oxidoreductase enzyme

1,4-D-Gulonolactone (D-Gulonic acid γ-lactone) (也称为还原性抗坏血酸，RAA) 是 L-gulono-1,4-lactone oxidoreductase (EC 1.1.3.8)的底物，催化植物和动物中l -抗坏血酸(维生素C)生物合成的最后一步。enzyme L-Gulono-1,4-lactone oxidase 在容易患坏血病、缺乏维生素c的动物(如人类)中缺失。1,4-D-Gulonolactone 存在于人体血液中，并被用作比较运动引起的氧化应激变化的标志物之一。

2,5-Furandicarboxylic acid (Dehydromucic Acid) 是重要的能够再生生物技术基础，能够在人类尿液中检测到，在聚酯生产中能够作为对苯二甲酸的环保替代品。

EPI-589, a quinone derivative and oxidoreductase enzyme inhibitor, is considered safe and well tolerated, showing promise for the treatment of amyotrophic lateral sclerosis (ALS).

VPC162134 是一种抗菌剂，能够抑制H. pylori、C. jejuni、MRSA和S. epidermidis，最低抑制浓度（MIC）分别为2.9、17.5、93.3和93.3 μM。此外，VPC162134 是丙酮酸铁氧还蛋白氧化还原酶 (PFOR) 的抑制剂。

Tretazicar (NSC-115829) 是一种抗肿瘤前药，由 NAD(P)H 醌氧化还原酶 2 激活。它在酶促活化后生成细胞毒性双功能烷基剂，可以形成 DNA-DNA 链间交联。

Caricotamide is a synthetic co-substrate that activates the human endogenous enzyme NRH:quinone oxidoreductase 2 (NQO2) with potential chemoadjuvant activity. When caricotamide is administered simultaneously with the prodrug tretazicar, NQO2 converts tretazicar to the bifunctional alkylating agent dinitrobenzamide, which is capable of forming a high degree of DNA interstrand cross-links, resulting in the inhibition of DNA replication and the induction of apoptosis. NQO2 has been found to be over-expressed in cancers such as hepatocellular carcinoma (HCC), colorectal and ovarian cancers.

L-Lactate dehydrogenase (LAD) 是一种厌氧代谢途径和糖代谢途径中的氧化还原酶，广泛存在于身体的各个组织中。

Glucose dehydrogenase (GDH)是一种氧化还原酶，催化β-D-葡萄糖氧化成β-D-葡糖酸-1,5-内酯，同时将辅助因子NADP+还原至NADPH，或以较小程度还原NAD+至NADH。此酶能接收NAD+和NADP+作为辅助因子，适用于NADH与NADPH的再生。

Fructosyl-peptide oxidase (FPOX-CE) (Fructosyl-peptide: oxygen oxidoreductase) 是一种酶，专门催化含糖肽的氧化反应。该酶对小分子糖化肽具有高活性，但未显示出对实验中常用的糖化六肽标准 fVHLTPE（用于 HbA1c 测量）的活性。Fructosyl-peptide oxidase (FPOX-CE) 在糖尿病监测研究应用中具有潜在价值。