Fascaplysin is a cyclin D kinase 4 cyclin D1 inhibitor (IC50 = 0.35 μM). Fascaplysin induces caspase mediated crosstalk between autophagy and apoptosis through the inhibition of PI3K AKT mTOR signaling cascade in human leukemia HL-60 cells.
1beta-Hydroxyeuscaphic acid demonstrates notable hepatoprotective activity, effectively minimizing the leakage of intracellular enzymes, attenuating protein oxidation, and reducing apoptosis rates.
Bromopride hydrochloride is the salt form of Bromopride, a dopamine D2 receptor blocker. Bromopride exerts is a gastrointestinal prokinetic exploited clinically for the management of motor disorders of the upper gastrointestinal tract, including functional dyspepsia, gastric stasis of various origins and emesis.