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顶部产品介绍抗原信息化学信息储存和溶解信息计算器

Anti-COMT Polyclonal Antibody

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货号 TMAB-04553

Anti-COMT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 COMT。Anti-COMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

Anti-COMT Polyclonal Antibody

Anti-COMT Polyclonal Antibody

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Rating icon 还可以
货号 TMAB-04553

Anti-COMT Polyclonal Antibody 是一种 Rabbit 抗体，靶向 COMT。Anti-COMT Polyclonal Antibody 可用于 IHC-P,IHC-Fr,IF。

规格价格库存数量
50 μL
¥ 1,170
5日内发货
100 μL
¥ 1,975
5日内发货
200 μL
¥ 2,790
5日内发货
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产品介绍

生物活性
产品描述
Anti-COMT Polyclonal Antibody is a Rabbit antibody targeting COMT. Anti-COMT Polyclonal Antibody can be used in IHC-P,IHC-Fr,IF.
Ig Type
IgG
反应种属
Mouse,Rat (predicted:Human,Pig,Cow,Horse)
应用IHC-PIHC-FrIF
推荐剂量
IHC-P: 1:100-500; IHC-Fr: 1:100-500; IF: 1:100-500
抗体种类
Polyclonal
宿主来源Rabbit
亚细胞定位Isoform Soluble: Cytoplasm.Isoform Membrane-bound: Cell membrane; Single-pass type II membrane protein; Extracellular side.
组织特异性Brain, liver, placenta, lymphocytes and erythrocytes.
构建方式Hybridoma Polyclonal Antibody
纯化方式Protein A purified
性状Liquid
缓冲液0.01M TBS (pH7.4) with 1% BSA, 0.02% Proclin300 and 50% Glycerol.
浓度1mg/ml
研究背景Catechol-O-methyltransferase catalyzes the transfer of a methyl group from S-adenosylmethionine to catecholamines, including the neurotransmitters dopamine, epinephrine, and norepinephrine. This O-methylation results in one of the major degradative pathways of the catecholamine transmitters. In addition to its role in the metabolism of endogenous substances, COMT is important in the metabolism of catechol drugs used in the treatment of hypertension, asthma, and Parkinson disease. COMT is found in two forms in tissues, a soluble form (S-COMT) and a membrane-bound form (MB-COMT). The differences between S-COMT and MB-COMT reside within the N-termini. Several transcript variants are formed through the use of alternative translation initiation sites and promoters. [provided by RefSeq, Sep 2008]
抗原信息
免疫原
KLH conjugated synthetic peptide: human COMT
抗原种属
Human
基因名称
COMT
基因ID
1312
蛋白名称
Catechol O-methyltransferase
Uniprot ID
P21964
功能
Catalyzes the O-methylation, and thereby the inactivation, of catecholamine neurotransmitters and catechol hormones. Also shortens the biological half-lives of certain neuroactive drugs, like L-DOPA, alpha-methyl DOPA and isoproterenol.
化学信息
分子量Theoretical: 30 kDa.
储存&溶解度
储存方式Store at 2°C-8°C for 1 month. Store at -20°C or -80°C for 12 months. Avoid repeated freeze-thaw cycles.
运输方式Shipping with blue ice.
存储store at low temperature | -20°C for 1 year

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