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  • ALK
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alk/ros1-in-1

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    TargetMol | Inhibitors_Agonists
  • ALK/ROS1-IN-1
    T102862365497-07-8In house
    ALK/ROS1-IN-1 is a potent and selective anti-crizotinib-resistant ALK/ROS1 dual inhibitor (IC50s: 0.530 μM and 0.174 μM for ROS1 and ALK enzyme).
    • ¥ 10600
    8-10周
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  • PF-06463922 acetate
    T700601924207-18-0
    PF-06463922 acetate is a potent, selective brain-penetrable inhibitor of both anaplastic lymphoma kinase (ALK) and c-ros Oncogene 1 (ROS1) with strong activity against all known ALK and ROS1 mutants identified in patients with crizotinib-resistant disease. PF-06463922 is in clinical trials for the treatment of non–small cell lung cancer (NSCLC).
    • ¥ 17200
    10-14周
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