gcpii-in-1

GCPII-IN-1 is a potent inhibitor scaffold targeting glutamate carboxypeptidase II (GCPII), also known as prostate-specific membrane antigen (PSMA). It exhibits a high affinity for GCPII, with a binding affinity (K i ) of 44.3 nanomolar (nM).

GCPII-IN-1 TFA (compound 2)是一种谷氨酸羧肽酶 II(GCPII,glutamate carboxypeptidase II，PSMA)的抑制剂支架，Ki=44.3±2.4 nM，能够与生物素结合蛋白或纳米颗粒连接并靶向表达GCPII的细胞，可用于前列腺癌。