mtp

MTP作为一种PKM2抑制剂，能够通过激活caspase-3来诱导癌细胞发生凋亡（apoptosis），同时诱导自噬（autophagy）过程并提高ROS的产生量。此外，MTP对JAK2信号传递通路也有抑制作用。该化合物主要用于研究口腔鳞状细胞癌。

Dirlotapide (CP742033) 是一种肠道选择性微粒体甘油三酯转移蛋白(MTP)抑制剂。它可以减轻糖尿病狗的体重。Dirlotapide 以剂量依赖性方式减少食物摄入量，可能是通过增加 肽YY 释放到循环中。

BMS-212122 (UNII-0Z473OO6GB) 是一种有效的微粒体甘油三酯转移蛋白(MTP )抑制剂，在动物实验中显示出降血脂作用。BMS-212122 显著减少动脉粥样硬化斑块中的脂质含量和单核细胞衍生(CD68+)细胞。

Granotapide 是一种微粒体甘油三酯转移蛋白（MTP）抑制剂，治疗和而预防动脉硬化，冠状动脉疾病，代谢综合征，肥胖，糖尿病，糖尿病前期和高血压。

Lomitapide (AEGR-733) 是一种高效的微粒体甘油三酯转移蛋白(MTP)抑制剂，体内试验的IC50值为8 nM。

CP-319340 free base is a inhibitor of microsomal triglyceride transfer protein (MTP) .

Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).

PF-02575799 is an inhibitor of microsomal triglyceride transfer protein (MTP) (IC50: 0.77±0.29 nM).

Lomitapide Mesylate (BMS-201038 mesylate) 是一种高效MTP 蛋白抑制剂，其体外IC50值为8 nM。

KD-026 (SLx 4090) 是具有口服活性的、肠细胞特异性的微粒体甘油三酯转移蛋白 (MTP)抑制剂，IC50为 8.0 nM。KD-026 (SLx 4090) 在糖尿病2型中有研究的价值。

Implitapide Racemate is the racemate of Implitapide. Implitapide is an inhibitor of microsomal triglyceride transfer protein (MTP).

CP-346086 dihydrate is a potent and orally active inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM for both human and rodent MTP. This compound effectively lowers plasma cholesterol and triglyceride levels in vivo.

CP-346086 is a highly potent and orally bioavailable inhibitor of microsomal triglyceride transfer protein (MTP), exhibiting an IC50 value of 2.0 nM against both human and rodent MTP. This compound effectively reduces plasma levels of cholesterol and triglycerides when administered in vivo.

PROTACMTP3 degrade-1 是一种用于降解MYC的PROTAC降解剂。

Mifamurtide is a drug against osteosarcoma, is an immunomodulator with antitumor effects.

Methional 是食品中甲硫氨酸通过Strecker降解的主要产物，作为反应物参与氧化偶联、炔烃羰基化等反应，并可作为乙烯生物合成前体。

Mifamurtide protects mice against herpes simplex virus type 2. It also is a macrophage activator.

Mifamurtide sodium is a drug against osteosarcoma, a kind of bone cancer mainly affecting children and young adults. It was approved in Europe in March 2009.

MTPPA (M 5011) 是一种具有抗炎症和疼痛作用的化合物。

Group II/group III metabotropic glutamate receptor antagonist

IMTPPE inhibits transcriptional activity and protein level of AR in C4-2 prostate cancer cells. It also inhibits AR-target gene expression.

CM-TPMF是一种高效和潜在的K(Ca)2.1通道激活剂,(−)-CM-TPMF的EC50值为24 nM，通过跨膜第5段的Ser293发挥激活作用，可用于研究相关神经障碍疾病。

IHMT-PI3K-315 (20e) 作为一种选择性和高效的PI3Kγ/δ抑制剂，其对PI3Kγ的IC50值为4.0 nM，而对PI3Kδ的IC50值则为9.1 nM。该化合物显著具备抗肿瘤活性。

M-5011 is a non-steroidal anti-inflammatory drug and immunomodulator potentially for the treatment of inflammation and pain. M-5011 had an effective antinociceptive activity (ED50 value) of 0.63 mg/kg. M-5011 partially inhibits the generalized bone loss a