Metalaxyl-M ((R)-Metalaxyl), the active (R)-enantiomer of Metalaxyl, is a broad-spectrum fungicide that targets protein and ribosomal RNA synthesis in fungi. It is employed in the research of plant diseases attributed to pathogens from the Oomycota division.
Capreomycin is a polypeptide antibiotic originally isolated from S. capreolus. It is active against M. tuberculosis (MIC = 10 µg ml). Capreomycin binds to both the 30S and 50S ribosomal subunits, inhibiting protein synthesis.
Valnemulin, a broad-spectrum pleuromutilin antibiotic, targets peptidyl transferase within the 50S ribosomal subunit, effectively used in veterinary medicine to address swine diseases such as B. hyodysenteriae and M. hyopneumoniae.