arrhythmias including paroxysmal atrial fibrillation, paroxysmal supraventricular tachycardia, and ventricular tachycardia. It works by regulating the flow of
    • ¥ 1758
    5日内发货
    规格
    数量
  • Encainide
    Encainide,MJ9067
    T4077766778-36-7
    Encainide (MJ9067), a class IC antiarrhythmic drug, holds potential for research into life-threatening and symptomatic ventricular arrhythmias as well as supraventricular arrhythmias.
    • ¥ 1540
    5日内发货
    规格
    数量
  • Adaprolol maleate
    T71228121009-31-2
    Adaprolol maleate is a beta-blocker and opthalmic which may be used in the treatment of Glaucoma or other ailments of the eye. Adaprolol has marked electrophysiologic effects. Its major action was on sinus node; it prolonged the basic sinus cycle length and had significant effect on intrinsic automaticity as reflected by the prolonged corrected sinus node recovery time and sinuatrial conduction time. There was, also, direct effect on atrial function and AV nodal function. Adaprolol prolonged the effective refractory period of the His-Purkinje system and the ventricle. The potency of adaprolol's electrophysiologic effects are higher compared to other widely used beta-blockers. Adaprolol appears to be a potent beta-blocker with particularly strong antiarrhythmic effect and it would be very useful in the treatment of both supraventricular and ventricular tachyarrhythmias and ectopic beats.
    • ¥ 10600
    6-8周
    规格
    数量
  • Flecainide hydrochloride
    T858157415-44-8
    Flecainide hydrochloride 是一种用于预防和治疗异常快速心率的药物。这包括室性和室上性心动过速。
    • ¥ 247
    In stock
    规格
    数量
  • Nifekalant
    尼非卡兰, MS-551 free base
    T89560130636-43-0
    Nifekalant (MS-551) 作为一种III类抗心律不齐化合物,具体表现为IKr钾通道阻滞剂,其IC50值达到10 μM.它主要用于快速室上性心律失常的研究.
    • 待询
    10-14周
    规格
    数量
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