ilex

Ilexgenin A 是一种五环三萜类化合物，提取自海南冬青，可用于研究炎症及癌症。

Candesartan Cilexetil (TCV-116) 是一种血管紧张素II 拮抗剂，可用于治疗高血压。

Ilexsaponin A (Ilexsaponin A1)1 是分离自冬凌草的根中，利用抗凋亡途径减轻缺血再灌注引起的心肌损伤。它能够减少心肌梗塞的大小，减少 LDH，AST 和 CK-MB 的血清水平，促进细胞活力并抑制缺氧 复氧心肌细胞的凋亡。

Ilexoside D has ant-allergic, and anti-coagulant activities, it shows anti-tissue factor activity as well as the antithrombotic activity.

Ilexoside O, a triterpene saponin derived from Ilex pubescens roots, demonstrates modest inhibition of xanthine oxidase (XOD) activity with an IC50 value of 53.05 μM.

Ilexoside XLVIII为一种三萜皂苷，自苦冬青叶片水提物分离而得，功能为抑制酰基辅酶A胆固醇酰基转移酶（ACAT）。

Ilexhainanoside D is a natural product from Periploca sepiumBge.

Ilexoside K is a natural product from Ilex pubescens.

Ilexgenin B is a natural product from Ilex chinensis Sims

Ilexside I 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T124123。

1H-1-ethyl Candesartan Cilexetil 是 Candesartan cilexetil 批量合成中的一种工艺相关杂质，坎地沙坦酯是一种强效、长效和选择性血管紧张素 II 1 型受体 (AT1) 拮抗剂。

Brassilexin is a cyclobrassinin hydrolase inhibitor, a unique enzyme from the fungal pathogen Alternaria brassicicola.

Trilexium (TRX-E-009-1)，一种第三代苯并吡喃，其结构与 TRX-E-002-1 相似。此化合物能提升 p21 蛋白的表达，并诱导细胞凋亡(apoptosis)。同时，Trilexium 亦具有解聚微管的作用，并展示出广泛的抗癌活性。

Ilexsaponin B2 是一种天然产物，可用于生命科学领域的相关研究。其产品编号为 TJS0502，CAS号为 108906-69-0。

Caulilexin C 是一种来自十字花科植物的植物抗毒素，具有抗真菌活性。

3-Oxo-alpha-ilexanolic acid 是一种天然化合物，可作为天然产物对照品。

Eriodictyol (Huazhongilexone) 是从中草药中得到的一种黄酮类天然产物，具有抗氧化、抗炎和抗糖尿病作用。它还是一种流感依赖 RNA 的RNA 聚合酶抑制剂，IC50为 18 nM。它可诱导Nrf2信号通路。

11-oxo-alpha-amyrin (Neoilexonol) 是一种从Leonurus japonicus (Lamiaceae) 提取出的三萜化合物，是一种天然化合物 。

Rotundic acid (Rutundic acid) 是一种从圆形肠球菌中获得的三萜类天然产物，具有抗炎和保护心脏的能力。它可通过 AKT mTOR 和 MAPK 途径在肝细胞癌中诱导 DNA 损伤和细胞凋亡。

Pedunculoside 是从 Ilex rotunda Thunb 中提取的，通过对脂质形成和脂肪酸 β-氧化的调节而发挥降脂作用。

20-hydroxy Arachidic acid is a hydroxylated fatty acid that has been found in the suberin component of silver birch (B. pendula) outer bark as well as the leaves, roots, and wood of Q. ilex from Cala Violina and Colognole, Italy. 20-hydroxy Arachidic acid was identified as a potential inhibitor of human rhinovirus coat protein in a structure-based virtual screen.

Methyl 3,4-dihydroxyphenylacetate is a polyphenol that has been found inI. aquifoliumseeds and has antioxidant and antiviral activities.1,2It scavenges 2,2-diphenyl-1-picrylhydrazyl radicals in a cell-free assay (IC50= 0.0025 mg ml).1Methyl 3,4-dihydroxyphenylacetate (0.01 μg ml) inhibits enterovirus 71 replication in rhabdomyosarcoma cells.2 1.Nahar, L., Russell, W.R., Middleton, M., et al.Antioxidant phenylacetic acid derivatives from the seeds of Ilex aquifoliumActa Pharm.55(2)187-193(2005) 2.Wang, L., Wang, J., Wang, L., et al.Anti-enterovirus 71 agents of natural productsMolecules20(9)16320-16333(2015)

Ursolic acid acetate (Acetylursolic acid) 分离于 Ficus microcarpa 的气根中，对 KB 细胞显示细胞毒性(IC50:8.4 μM)。

5-O-(3'-O-Glucosylcaffeoyl)quinic acid (compound 19) is a phenolic compound primarily located in the leaves of Ilex glabra L. Gray (Aquifoliaceae).