non-sulfated

CCK (26-31) is an N-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety.

Hirudin (54-65; non-sulfated) is a desulfated peptide fragment of hirudin, an anticoagulant produced byH. medicinalis.1It inhibits fibrin clot formation induced by isolated bovine thrombin with an IC50value of 3.7 μM.2 1.Niehrs, C., Huttner, W.B., Carvallo, D., et al.Conversion of recombinant hirudin to the natural form by in vitro tyrosine sulfation. Differential substrate specificities of leech and bovine tyrosylprotein sulfotransferasesJ. Biol. Chem.265(16)9314-9318(1990) 2.Payne, M.H., Krstenansky, J.L., Yates, M.T., et al.Positional effects of sulfation in hirudin and hirudin PA related anticoagulant peptidesJ. Med. Chem.34(3)1184-1187(1991)

CCK (27-33) is a C-terminal fragment of CCK , a peptide hormone found in the intestine and brain that stimulates digestion, mediates satiety, and is involved in anxiety. Non-sulfated CCK (27-33) inhibits binding of [3H]naloxone in rat cerebellum membranes (IC50 = 4 uM) and inhibits electrically-stimulated contraction of isolated guinea pig ileum (IC50 = 17 uM), an effect that can be reversed by naloxone. Unlike sulfated CCK (27-33), the non-sulfated form does not reduce exploratory behavior in mice when administered at doses up to 1 uMol/kg.

CCK Octapeptide, non-sulfated acetate 是一种合成的胆囊收缩素脱硫酸肽。

Cholecystokinin Octapeptide, desulfated (CCK Octapeptide, non-sulfated) 是一种由8个氨基酸组成的胆囊收缩素-8。

Hirudin 是一种从水蛭中提取的，是一种凝血酶抑制剂，通过抑制 irf2 改善 Gsdmd 介导的细胞焦亡， 可用于研究糖尿病肾病。

Bivittoside A 是一种非硫酸化的六苷类化合物，从波氏海参中提取得到，具有抗真菌活性和潜在抗肿瘤活性。

Bivittoside B 是一种非硫酸化的六苷类化合物，从波氏海参中提取得到，具有抗真菌活性和潜在抗肿瘤活性。

Hyaluronan-binding peptide, biotin labeled 是通过 C 端 GGGSK 残基生物素化的透明质酸结合肽，能够干预 HA 与 CD44 受体的作用，并阻碍 T 细胞增殖。 HA 在细胞外基质和细胞表面广泛表达，参与多种生物过程，包括受精、胚胎发育、伤口修复、血管新生、炎症反应和肿瘤转移。

Hyaluronan-binding peptide, biotin labeled TFA 是一种具有生物活性的肽。(该肽通过 C 端 GGGSK 连接体实现生物素化，是透明质酸结合肽。透明质酸 (HA) 是在细胞外基质和细胞表面发现的非硫酸化糖胺聚糖。 HA 在受精、胚胎发育、伤口愈合、血管生成、白细胞向发炎组织运输和癌症转移中起作用。该肽已被证实可以阻断 HA 与 CD44 受体的结合并抑制 T 细胞增殖。)