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86

抑制剂 & 化合物

11

天然产物

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Cat. No.	Product Name	Target	Signaling Pathways
T12941	SN 2	TRP/TRPV Channel	Membrane transporter/Ion channel
	SN 2 是TRPML3离子通道的有效激活剂，EC50为 1.8 μM。它对登革热病毒 2 和寨卡病毒具有有效的抑制作用。
T10022	1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine	Endogenous Metabolite	Metabolism
	1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine 是一种人内源性代谢产物。
T19105	2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol	Others	Others
	2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol is a triglyceride.
T0942	Quinacrine dihydrochloride 疟疾平,Mepacrine dihydrochloride,阿的平,SN-390,Quinacrine 2HCl	Apoptosis; Mitophagy; DNA; Phospholipase; Parasite; Autophagy; Histamine Receptor	Apoptosis; Autophagy; DNA Damage/DNA Repair; GPCR/G Protein; Immunology/Inflammation; Metabolism; Microbiology/Virology; Neuroscience
	Quinacrine dihydrochloride (Mepacrine dihydrochloride) 是一种具有口服活性的抗疟剂，抑制 NF-κB 并激活 p53 信号转导，诱导肿瘤细胞发生凋亡，具有抗肿瘤和抗寄生虫活性。
T35482	1-Palmitoyl-2-hydroxy-sn-glycero-3-PE 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine
	1-Palmitoyl-2-hydroxy-sn-glycero-3-PE is a naturally-occurring lysophospholipid. [1] It inhibits the growth of L. donovani promastigotes (GIC50 = 8 uM). [2]1-Palmitoyl-2-hydroxy-sn-glycero-3-PE serum levels are decreased in a mouse model of alcohol-induced liver injury and in a hepatocellular carcinoma mouse xenograft model. [3] Human serum levels are also decreased immediately and 14 hours following an exercise regimen of 2.5 hours of running for three days. [1]1-Palmitoyl-2-hydroxy-sn-glycero-...
T40972	1-Oleoyl-2-acetyl-sn-glycerol
	1-Oleoyl-2-acetyl-sn glycerol, a synthetic, cell-permeable diacylglycerol analog, activates calcium-dependent protein kinase C (PKC) and induces superoxide production.
T40757	1-Stearoyl-2-arachidonoyl-sn-glycerol
	1-Stearoyl-2-arachidonoyl-sn-glycerol, a diacylglycerol (DAG) encompassing polyunsaturated fatty acids, possesses the ability to activate PKC. Moreover, this compound has the potential to enhance nonselective cation channel (NSCC) activity.
T38218	1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC
	1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 是一种在生物膜中的磷脂，在 sn-1 和 sn-2 位置分别含有硬脂酸和二十二碳六烯酸。它已被用于研究脂膜的组织和动力学。在超氧化物歧化酶 1 突变体转基因小鼠肌萎缩性脊髓侧索硬化症（ALS）模型中1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 的水平在疾病晚期会在 L5 前角下降。1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC 可用于研究生物膜。
T36453	1-Myristoyl-2-hydroxy-sn-glycero-3-PE
	1-Myristoyl-2-hydroxy-sn-glycero-3-PE is a naturally occurring lysophospholipid. It induces transient increases in intracellular calcium in PC12 cells. Serum levels of 1-myristoyl-2-hydroxy-sn-glycero-3-PE are elevated in patients with malignant breast cancer compared to healthy controls.
T38217	1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE
	1-Stearoyl-2-adrenoyl-sn-glycero-3-PE is a phospholipid that contains stearic acid and adrenic acid at thesn-1 andsn-2 positions, respectively. 1-Stearoyl-2-adrenoyl-sn-glycero-3-PE levels are inversely correlated with subject age in mitochondria isolated from human post-mortem hippocampus.1 1.Hancock, S.E., Friedrich, M.G., Mitchell, T.W., et al.Decreases in phospholipids containing adrenic and arachidonic acids occur in the human hippocampus over the adult lifespanLipids50(9)861-872(2015)
T35489	1-O-Octadecyl-2-O-methyl-sn-glycerol
	1-O-Octadecyl-2-O-methyl-sn-glycerol is a metabolite of a phosphotidylinositol ether lipid analog (PIA). PIAs are known to target the pleckstrin homology domain of the serine/threonine kinase Akt and to induce apoptosis in cancer cell lines with high levels of endogenous Akt activity.
T10030	1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine	Others	Others
	1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine is an endogenous metabolite.
T37485	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC
	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO).
T37486	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC
	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PC by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC is toxic to human umbilical vein endothelial cells (HUVECs) when used at a concentration of 100 μM.
T37487	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE
	1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HpETE at the sn-2 position. It is produced via oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-lipoxygenase (15-LO). 1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE (0.6 and 0.9 μM) increases ferroptotic cell death in wild-type and Acsl4 knockout Pfa1 mouse embryonic fibroblasts (MEFs) treated with the GPX4 inhibitor RSL3.
T37284	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE
	1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE is a phospholipid that contains stearic acid at the sn-1 position and 15(S)-HETE at the sn-2 position. It is formed in human peripheral monocytes activated by the calcium ionophore A23187 by direct oxidation of 1-stearoyl-2-arachidonoyl-sn-glycero-3-PE by 15-LO. Phosphoethanolamine (PE) HETEs (PE-HETEs), including 1-stearoyl-2-15(S)-HETE-sn-glycero-3-PE, are the main source of esterified HETE in ionophore-activated monocytes.
T10029	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine	Endogenous Metabolite	Metabolism
	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine 是内源性代谢产物的一种。
T72929	18:0-22:6 DG 1-Stearoyl-2-docosahexaenoyl-sn-glycerol
	18:0-22:6 DG (1-Stearoyl-2-docosahexaenoyl-sn-glycerol) 是一种二酰基甘油，可以与RasGRP 结合并调节MAP 激酶活化。
T10832	CL2-SN-38	Others	Others
	CL2-SN-38, a part of the antibody-drug conjugate (ADC), can conjugate with the anti-Trop-2-humanized antibody hRS7. SN-38 is an inhibitor of DNA topoisomerase I.
T83772	1-Linoleoyl Lysophosphatidic Acid sodium 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA
	1-Linoleoyl LPA（1-亚油酰LPA）是LPA2受体的激动剂，属于一种含有亚油酸的甘油磷脂，在sn-1位置含亚油酸。它是小鼠和人体血浆中最丰富的LPA。1-Linoleoyl LPA在表达LPA2受体的Sf9细胞中选择性地增加细胞内钙水平（EC50约为10 nM），相较于表达LPA1和LPA3受体的Sf9细胞（EC50分别约为200和80 nM）。携带NCTC克隆2472肿瘤的小鼠中，1-linoleoyl LPA的血清水平增加。与患有初发进行性多发性硬化症的患者相比，复发缓解型多发性硬化症患者的血浆1-Linoleoyl LPA水平降低，且与神经功能缺损严重程度负相关。
T81895	Lysophosphatidylcholine C19:0 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
	Lysophosphatidylcholine C19:0 (1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine)为具有C19:0酰基链的脂质。该化合物能促进IL-1beta的分泌。
T81216	SAPE 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylethanolamine
	SAPE（1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylethanolamine）为R-Phycoerythrin标记的Streptavidin荧光探针。该探针与生物素结合时可应用于肿瘤检测，具备高敏感性与广泛的检测范围。
T69626	L6H21
	L6H21 is an inhibitor of the interaction and signaling transduction of LPS-TLR4/MD-2 (myeloid differentiation 2).
T71755	QNN33358
	QNN33358 is an alkylacylglycerol acts as a protein kinase C (PKC) inhibitor and diacylglycerol (DAG) antagonist.
T83422	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine
	1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine 是一种由磷酸甘油、胆碱和棕榈酸构成的甘油磷酸胆碱类化合物，通常在体内氧化应激位点累积。该化合物是 B 类清道夫受体 (CD36和SR-BI) 的有效配体，特别是氧化磷脂 oxPC(CD36)。此外，氧化磷脂 (oxPLs) 在肿瘤细胞凋亡中扮演关键角色，并且在恶性胆管狭窄疾病中可能会有所增加。
T74027	1-Palmitoyl-2-oleoyl-sn-glycerol
	1-Palmitoyl-2-oleoyl-sn-glycerol是HIF (藻殖段诱导因子)-1中的主要二酰基甘油，属于内源性代谢产物。
T67131	1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine
	1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine 是一种有用的有机化合物，可用于生命科学领域的相关研究，其产品编号为 T67131。
T75688	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol
	1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol 是一种内源性代谢物，是细胞膜成分。
T64546	1-Stearoyl-2-myristoyl-sn-glycero-3-PC
	1-Stearoyl-2-myristoyl-sn-glycero-3-PC 是一种有用的有机化合物，可用于生命科学领域的相关研究。其产品编号为 T64546，CAS号为 20664-02-2。
T83423	1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine
	1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine 是一种荧光探针，其极性磷脂酰乙醇胺头基适用于测定脂蛋白与血浆表面脂质的氧化。
T74179	1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine
	1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine，一种血液中的内源性代谢物，主要用于妊娠和败血症的研究。
T77230	1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine
	1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine为存在于尿中的内源性代谢物，用于肥胖研究。
T63847	1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium
	Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium (18:1 Lyso-PS) 是一种改性 PS 产品，经由 NADPH 氧化酶激活及 Lyso-PS 信号转导后得到。Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium 能够利用巨噬细胞 G2A 功能，增强现有的受体/配体系统，进而解决中性粒细胞炎症。
T38140	Phosphatidylethanolamine from bovine
	Phosphatidylethanolamines (bovine) 是从牛脑中分离出来的一种磷脂酰乙醇胺混合物，在 sn-1 和 sn-2 位置上带有不同的脂肪酰基。Phosphatidylethanolamines (bovine) 是在原核生物、哺乳动物、植物和酵母细胞膜中含量均很高的磷脂，约占哺乳动物磷脂总量的 25%。
T37706	1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol
	1,3-Dipalmitoyl-2-octanoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and octanoic acid at the sn-2 position.
T36079	Tripelargonin
	Tripelargonin is a triacylglycerol that contains nonanoic acid at the sn-1, sn-2, and sn-3 positions. It has been found in Schizochytrium biomass.1 Tripelargonin increases blood levels of the ketone body D-(-)-3-hydroxybutyrate in newborn rhesus monkeys.2
T37623	1,2-Dierucoyl-sn-glycero-3-PC
	1,2-Dierucoyl-sn-glycero-3-PC is a phospholipid containing erucic acid at the sn-1 and sn-2 positions. It has been used in the study of lipid membranes and to determine the effect of long-chain phospholipids on the secondary structure of human islet amyloid polypeptide (hIAPP).
T37125	1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol
	1,3-Dipalmitoyl-2-eicosapentaenoyl-rac-glycerol is a triacylglycerol that contains palmitic acid at the sn-1 and sn-3 positions and eicosapentaenoic acid at the sn-2 position. Dietary administration of 1,3-dipalmitoyl-2-eicosapentaenoyl-rac-glycerol decreases hepatic triacylglycerol levels in mice.
T37383	1,2,3-Trilinoelaidoyl-rac-glycerol
	1,2,3-Trilinoelaidoyl-rac-glycerol is a triacylglycerol that contains linoelaidic acid at the sn-1, sn-2, and sn-3 positions. Dietary administration of 1,2,3-trilinoelaidoyl-rac-glycerol (0.6-6.3% w/w) lowers serum levels of thromboxane B2 , prostaglandin F2 (PGF2), and PGE in rats.1 \|1. Bruckner, G., Goswami, S., and Kinsella, J.E. Dietary trilinoelaidate: Effects on organ fatty acid composition, prostanoid biosynthesis and platelet function in rats. J. Nutr. 114(1), 58-67 (1984).
T27811	LEI-106
	LEI-106, a novel potent sn-1 DAGLalpha inhibitor, blocks the hydrolysis of sn-1-oleoyl-2-AG, inhibits the hydrolysis of 2-AG by the monoacylglycerol lipase ABHD6.
T38216	1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol
	1-Palmitoyl-2-oleoyl-3-arachidonoyl-rac-glycerol is a triacylglycerol that contains palmitic acid , oleic acid , and arachidonic acid at the sn-1, sn-2, and sn-3 positions, respectively. It has been found in lipid extracts from whole rat retina.1
T77824	Sacituzumab govitecan IMMU-132
	Sacituzumab govitecan (IMMU-132)是一种针对Trop-2的抗体-活性分子偶联物(ADC)，其通过传递SN-38发挥抗癌活性。
T37122	1,2-Dilinoleoyl-sn-glycerol
	1,2-Dilinoleoyl-sn-glycerol is a diacylglycerol (DAG) with linoleic acid (18:2) side chains attached at both the sn-1 and sn-2 positions. It has been found as a component of phosphatidic acid in rat liver mitochondria and in spinach chloroplast membranes. 1,2-Dilinoleoyl-sn-glycerol is upregulated in some pregnant women and has been used as a biomarker to predict later preeclampsia in early pregnancy.
T38358	1,3-Distearoyl-2-Oleoyl-rac-glycerol
	1,3-Distearoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains stearic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. It has been found in Kpangnana, Chinese tallow, and cocoa butters. 1,3-Distearoyl-2-oleoyl-rac-glycerol increases the phagocytic function of reticulo-endothelial cells in mice when administered at doses of 5 and 10 mg per animal.
T35443	1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol
	1-Palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol is a triacylglycerol that contains palmitic , stearic , and oleic acid at the sn-1, sn-2, and sn-3 positions, respectively. It has been detected in RAW 264.7 cells by neutral loss MS. Increased serum levels of 1-palmitoyl-2-stearoyl-3-oleoyl-rac-glycerol are a potential biomarker for non-alcoholic fatty liver disease (NAFLD).
T17730	CL2 Linker	Others	Others
	CL2 Linker is a cleavableADC linker. CL2-SN-38 and CL2A-SN-38 are equivalent in drug substitution (~6), cell binding (Kd ~1.2 nM), cytotoxicity (IC50 ~2.2 nM), and serum stability in vitro (t1/2 ~20 hours)[1][2].
T35441	Tripalmitolein
	Tripalmitolein is a triacylglycerol that contains palmitoleic acid at the sn-1, sn-2, and sn-3 positions. It reduces red blood cell deformability in a concentration-dependent manner in a Reid's filtration assay. Hepatic levels of 1,2,3-tripalmitoleoyl-rac-glycerol are increased in the JAK2L mouse model of hepatic steatosis. Tripalmitolein plasma levels are decreased in renal patients before dialysis.
T19145	4'-Methoxyflavonol	Others	Others
	4'-Methoxyflavonol is a flavone/flavonol compound that has been synthetically produced. It exhibits a structure with 1, 2-dipalmitoyl-sn-glycero-3-phosphocholine (DPPC) bilayers.
T36005	1-Oleoyl-2-Palmitoyl-rac-glycerol
	1-Oleoyl-2-palmitoyl-rac-glycerol (1,2-OP) is a diacylglycerol containing oleic acid at the sn-1 position and palmitic acid at the sn-2 position. It enhances the inhibition of superoxide anion production by cytochalasin B when used at a concentration of 10 μM. The concentration of 1,2-OP decreases from 25.7 to 11.15% during the dry-curing process of Iberian ham.
T37123	1,2-Dioctanoyl PC
	Phosphatidylcholine (PC) species are a common class of phospholipids that comprise the mammalian cell membrane. 1,2-Dioctanoyl PC is a synthetic analog of natural phosphatidylcholine species containing saturated C8:O fatty acids in the sn-1 and sn-2 positions of the glycerol backbone. It exhibits a critical micelle concentration (CMC) value of 0.25 mM at 27°C. 1,2-Dioctanoyl PC serves as an efficient substrate for phospholipase D (PLD) as well as sPLA2 isozymes from bovine pancreas and bee venom...

化合物

Cat.No: T12941

Target: TRP/TRPV Channel

1-Myristoyl-2-stearoyl-sn-glycero-3-phosphocholine

Cat.No: T10022

Target: Endogenous Metabolite

2-γ-Linolenoyl-1,3-dilinoleoyl-sn-glycerol

Cat.No: T19105

Target: Others

Quinacrine dihydrochloride

Cat.No: T0942

Synonym: 疟疾平,Mepacrine dihydrochloride,阿的平,SN-390,Quinacrine 2HCl

Target: Apoptosis, Mitophagy, DNA, Phospholipase, Parasite, Autophagy, Histamine Receptor

1-Palmitoyl-2-hydroxy-sn-glycero-3-PE

Cat.No: T35482

Synonym: 1-Palmitoyl-2-hydroxy-sn-glycero-3-PE,1-Hexadecanoyl-sn-glycero-3-Phosphoethanolamine

1-Oleoyl-2-acetyl-sn-glycerol

Cat.No: T40972

1-Stearoyl-2-arachidonoyl-sn-glycerol

Cat.No: T40757

1-Stearoyl-2-docosahexaenoyl-sn-glycero-3-PC

Cat.No: T38218

1-Myristoyl-2-hydroxy-sn-glycero-3-PE

Cat.No: T36453

1-Stearoyl-2-Adrenoyl-sn-glycero-3-PE

Cat.No: T38217

1-O-Octadecyl-2-O-methyl-sn-glycerol

Cat.No: T35489

1-Stearoyl-2-linoleoyl-sn-glycero-3-phosphocholine

Cat.No: T10030

Target: Others

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PC

Cat.No: T37485

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PC

Cat.No: T37486

1-Stearoyl-2-15(S)-HpETE-sn-glycero-3-PE

Cat.No: T37487

1-Stearoyl-2-15(S)-HETE-sn-glycero-3-PE

Cat.No: T37284

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphocholine

Cat.No: T10029

Target: Endogenous Metabolite

Cat.No: T72929

Synonym: 1-Stearoyl-2-docosahexaenoyl-sn-glycerol

Cat.No: T10832

Target: Others

1-Linoleoyl Lysophosphatidic Acid sodium

Cat.No: T83772

Synonym: 1-Linoleoyl-2-hydroxy-sn-glycero-3-PA,LPA(18:2),PA(18:2(9Z,12Z)/0:0),1-Octadecadienoyl-2-hydroxy-sn-glycero-3-phosphate,18:2 Lyso PA,1-Octadecadienoyl-2-hydroxy-sn-glycero-3-PA,PA(18:2/0:0),1-Linoleoyl-2-hydroxy-sn-glycero-3-phosphate,1-Linoleoyl LPA

Lysophosphatidylcholine C19:0

Cat.No: T81895

Synonym: 1-Nonadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Cat.No: T81216

Synonym: 1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphorylethanolamine

Cat.No: T69626

Cat.No: T71755

1-Palmitoyl-2-succinyl-sn-glycerophosphorylcholine

Cat.No: T83422

1-Palmitoyl-2-oleoyl-sn-glycerol

Cat.No: T74027

1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphoethanolamine

Cat.No: T67131

1-Stearoyl-2-arachidonoyl-sn-glycero-3-phosphoinositol

Cat.No: T75688

1-Stearoyl-2-myristoyl-sn-glycero-3-PC

Cat.No: T64546

1-Palmitoyl-2-[3-(diphenylhexatriene)propanoyl]-sn-phosphatidylcholine

Cat.No: T83423

1-Heptadecanoyl-2-hydroxy-sn-glycero-3-phosphocholine

Cat.No: T74179

1-O-Hexadecyl-2-O-docosahexaenoyl-sn-glycero-3-phosphorylcholine

Cat.No: T77230

1-Oleoyl-2-hydroxy-sn-glycero-3-phospho-L-serine sodium

Cat.No: T63847

Phosphatidylethanolamine from bovine

Cat.No: T38140

1,3-Dipalmitoyl-2-Octanoyl-rac-glycerol

Cat.No: T37706

Cat.No: T36079

1,2-Dierucoyl-sn-glycero-3-PC

Cat.No: T37623

1,3-Dipalmitoyl-2-Eicosapentaenoyl-rac-glycerol

Cat.No: T37125

1,2,3-Trilinoelaidoyl-rac-glycerol

Cat.No: T37383

Cat.No: T27811

1-Palmitoyl-2-Oleoyl-3-Arachidonoyl-rac-glycerol

Cat.No: T38216

Sacituzumab govitecan

Cat.No: T77824

Synonym: IMMU-132

1,2-Dilinoleoyl-sn-glycerol

Cat.No: T37122

1,3-Distearoyl-2-Oleoyl-rac-glycerol

Cat.No: T38358

1-Palmitoyl-2-Stearoyl-3-Oleoyl-rac-glycerol

Cat.No: T35443

Cat.No: T17730

Target: Others

Cat.No: T35441

4'-Methoxyflavonol

Cat.No: T19145

Target: Others

1-Oleoyl-2-Palmitoyl-rac-glycerol

Cat.No: T36005

1,2-Dioctanoyl PC

Cat.No: T37123

Cat. No.	Product Name	Target	Signaling Pathways
T19085	1-Palmitoyl-2-oleoyl-sn-glycero-3-PC POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine	Others	Others
	1-Palmitoyl-2-oleoyl-sn-glycero-3-PC (Palmitoyloleoylphosphatidylcholine) 是生物膜的主要成分，是一种磷脂。它用于脂质体的制备以及脂质双层的特性的研究。
T37280	PE(18:1(9Z)/0:0)	Endogenous Metabolite	Metabolism
	PE(18:1(9Z)/0:0) 是一种天然存在的溶血磷脂，是缩醛磷脂溶血磷脂酰乙醇胺的类似物。 PE(18:1(9Z)/0:0) 以浓度依赖性方式诱导 PC12 大鼠神经元细胞中细胞内钙的瞬时增加。 PE(18:1(9Z)/0:0) 增加 IL-4 和 IL-2 的产生，但不增加 IFN-γ 的产生。在小鼠血清中，PE(18:1(9Z)/0:0)（1 μg/动物）诱导 T 辅助细胞 2 反应。在寒冷暴露三天后，小鼠肩胛间棕色脂肪组织中的 PE(18:1(9Z)/0:0) 水平增加。
T5243	(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE	Others; Endogenous Metabolite	Metabolism; Others
	(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate (DMPE) 是内源性代谢产物的一种。
T74236	1-Oleoyl-2-palmitoyl-sn-glycero-3-PC
	1-Oleoyl-2-palmitoyl-sn-glycero-3-PC，由油酸衍生，用于脂质体合成。
T8011	1,2-dioleoyl-sn-glycero-3-phosphocholine 二油酰磷脂酰胆碱,DOPC	Others	Others
	1,2-dioleoyl-sn-glycero-3-phosphocholine (DOPC) 是磷脂的一种，在胶束，脂质体和其他类型的人工膜的生成中通常单独使用或与其他组分一起使用。
T38141	Glycerophospholipids, cephalins Phosphatidylethanolamines (egg)
	Glycerophospholipids, cephalins (Phosphatidylethanolamines (egg)) 是一种从鸡蛋中分离出来的磷脂酰乙醇胺的混合物，在 sn-1和 sn-2位置有各种脂肪酰基。Glycerophospholipids, cephalins 完全水解可得到1mol 的甘油、磷酸、乙醇胺和2mol 的脂肪酸。Phosphatidylethanolamines 在膜融合和细胞分裂过程中收缩环的拆卸中起作用，可调节膜的弯曲度。Phosphatidylethanolamines 能够在没有任何蛋白质或核酸的帮助下传播传染性朊病毒。Phosphatidylethanolamines 在细菌膜中的主要作用之一是分散由阴离子膜磷脂引起的负电荷。
T4439	sn-Glycero-3-phosphocholine Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC	Endogenous Metabolite; AChE	Metabolism; Neuroscience
	sn-Glycero-3-phosphocholine (Choline glycerophosphate) 是脑磷脂生物合成的前体，能够提高胆碱在神经组织中的生物利用度。它对认知功能有显著影响，同时具有良好的耐受性和安全性，因此能够用于阿尔茨海默病和痴呆症的研究。
T6S1559	Aurantio-obtusin	Others	Others
	Aurantio-obtusin 是从决明子中分离出的蒽醌类化合物，具有抗炎、抗凝血、抗氧化、抗高血压的活性。它能抑制 IgE 介导的肥大细胞和过敏模型中的过敏反应，具有研究过敏相关疾病的潜力。在大鼠中，它通过内皮细胞 PI3K/AKT/ eNOS 依赖信号通路放松全身动脉，是潜在的新型血管扩张剂。
T37884	1,3-Linolein-2-Olein
	1,3-Dilinoleoyl-2-oleoyl-rac-glycerol is a triacylglycerol that contains linoleic acid at the sn-1 and sn-3 positions and oleic acid at the sn-2 position. It has been found in grape seed, pumpkin seed, soybean, sunflower, and wheat germ oils, with the highest content in grape seed oil.
T36791	Lysophosphatidylcholine 18:2
	1-Linoleoyl-2-hydroxy-sn-glycero-3-PC (LGPC) is a lysophospholipid containing linoleic acid at thesn-1 position that has been found in mouse heart, lung, liver, spleen, kidney, plasma, and serum.1Serum levels of LGPC decrease with increasing insulin resistance and dysglycemia in humans.2 1.Okudaira, M., Inoue, A., Shuto, A., et al.Separation and quantification of 2-acyl-1-lysophospholipids and 1-acyl-2-lysophospholipids in biological samples by LC-MS/MSJ. Lipid Res.55(10)2178-2192(2014) 2.Gall, ...
T35577	Phosphatidylserines (bovine)
	Phosphatidylserine is a naturally occurring phospholipid that comprises 2-10% of total phospholipids in mammals and is enriched in the central nervous system, particularly the retina. It is anionic and found mainly on the inner leaflet of the cell membrane. It is biosynthesized from phosphatidylcholine or phosphatidylethanolamine by phosphatidyl synthase 1 (PSS1) or PSS2, respectively, in the endoplasmic reticulum and can be reversibly converted back by the same enzymes. It can also be irreversi...

天然产物

1-Palmitoyl-2-oleoyl-sn-glycero-3-PC

Cat.No: T19085

Synonym: POPC,2-油酰-1-棕榈锡甘油-3-磷酸胆碱,1-Palmitoyl-2-oleoyl-sn-glycero-3-phosphocholine,Palmitoyloleoylphosphatidylcholine

Target: Others

PE(18:1(9Z)/0:0)

Cat.No: T37280

Target: Endogenous Metabolite

(2R)-3-(((2-Aminoethoxy)(hydroxy)phosphoryl)oxy)propane-1,2-diyl ditetradecanoate

Cat.No: T5243

Synonym: DMPE,1,2-十四酰基磷脂酰乙醇胺,1,2-Dihexadecanoyl-sn-glycero-3-phosphoethanolamine,1,2-Dimyristoyl-sn-glycero-3-PE

Target: Others, Endogenous Metabolite

1-Oleoyl-2-palmitoyl-sn-glycero-3-PC

Cat.No: T74236

1,2-dioleoyl-sn-glycero-3-phosphocholine

Cat.No: T8011

Synonym: 二油酰磷脂酰胆碱,DOPC

Target: Others

Glycerophospholipids, cephalins

Cat.No: T38141

Synonym: Phosphatidylethanolamines (egg)

sn-Glycero-3-phosphocholine

Cat.No: T4439

Synonym: Choline Alfoscerate,甘磷酸胆碱,Glycerophosphocholine,Glycerophosphorylcholine,Alpha-GPC,Choline glycerophosphate,L-α-GPC

Target: Endogenous Metabolite, AChE

Aurantio-obtusin

Cat.No: T6S1559

Target: Others

1,3-Linolein-2-Olein

Cat.No: T37884

Lysophosphatidylcholine 18:2

Cat.No: T36791

Phosphatidylserines (bovine)

Cat.No: T35577

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