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Search Results for " nkt "

Targets Recommended: Others

8

抑制剂 & 化合物

1

天然产物

11

重组蛋白

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Cat. No.	Product Name	Target	Signaling Pathways
T23345	SDZ NKT 343	Others	Others
	human tachykinin NK1 receptor antagonist
T11514	Gusperimus trihydrochloride NKT-01,BMS181173,Spanidin	Others	Others
	Gusperimus trihydrochloride is a derivative of the antitumor antibiotic spergualin with immunosuppressant activity.
T7633	Senktide	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Senktide 是速激肽NK3受体激动剂。
T7633L	Senktide acetate Senktide acetate(106128-89-6 free base)	Neurokinin receptor	GPCR/G Protein; Neuroscience
	Senktide acetate 是一种选择性速激肽 NK3 受体激动剂，促进 ELM 的巩固或表达，可用于研究阿尔茨海默症。
T36374	Naloxegol (NKTR-118)
	Naloxegol (NKTR-118; AZ-13337019) is an opioid-receptor antagonist[1]. [1]. Yoon SC, et al. Naloxegol in opioid-induced constipation: a new paradigm in the treatment of a common problem. Patient Prefer Adherence. 2017 Jul 24;11:1265-1271.
T35450	α-GalCer analog 8 α-GalCer analog 8,α-Galactosylceramide analog 8
	α-Galactosylceramide analog 8 (α-GalCer analog 8) is a triazole derivative of α-galactosylceramide. [1] It increases IL-2 secretion by DN32.D3 NKT hybridoma cells when co-cultured with CD1d-transfected RBL cells pre-loaded with α-GalCer analog 8 at a concentration of 32 ng/ml. α-GalCer analog 8 (32 ng/ml) induces IL-4 secretion to a greater extent than the synthetic α-GalCer KRN 7000 in mouse splenocytes in vitro and in mouse serum following administration of a 1 &#181g per animal dose, indicati...
T37604	ITK inhibitor
	Interleukin-2-inducible T cell kinase (ITK) is a non-receptor tyrosine kinase expressed in T cells, NKT cells and mast cells which plays a crucial role in regulating the T cell receptor (TCR), CD28, CD2, chemokine receptor CXCR4, and FcepsilonR-mediated signaling pathways. ITK inhibitors can be used for the treatment of inflammation and immune-mediated disorders. ITK inhibitor (N-[5-[[3-[(4-Acetylpiperazin-1-yl)carbonyl]-4-methyl-6-methoxy-phenyl]thio]thiazol-2-yl]-4-(N-1,2-dimethylpropylaminome...
T38008	KBC-007
	KBC-007 is a synthetic branched chain-containing analog of α-galactosylceramide (α-GalCer). It induces IL-4 and IFN-γ secretion by mouse splenocytes when used at a concentration of 0.5 ng/ml and IL-2 secretion by DN32.D3 NKT hybridoma cells co-cultured with CD1d-transfected RBL cells pre-loaded with KBC-007 at a concentration of 8 ng/ml. KBC-007 (1 μg per animal) increases levels of IL-4, but not IFN-γ, to a similar degree as α-GalCer in mouse serum. KBC-007 (0.5 μg per animal) increases the sur...

化合物

Cat.No: T23345

Target: Others

Gusperimus trihydrochloride

Cat.No: T11514

Synonym: NKT-01,BMS181173,Spanidin

Target: Others

Cat.No: T7633

Target: Neurokinin receptor

Senktide acetate

Cat.No: T7633L

Synonym: Senktide acetate(106128-89-6 free base)

Target: Neurokinin receptor

Naloxegol (NKTR-118)

Cat.No: T36374

α-GalCer analog 8

Cat.No: T35450

Synonym: α-GalCer analog 8,α-Galactosylceramide analog 8

Cat.No: T37604

Cat.No: T38008

Cat. No.	Product Name	Target	Signaling Pathways
T14193	α-Galactosylceramide KRN7000,α-GalCer	Others	Others
	α-Galactosylceramide (KRN7000) 是一种具有抗肿瘤和免疫刺激作用的合成糖脂。它是一种高效的 NKT 细胞激动剂，可与 CD1d 有效结合。它与 CD1d 的复合物可与 NKT 细胞的 T 细胞抗原受体结合。

天然产物

α-Galactosylceramide

Cat.No: T14193

Synonym: KRN7000,α-GalCer

Target: Others

Species：

Expression System：

Tag：

Cat. No.	Product Name	Species	Expression System
TMPY-02171	Cathepsin L Protein, Mouse, Recombinant (His) Ctsl1,1190035F06Rik,nkt,cathepsin L,MEP,fs	Mouse	HEK293 Cells
	Cathepsin L Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 37.3 kDa and the accession number is P06797.
TMPK-00043	IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated IL-21,白介素,Interleukin-21,白细胞介素,CVID11,Za11	Human	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 18.30 kDa and the accession number...
TMPK-00107	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled NKG2D,KLR,CD314,D12S2489E,NKG2-D	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled is expressed in HEK293 mammalian cells with N-hFc-Flag tag. The predicted molecular weight is 43.4 kDa and the a...
TMPK-00105	NKG2D/CD314 Protein, Human, Recombinant (His & Avi) NKG2-D,KLR,CD314,NKG2D,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.0 kDa and the accession number ...
TMPK-01105	IL-22RA1 Protein, Human, Recombinant (hFc) IL-22R-alpha-1,CRF2-9,IL-TIF-R1,IL-22R-α-1,IL22R1,zcytoR11,I...	Human	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPJ-01316	IL-21 Protein, Mouse, Recombinant (His) 白细胞介素,IL-21,Interleukin-21,白介素,IL21	Mouse	E. coli
	Interleukin-21(IL-21) is an approximately 14 kDa cytokine which belongs to the IL-15/IL-21 family. Mature mouse IL-21 shares 66%,59%, 58%, and 88% aa sequence identity with mature canine, human, rabbit, and rat IL-21, respectively. IL-21 is produced by activated T follicular helper cells (Tfh), Th17 cells, and NKT cells. It exerts its biological effects through a heterodimeric receptor complex (IL-21 specific IL-21 R). IL-21 is a cytokine that has potent regulatory effects on cells of the immun...
TMPK-00106	NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated NKG2D,NKG2-D,KLR,CD314,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with N-His-Avi tag. The predicted molecular weight is 19.0 kDa and the acc...
TMPK-01172	IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated 白介素,Interleukin-21,IL-21,Za11,CVID11,白细胞介素	Mouse	E. coli
	Interleukin-21 (IL-21), produced predominantly by CD4 T cells and natural killer T (NKT) cells, is a newly discovered member of the common γ-chain family of cytokines. It has been implicated in many immunological processes and has been linked to autoimmune diseases, allergies and other inflammatory diseases. IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated is expressed in E. coli expression system with N-His-Avi tag. The predicted molecular weight is 17.9 kDa and the accession number ...
TMPK-00108	NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag) NKG2D,NKG2-D,CD314,KLR,D12S2489E	Human	HEK293 Cells
	NKG2D is a type II transmembrane glycoprotein having an extracellular lectin-like domain. This domain lacks the recognizable calcium-binding sites found in true C-type lectins and binds protein rather than carbohydrate ligands. Human NKG2D is expressed on CD8 alpha beta T cells, gamma δ T cells, NK cells and NKT cells. NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag) is expressed in HEK293 mammalian cells with N-hFc-Flag tag. The predicted molecular weight is 43.4 kDa and the accession numbe...
TMPK-01071	IL-22RA1 Protein, Mouse, Recombinant (hFc) IL-22R α1,IL22R,zcytoR11,IL-TIF-R1,CRF2-9,IL-22R-alpha-1,IL-...	Mouse	HEK293 Cells
	Interleukin (IL)-22 is a member of the IL-10 family of cytokines and represents an important effector molecule of activated Th22, Th1, and Th17 cells, as well as Tc-cell subsets, gammadelta T cells, natural killer (NK), and NKT cells. IL-22 mediates its effects via a heterodimeric transmembrane receptor complex consisting of IL-22R1 and IL-10R2 and subsequent Janus kinase-signal transducers and activators of transcription (JAK-STAT) signaling pathways including Jak1, Tyk2, and STAT3. IL-22RA1 Pr...
TMPY-01674	CRTAM Protein, Human, Recombinant (His) cytotoxic and regulatory T cell molecule,CD355	Human	HEK293 Cells
	Cytotoxic and regulatory T-cell molecule, also known as Class-I MHC-restricted T-cell-associated molecule and CRTAM, is a single-pass type I membrane protein which belongs to thenectin family.CRTAM contains oneIg-like C2-type (immunoglobulin-like) domain and oneIg-like V-type (immunoglobulin-like) domain. In the immune system, the expression of CRTAM is restricted to activated class-I MHC-restricted cells, including NKT and CD8 cells. It is strongly expressed in spleen, thymus, small inte...

重组蛋白

Cathepsin L Protein, Mouse, Recombinant (His)

Cat.No: TMPY-02171

Species: Mouse

Expression System: HEK293 Cells

IL-21 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00043

Species: Human

Expression System: E. coli

NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag), FITC-Labeled

Cat.No: TMPK-00107

Species: Human

Expression System: HEK293 Cells

NKG2D/CD314 Protein, Human, Recombinant (His & Avi)

Cat.No: TMPK-00105

Species: Human

Expression System: HEK293 Cells

IL-22RA1 Protein, Human, Recombinant (hFc)

Cat.No: TMPK-01105

Species: Human

Expression System: HEK293 Cells

IL-21 Protein, Mouse, Recombinant (His)

Cat.No: TMPJ-01316

Species: Mouse

Expression System: E. coli

NKG2D/CD314 Protein, Human, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-00106

Species: Human

Expression System: HEK293 Cells

IL-21 Protein, Mouse, Recombinant (His & Avi), Biotinylated

Cat.No: TMPK-01172

Species: Mouse

Expression System: E. coli

NKG2D/CD314 Protein, Human, Recombinant (hFc & Flag)

Cat.No: TMPK-00108

Species: Human

Expression System: HEK293 Cells

IL-22RA1 Protein, Mouse, Recombinant (hFc)

Cat.No: TMPK-01071

Species: Mouse

Expression System: HEK293 Cells

CRTAM Protein, Human, Recombinant (His)

Cat.No: TMPY-01674

Species: Human

Expression System: HEK293 Cells

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