114
3
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61
Cat. No. | Product Name | ||
---|---|---|---|
L1610 | FDA 上市激酶抑制剂库 | 263 compounds | |
263种靶向激酶的上市药物集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; | |||
L1600 | 激酶抑制剂库 | 2720 compounds | |
2720 种激酶抑制剂/调节剂的独特集合,用于特定靶向激酶,可用于高通量筛选和高内涵筛选; |
Cat. No. | Product Name | Form | Specificity Of Inhibition |
---|---|---|---|
CL0092 |
GSK-3 inhibitor kit
GSK-3 inhibitor kit |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T35554 |
GSK-3β inhibitor 3
|
Apoptosis; GSK-3 | Apoptosis; PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 3 是一种糖原合成酶激酶 3β(GSK-3β)共价抑制剂 ( IC50 : 6.6 μM),具有强效性、选择性和不可逆性。GSK-3β inhibitor 3 可用于研究急性早幼粒细胞白血病。 | |||
T77342 |
GSK-3 inhibitor 3
|
GSK-3; Microtubule Associated | Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 inhibitor 3 是一种具有选择性、具有口服活性和脑渗透性的 GSK-3 抑制剂,对 GSK-3α 和 GSK-3β 具有抑制作用, IC50s 分别为 0.35 nM 和 0.25 nM。GSK-3 inhibitor 3 在三重转基因小鼠阿尔茨海默病模型中降低 Tau 蛋白 (tau protein) S396 磷酸化水平,IC50为 10 nM。GSK-3 inhibitor 3 可用于研究神经系统疾病。 | |||
T77341 |
GSK-3 inhibitor 4
|
GSK-3; CDK | Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 inhibitor 4 是一种具有口服活性和脑渗透性的 GSK-3,CDK2 和 CDK5 三重抑制剂,对 GSK-3β,GSK-3α,CDK2 和 CDK5 具有抑制作用,IC50 值分别为 0.56 nM ,0.45 nM ,0.47 μM,0.68 μM。GSK-3 inhibitor 4 可有效降低 Tau protein 水平。GSK-3 inhibitor 4 可用于研究阿尔茨海默症 。 | |||
T11468 |
GSK-3 inhibitor 1
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 inhibitor 1 is a GSK-3 inhibitor. | |||
T1917 |
GSK 3 Inhibitor IX
BIO,GSK 3 IX,6-BIO,6-Bromoindirubin-3'-oxime,MLS 2052,6-bromoindirubin-3-oxime |
Apoptosis; GSK-3; Tyrosine Kinases; CDK | Apoptosis; Cell Cycle/Checkpoint; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors |
GSK 3 Inhibitor IX (6-BIO) 是一种选择性可逆的,ATP 竞争性的 GSK-3α/β和 CDK1-cyclinB 复合体抑制剂,能够抑制 (GSK-3α/β)/CDK1/CDK5 的活性,IC50值分别为 5 nM/320 nM/83 nM。 | |||
T77554 |
GSK-3 Inhibitor 5
4-Cyanophenacyl bromide |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 Inhibitor 5 (4-Cyanophenacyl bromide) 是一种酮类衍生物,可作为医药和有机合成的中间体,且对糖原合成酶激酶3(GSK-3)有抑制作用。 | |||
T11467 |
GSK-3β inhibitor 1
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 1 是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂,其 IC50=4.9 nM,可用于糖尿病的研究。 | |||
T9178 |
(E/Z)-GSK-3β inhibitor 1
GSK-3β inhibitor 1 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
(E/Z)-GSK-3β inhibitor 1 是 (E)-GSK-3β inhibitor 1 和 (Z)-GSK-3β inhibitor 1 的消旋体。它是一种糖原合成酶激酶 3β (GSK-3β)的抑制剂,可其对 GSK-3β 的 IC50=4.9 nM,用于糖尿病的研究。 | |||
T9725 |
GSK-3β inhibitor 10
|
Others | Others |
GSK-3β inhibitor 10 具有美白、抗氧化和 PPAR 活性。 | |||
T6787 |
BIO-acetoxime
BIA,GSK-3 Inhibitor X |
Apoptosis; GSK-3; HSV | Apoptosis; Microbiology/Virology; PI3K/Akt/mTOR signaling; Stem Cells |
BIO-acetoxime (GSK-3 Inhibitor X) 是一种 GSK3α/β 抑制剂,IC50值均为 10 nM,具有抗惊厥和抗感染作用。 | |||
T78578 |
GSK-3 Inhibitor XIII
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3 Inhibitor XIII,一种ATP竞争性的 GSK-3抑制剂(Ki:24 nM),可用于研究糖尿病和肥胖。 | |||
T2073 |
GSK2636771
GSK 2636771,GSK-2636771 |
PI3K | PI3K/Akt/mTOR signaling |
GSK2636771 是选择性的、口服有效的PI3Kβ抑制剂,Ki=0.89 nM,IC50=5.2 nM,比p110α和p110γ的选择性高900倍,比p110δ同种型的选择性高10倍。 | |||
T2357 |
GSK1059615
GSK 1059615,GSK-1059615 |
Apoptosis; PI3K; mTOR | Apoptosis; PI3K/Akt/mTOR signaling |
GSK1059615 是一种 PI3Kα/β/δ/γ可逆的抑制剂,同时也抑制 mTOR,IC50值分别为 0.4 nM/0.6 nM/2 nM/5 nM 和 12 nM,已用于研究淋巴瘤、实体瘤、子宫内膜癌、实体瘤癌和转移性乳腺癌治疗的试验。 | |||
T22817 |
GSK 789472 hydrochloride
GSK 789472盐酸盐,GSK-789472 HCl,1-phenyl-3-(piperidin-2-ylmethyl)imidazolidin-2-one hydrochloride,4,5-Dihydro-1-phenyl-3-(2-piperidinyl)methylimidazol-2(1H)-one |
Dopamine Receptor | GPCR/G Protein; Neuroscience |
GSK 789472 hydrochloride 是多巴胺 D3 受体拮抗剂和 D2 部分激动剂。 | |||
T1861 |
Omipalisib
GSK458,GSK2126458 |
PI3K; mTOR; Autophagy | Autophagy; PI3K/Akt/mTOR signaling |
Omipalisib (GSK2126458) 是一种磷脂酰肌醇 3-激酶(PI3K) 的小分子吡啶磺酰胺抑制剂,具有抗肿瘤活性。它抑制 p110α/β/δ/γ,mTORC1/2 的活性,Ki 值分别为 0.019 nM/0.13 nM/0.024 nM/0.06 nM 和 0.18 nM/0.3 nM。 | |||
T6187 |
TDZD-8
GSK-3β Inhibitor I,NP 01139 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
TDZD-8 (NP 01139) 是抑制GSK-3β的抑制剂,其 IC50=2 μM。它对 Cdk-1/cyclin B,CK-II,PKA 和 PKC 的作用较弱,IC50值均 >100 μM。 | |||
T35555 |
GSK-3/CDK5/CDK2-IN-1
GSK-3/CDK5/CDK2-IN-1 |
||
GSK-3/CDK5/CDK2-IN-1 is an imidazole derivative compound that inhibits cdk5, cdk2, and GSK-3.it has demonstrated applications in cancer research and the study of neurodegenerative diseases [1]. | |||
T1881 |
AR-A014418
AR 0133418,GSK-3beta Inhibitor VIII,AR 014418,GSK 3β inhibitor VIII |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
AR-A014418 (GSK 3β inhibitor VIII) 是选择性的,ATP 竞争性的 GSK3β抑制剂 ,其 IC50=104 nM,Ki=38 nM。 | |||
T1965 |
Bikinin
Abrasin |
Others; GSK-3 | Others; PI3K/Akt/mTOR signaling; Stem Cells |
Bikinin (Abrasin) 是一种非甾体类的,ATP 竞争性的,植物性 GSK-3/Shaggy-like kinases 抑制剂,可激活 BR 信号通路。 | |||
T24111 |
GSK3i XIII
GSK3 inhibitor XIII,GSK3iXIII,GSK3i-XIII |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK3i XIII (GSK3 inhibitor XIII) 是ATP 竞争性GSK-3抑制剂(Ki: 24 nM)。 | |||
T14066 |
9-ING-41
|
Apoptosis; GSK-3; Autophagy | Apoptosis; Autophagy; PI3K/Akt/mTOR signaling; Stem Cells |
9-ING-41 是基于马来酰亚胺的 ATP 竞争性和选择性的糖原合酶激酶-3β 抑制剂,IC50为 0.71 μM。它显著导致癌细胞的细胞周期停滞,自噬和凋亡,具有增强化疗药物抗肿瘤作用的潜力,有抗癌活性。 | |||
T1957 |
AZD2858
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
AZD2858 是具有口服活性的GSK-3抑制剂,可以抑制 GSK-3α (IC50:0.9 nM) 和 GSK-3β (IC50:5 nM) 的活性,可用于骨折愈合的研究。 | |||
T5956 |
VP3.15 dihydrobromide
|
GSK-3; PDE | Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
VP3.15 dihydrobromide 是一种口服具有活力的、高效的、CNS 可渗透的PDE7-GSK3双重抑制剂,对 PDE7 和 GSK3 作用的IC50值分别为 1.59 μM 和 0.88 μM。它具有神经保护和神经修复作用,可用于研究多发性硬化症 (MS) 潜在的抗炎和促髓鞘再生联合。 | |||
T22820 |
GSK J5 HCl (1394854-51-3 free base)
GSK J5 HCl |
Others | Others |
GSK J5 HCl is the hydrochloride form of GSK J5. GSK J5 is an inactive isomer of GSK J4 and a cell-permeable ester derivative of inactive control GSK J2. | |||
T10202 |
A 1070722
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
A 1070722 是高效的糖原合成酶激酶 3 (GSK-3)选择性抑制剂,与 GSK-3α 和 GSK-3β 结合的Ki 为 0.6 nM。A 1070722 可以穿透血脑屏障并在脑区积聚,具有作为PET 放射性跟踪剂定量测定脑部 GSK-3的潜力。 | |||
T19840 |
GSK-F1
PI4KA inhibitor-F1 |
PI4K | PI3K/Akt/mTOR signaling |
GSK-F1 (PI4KA inhibitor-F1) 是一种新型强效 PI4KA 抑制剂。 | |||
T9987 |
GSK3-IN-1
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK3-IN-1是一种 GSK3B-糖原合酶激酶3β抑制剂。 | |||
T1755 |
LY2090314
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
LY2090314 是GSK-3抑制剂,抑制 GSK-3α (IC50:1.5 nM) 和 GSK-3β (IC50:0.9 nM)。 | |||
T1741 |
AZD1080
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
AZD1080 是一种选择性GSK3抑制剂。它抑制重组人GSK3α和GSK3β,pKi(IC50) 分别为 8.2 (6.9 nM) 和 7.5 (31 nM)。 | |||
T2166 |
TWS119
|
GSK-3; Autophagy | Autophagy; PI3K/Akt/mTOR signaling; Stem Cells |
TWS119 是一种GSK-3β特异性抑制剂,IC50值为 30 nM,它可激活 wnt/β-catenin 信号通路,能够诱导神经元分化。 | |||
T3077 |
SB 216763
SB216763 |
GSK-3; Autophagy | Autophagy; PI3K/Akt/mTOR signaling; Stem Cells |
SB 216763 (SB216763) 是一种选择性和ATP 竞争性的GSK-3α/β抑制剂,IC50为34.3 nM。 | |||
T2261 |
IM-12
IM 12 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
IM-12 是一种 GSK-3β的抑制剂,其 IC50=53 nM,可提高 Wnt 信号传导。 | |||
T67856 |
GSK-3β inhibitor 14
1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)- |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 14 (1,5-Benzothiazepin-4(5H)-one, 2,3-dihydro-2-methyl-5-(phenylmethyl)-) 是一种较弱的 GSK-3β 抑制剂,IC50﹥ 100μM。 | |||
T5200 |
Indirubin-3'-monoxime
靛玉红-3' -单肟,Indirubin-3'-oxime |
GSK-3; Lipoxygenase; CDK | Cell Cycle/Checkpoint; Metabolism; PI3K/Akt/mTOR signaling; Stem Cells |
Indirubin-3'-monoxime (Indirubin-3'-oxime) 是一种有效的 GSK3β 抑制剂,IC50值为 22 nM。它对 CDK5/p25、CDK1/cyclin B 和CDk2/cyclin E 也有作用,IC50值分别为 100、180 和 250 nM。 | |||
T21966 |
MeBIO
|
GSK-3; Aryl Hydrocarbon Receptor; CDK | Cell Cycle/Checkpoint; Immunology/Inflammation; PI3K/Akt/mTOR signaling; Stem Cells |
MeBIO 是一种芳烃受体激动剂,对 GSK-3 和 CDK1/CyclinB 的 IC50 分别为 44 和 55 μM。 MeBIO 不影响 GSK-3β。 | |||
T12664 |
(Rac)-BRD0705
|
Others | Others |
(Rac)-BRD0705 是 BRD0705 的活性较低的外消旋体。 BRD0705 是一种有效的特异性 GSK3α 抑制剂。 | |||
T7361 |
Verucerfont
NBI77860,3-(4-甲氧基-2-甲基苯基)-2,5-二甲基-N-[(1S)-1-(3-甲基-1,2,4-恶二唑-5-基)丙基]吡唑并[1,5-A]嘧啶-7-胺,GSK561679 |
CRFR | GPCR/G Protein |
Verucerfont (NBI77860) 是促肾上腺皮质激素释放因子受体 1 (CRF1) 拮抗剂,作用于 CRF1(IC50:6.1 nM),CRF2 (IC50>1000 nM)和 CRF-BP (IC50>1000 nM)。 | |||
T11471 |
GSK-3β inhibitor 2
GSK-3β 抑制剂 2,5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy- |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 2 (5-Thiazolecarboxamide,2-[2-[(cyclopropylcarbonyl)amino]-4-pyridinyl]-4-methoxy-) 是一种特异性的 GSK-3β 抑制剂 (IC50 = 1.1 nM)。 GSK-3β inhibitor 2 可用于阿尔茨海默病的研究。 | |||
T61809 |
GSK-3β inhibitor 11
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 11(compound 21)是一种强效的糖原合成酶激酶-3β(GSK-3β)抑制剂,其抑制浓度(IC50)为10.02 μM。该化合物在神经退行性疾病研究领域展示了潜在的应用价值[1]。 | |||
T21956 |
GSK3β inhibitor II
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK3β inhibitor II 是 GSK3β 的抑制剂。GSK3β inhibitor II 可用于研究阿尔茨海默病 (AD)。 | |||
T60472 |
GSK-3β inhibitor 12
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
GSK-3β inhibitor 12 是一种选择性 GSK-3β 的抑制剂。GSK-3β inhibitor 12 抑制 49.11% 25 μM 的 GSK-3β 的活性和37.11% 50 μM 的 GSK-3β 的活性。GSK-3β inhibitor 12 可用于研究有脂多糖诱导的帕金森。 | |||
T9138 |
Indirubin-3′-oxime
Indirubin-3'-monoxime |
GSK-3; CDK; JNK | Cell Cycle/Checkpoint; MAPK; PI3K/Akt/mTOR signaling; Stem Cells |
Indirubin-3′-oxime 是一种有效的细胞周期蛋白依赖性蛋白激酶抑制剂,是 indirubin 的合成衍生物。它可通过激活软骨细胞中的 Wnt/β-catenin 信号来促进身高增长,可能在阿尔茨海默病的神经元凋亡中发挥作用。 | |||
T3074 |
CHIR 98024
CHIR98014 |
GSK-3; S6 Kinase | MAPK; PI3K/Akt/mTOR signaling; Stem Cells |
CHIR 98024是一种有效的 GSK-3α/β 抑制剂,在无细胞试验中 IC50 为 0.65 nM/0.58 nM,能够区分 GSK-3 与其接近的同源物 Cdc2 和 ERK2。 | |||
T3684 |
CP21R7
CP21 |
GSK-3; PKC | Chromatin/Epigenetic; Cytoskeletal Signaling; PI3K/Akt/mTOR signaling; Stem Cells |
CP21R7 (CP21) 是一种 GSK-3β抑制剂,其 IC50=1.8 nM。它也是一种 PKCα抑制剂,其 IC50=1900 nM。 | |||
T10606 |
BRD0705
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
BRD0705 是一种具有旁系选择性的、口服具有活性的GSK3α抑制剂,其 IC50=66 nM,Kd=4.8 μM。 它与 GSK3β (其 IC50=515 nM) 相比,对GSK3α的选择性更高 (8 倍)。它可用于研究急性髓细胞性白血病。 | |||
T2608 |
CHIR-98014
CHIR 98014,CT98014,CHIR98014 |
FGFR; GSK-3; Src; S6 Kinase | Angiogenesis; MAPK; PI3K/Akt/mTOR signaling; Stem Cells; Tyrosine Kinase/Adaptors |
CHIR-98014 (CT98014) 是有效的,细胞通透的GSK-3抑制剂,可抑制 GSK-3α (IC50:0.65 nM) 和 GSK-3β (IC50:0.58 nM) 的活性,对 cdc2 和 erk2 的作用较弱。 | |||
T3067 |
Tideglusib
NP-12,NP031112 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
Tideglusib (NP031112) 是不可逆的 GSK-3抑制剂,能够抑制 GSK-3βWT (IC50:5 nM) 和 GSK-3βC199A (IC50:60 nM)。 | |||
T15438 |
GSK3186899
3,3,3-trifluoro-N-[4-[[3-[(2R)-2-methylmorpholin-4-yl]-1H-pyrazolo[3,4-d]pyrimidin-6-yl]amino]cyclohexyl]propane-1-sulfonamide,DDD-853651 |
Parasite | Microbiology/Virology |
GSK3186899 是 Cdc2 相关激酶 12 的抑制剂,对 L. donovani 的 EC50 为 1.4 μM。 | |||
T10608 |
BRD5648
(R)-BRD0705 |
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
BRD5648 ((R)-BRD0705) 是 BRD0705 的 阴性对照,BRD0705 是旁系选择性和口服有效的 GSK3α 抑制剂,Kd 为 4.8 μM,IC50为 66 nM。与 GSK3β (IC50为 515 nM) 相比,BRD0705 对 GSK3α 的选择性更高 (8 倍)。BRD0705 可用于急性髓细胞性白血病。 | |||
T9611 |
PF-04802367
|
GSK-3 | PI3K/Akt/mTOR signaling; Stem Cells |
PF-04802367是 GSK-3高选择性抑制剂,对 GSK-3β酶的 IC50为 2.1 nM。它抑制两种 GSK-3 亚型(GSK-3α和GSK-3β)效果差不多,IC50值分别为 10.0 和 9.0 nM。它具有理想的中枢神经系统特性和效力。 |
Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T6S0653 |
Linarin
Buddleoflavonoloside,Buddleoside,Acacetin-7-O-rutinoside,Acaciin,Linarine,蒙花苷 |
TNF; AChE | Apoptosis; Neuroscience |
Linarin (Acacetin-7-O-rutinoside) 是一种选择性的乙酰胆碱酯酶 (AChE) 抑制剂,从薄荷花提取物中分离得到。 | |||
TN1702 |
Glycycoumarin
甘草香豆素 |
P450; JNK; AMPK; Autophagy | Autophagy; Chromatin/Epigenetic; MAPK; Metabolism; PI3K/Akt/mTOR signaling |
Glycycoumarin 是甘草中的一种香豆素,能直接靶向 T-LAK 细胞源蛋白激酶发挥抗肝癌活性 。它通过激活自噬,抑制内质网应激介导的 JNK 和 GSK-3 介导的线粒体途径,来抑制肝细胞脂性凋亡。它是一种雌激素激动剂,对 CYP1A2 和 CYP2B6 有中度抑制作用。 | |||
T27977 |
Manzamine A
Keramamine A |
||
Manzamine A is a GSK-3 inhibitor and vacuolar ATPase uncoupler found in marine sponges. It inhibits autophagy and tumor growth in cancer models, suppresses foam cell formation in macrophages, prevents growth of gram negative and gram positive bacteria, an |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPY-04439 |
GSK3B Protein, Mouse, Recombinant (His)
GSK-3,7330414F15Rik,C861... |
Mouse | Baculovirus Insect Cells |
GSK3B Protein, Mouse, Recombinant (His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49 kDa and the accession number is Q9WV60. | |||
TMPY-06986 |
FGF-8b Protein, Human, Recombinant
NEWENTRY,fibroblast growth factor 8 (androgen-induced),FGF-8... |
Human | E. coli |
In mammalian embryos, transient Fgf8 expression defines the developing isthmic region, lying between the midbrain and the first rhombomere, but there has been uncertainty about the existence of a distinct isthmic segment in postnatal mammals. Retinoic acid (RA) directly represses Fgf8 through a RARE-mediated mechanism that promotes repressive chromatin, thus providing valuable insight into the mechanism of RA-FGF antagonism during progenitor cell differentiation. Fgf8 encodes a key signaling fac... | |||
TMPY-00132 |
Mesothelin Protein, Human, Recombinant
MPF,SMRP,Mesothelin |
Human | HEK293 Cells |
Mesothelin Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 32.4 kDa and the accession number is Q13421-3. | |||
TMPY-04935 |
CD47 Protein, Human, Recombinant (aa 1-139, His)
MER6,CD47 molecule,IAP,OA3 |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (aa 1-139, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 15.2 kDa and the accession number is Q08722-3. | |||
TMPY-03763 |
Neuropilin-2 Protein, Human, Recombinant (hFc)
Neuropilin-2,NPN2,neuropilin 2,PRO2714,VEGF165R2,NP2 |
Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 120.7 kDa and the accession number is O60462-3. | |||
TMPY-05191 |
CD47 Protein, Human, Recombinant, Biotinylated
CD47 molecule,MER6,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant, Biotinylated is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-04683 |
CD47 Protein, Human, Recombinant
MER6,CD47 molecule,OA3,IAP |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 14.5 kDa and the accession number is Q08722-3. | |||
TMPY-00072 |
GITR/TNFRSF18 Protein, Human, Recombinant (His)
AITR,GITR-D,tumor necrosis factor receptor superfamily, memb... |
Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 16 kDa and the accession number is Q9Y5U5-3. | |||
TMPY-05748 |
CD45 Protein, Human, Recombinant (aa 26-577, His)
L-CA,T200,LCA,B220,protein tyrosine phosphatase, receptor ty... |
Human | HEK293 Cells |
CD45 Protein, Human, Recombinant (aa 26-577, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 62.2 kDa and the accession number is P08575-3. | |||
TMPY-04142 |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc)
OPTB7,OFE,OSTS,LOH18CR1,FEO,TRANCER,tumor necrosis factor re... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 46.8 kDa and the accession number is Q9Y6Q6-3. | |||
TMPJ-01099 |
IL-15RA Protein, Human, Recombinant (hFc, Human Cells)
interleukin-15 receptor subunit α,IL15RA,interleukin-15 rece... |
Human | HEK293 Cells |
Interleukin 15 Receptor alpha (IL-15Rα) is a transmembrane glycoprotein that plays a pleiotropic role in immune development and function, including the positive maintenance of lymphocyte homeostasis. IL-15Rα chain can bind soluble IL-15 and “transpresent” cytokine to the cells, allowing them to respond to IL-15. Soluble IL-15Rα can function as a specific high-affinity IL-15 antagonist. The soluble IL-15/IL-15Rα complexes exhibit a strong agonistic activity which is mediated through membrane-boun... | |||
TMPY-01180 |
CD86 Protein, Human, Recombinant (His)
CD86 antigen,B70,B7.2,B7-2,CD28LG2,LAB72 |
Human | HEK293 Cells |
CD86 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 26.6 kDa and the accession number is P42081-3. | |||
TMPY-01020 |
Periostin/OSF-2 Protein, Human, Recombinant (His)
PN,OSF-2,OSF2,periostin,periostin, osteoblast specific facto... |
Human | HEK293 Cells |
Periostin/OSF-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 86.4 kDa and the accession number is Q15063-3. | |||
TMPY-01897 |
PRSS3 Protein, Human, Recombinant (His)
PRSS4,TRY4,TRY3,RP11-176F3.3,T9,M... |
Human | HEK293 Cells |
Trypsin-3, also known as Trypsin III, brain trypsinogen, Serine protease 3 and PRSS3, is a secreted protein that belongs to the peptidase S1 family. Trypsin-3 / PRSS3 is expressed is in pancreas and brain. It contains one peptidase S1 domain. Trypsin-3 / PRSS3 can degrade intrapancreatic trypsin inhibitors that protect against CP. Genetic variants that cause higher mesotrypsin activity might increase the risk for chronic pancreatitis (CP). A sustained imbalance of pancreatic proteases and their ... | |||
TMPY-00892 |
Neuropilin-2 Protein, Human, Recombinant (His)
NP2,PRO2714,VEGF165R2,neuropilin 2,NPN2,Neuropilin-2 |
Human | HEK293 Cells |
Neuropilin-2 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 95 kDa and the accession number is O60462-3. | |||
TMPY-04298 |
CDCP1 Protein, Human, Recombinant (His)
TRASK,CD318,CUB domain containing protein 1,SIMA1 |
Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 36.4 kDa and the accession number is Q9H5V8-3. | |||
TMPY-00357 |
HNT/NTM Protein, Human, Recombinant (His)
HNT,NTRI,IGLON2,neurotrimin |
Human | HEK293 Cells |
HNT/NTM Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 32.3 kDa and the accession number is Q9P121-3. | |||
TMPY-00480 |
NCAM1 Protein, Human, Recombinant (His)
neural cell adhesion molecule 1,CD56,MSK39,NCAM |
Human | HEK293 Cells |
NCAM1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 66.1 kDa and the accession number is P13591-3. | |||
TMPY-01165 |
FZD1/Frizzled 1 Protein, Mouse, Recombinant (His)
Fzd1,AW227548,frizzled class receptor 1,FZ-1,Fz1 |
Mouse | HEK293 Cells |
Frizzled-1, also known as FZD1, belongs to theG-protein coupled receptor Fz/Smo family. FZD1 contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, 7 transmembrane domains, and a C-terminal PDZ domain-binding motif. FZD1 is expressed in adult heart, placenta, lung, kidney, pancreas, prostate, and ovary and in fetal lung and kidney. Frizzled is a family of G protein-coupled receptor proteins that serve as receptors in the Wnt signaling pathway and other signalin... | |||
TMPK-00447 |
CD45 Protein, Human, Recombinant (aa 26-577, hFc)
CD45,CD45R,LCA,PTPRC,L-CA,T200,B220,GP180,LY5,EC 3.... |
Human | HEK293 Cells |
PTPRC (also known as CD45),T cells require the protein tyrosine phosphatase CD45 to detect and respond to antigen because it activates the Src family kinase Lck, which phosphorylates the T cell antigen receptor (TCR) complex. CD45 ativates Lck by opposing the negative regulatory kinase Csk. Paradoxically, CD45 has also been implicated in suppressing TCR signaling by dephosphorylating the same signaling motifs within the TCR complex upon which Lck acts. CD45 Protein, Human, Recombinant (aa 26-577... | |||
TMPY-03621 |
EphB2 Protein, Mouse, Recombinant (hFc)
Tyro5,Erk,Qek5,ETECK,Hek5,Drt,EPH receptor B2,Nuk,Prkm5,Sek<... |
Mouse | HEK293 Cells |
EphB2 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 84.6 kDa and the accession number is P54763-3. | |||
TMPJ-01288 |
KLF6 Protein, Human, Recombinant
CPBP,GC-Rich Sites-Binding Factor GBF,Suppressor of Tumorige... |
Human | E. coli |
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localizes in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will resul... | |||
TMPY-04386 |
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST)
PCBC,CAPB,Hek5,EK5,EPHT3,EPH receptor B2,Tyro5,DRT,... |
Human | Baculovirus Insect Cells |
EphB2 Protein, Human, Recombinant (aa 570-987, His & GST) is expressed in Baculovirus insect cells with His and GST tag. The predicted molecular weight is 75.2 kDa and the accession number is P29323-3. | |||
TMPY-01268 |
SMYD3 Protein, Human, Recombinant (GST)
SET and MYND domain containing 3,ZMYND1,KMT3 |
Human | Baculovirus Insect Cells |
SET and MYND domain-containing protein 3, also known as Zinc finger MYND domain-containing protein 1, SMYD3, and ZMYND, is a member of the histone-lysine methyltransferase family. SMYD3 contains one MYND-type zinc finger and one SET domain. SMYD3 is a histone H3 lysine-4-specific methyltransferase. It is expressed in skeletal muscles and testis. It is overexpressed in a majority of colorectal carcinoma (CRC) and hepatocellular carcinoma (HCC). SMYD3 plays an important role in transcriptional reg... | |||
TMPY-03149 |
CDCP1 Protein, Human, Recombinant (mFc)
TRASK,SIMA135,CD318,CUB domain containing ... |
Human | HEK293 Cells |
CDCP1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 61.4 kDa and the accession number is Q9H5V8-3. | |||
TMPK-00401 |
FGFR2 alpha (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
ECT1,K-SAM,CD332,CEK3,FGFR2 α,CFD... |
Human | HEK293 Cells |
Four distinct genes encoding closely related FGF receptors, FGF R1 - 4, are known. All four genes for FGF Rs encode proteins with an N-terminal signal peptide, three immunoglobulin (Ig)-like domains, an acid-box region containing a run of acidic residues between the IgI and IgII domains, a transmembrane domain and the split tyrosine-kinase domain. Multiple forms of FGF R1 - 3 are generated by alternative splicing of the mRNAs. | |||
TMPK-00398 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi)
Fibroblast growth factor receptor 2,CD332,... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi) is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPJ-00391 |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc)
FGF R2b,KGFR,BFR-1,FGFR2 β,FGFR2b,FGFR2,FGFR2 beta,CD3 |
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (aa 22-378, hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 85-120 KDa and the accession number is P21802-3. | |||
TMPY-05514 |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc)
OFE,RANK,OPTB7,FEO,tumor necrosis factor receptor superfamil... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 46.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPY-00276 |
PLGF/PGF Protein, Human, Recombinant (mFc)
placental growth factor,D12S1900,PLGF,SHGC-10760,PGFL,PlGF-2 |
Human | HEK293 Cells |
PLGF/PGF Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 43.7 kDa and the accession number is P49763-3. | |||
TMPY-03960 |
COL9A1 Protein, Human, Recombinant (His)
EDM6,collagen, type IX, α1,STL4,collagen, type IX, alpha 1,M... |
Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 34.2 kDa and the accession number is P20849-3. | |||
TMPY-04015 |
COL9A1 Protein, Human, Recombinant (mFc)
DJ149L1.1.2,STL4,collagen, type IX, alpha 1,MED,EDM6,collage... |
Human | HEK293 Cells |
COL9A1 Protein, Human, Recombinant (mFc) is expressed in HEK293 mammalian cells with mFc tag. The predicted molecular weight is 59.2 kDa and the accession number is P20849-3. | |||
TMPY-06411 |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated
CD357,GITR-D,tumor necrosis factor receptor superfa... |
Human | HEK293 Cells |
GITR/TNFRSF18 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 17.79 kDa and the accession number is Q9Y5U5-3. | |||
TMPK-00400 |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated
Fibroblast growth factor receptor 2,KGFR,FGFR-2,KSAM,CD3... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted molecular weight is 28.3 kDa and the accession number is P21802-3. | |||
TMPK-00399 |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated
Keratinocyte growth factor receptor,K-sam,BEK,FGFR2 β (IIIb)... |
Human | HEK293 Cells |
FGFR2 beta (IIIb) Domain Protein, Human, Recombinant (Avi), Biotinylated is expressed in HEK293 mammalian cells with C-Avi tag. The predicted molecular weight is 15.49 kDa and the accession number is P21802-3. | |||
TMPY-03705 |
VEGF164 Protein, Canine, Recombinant
血管内皮生长因子,vascular endothelial growth factor A |
Canine | HEK293 Cells |
VEGF164 Protein, Canine, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 17 kDa and the accession number is Q9MYV3-3. | |||
TMPY-04157 |
RANK/TNFRSF11A Protein, Human, Recombinant (His)
ODFR,OFE,CD265,PDB2,RANK,tumor necrosis factor receptor supe... |
Human | HEK293 Cells |
RANK/TNFRSF11A Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 21.5 kDa and the accession number is Q9Y6Q6-3. | |||
TMPK-00729 |
Siglec-6 Protein, Human, Recombinant (His & Avi)
SIGLEC6,OBBP1,CD327,CD33L1,CD... |
Human | HEK293 Cells |
Siglecs (Sialic acid binding Ig-like Lectins) are I-type (Ig-type) lectins that belong to the Ig superfamily. They are characterized by an N-terminal Ig-like V-type domain which mediates sialic acid binding, followed by varying numbers of Ig-like C2-type domains.Putative adhesion molecule that mediates sialic-acid dependent binding to cells. Binds to alpha-2,6-linked sialic acid. The sialic acid recognition site may be masked by cis interactions with sialic acids on the same cell surface. | |||
TMPY-05590 |
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated
NCAM,MSK39,CD56,neural cell adhesion molecule 1 |
Human | HEK293 Cells |
NCAM1 Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with His and Avi tag. The predicted molecular weight is 67.9 kDa and the accession number is P13591-3. | |||
TMPJ-00390 |
FGFR2IIIb Protein, Human, Recombinant (hFc)
FGFR2,FGFR2 beta,FGFR2 β,FGFR2IIIb,KGFR,FGF R2b,BFR-1,FGFR2b... |
Human | HEK293 Cells |
FGFR2IIIb Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with C-Fc tag. The predicted molecular weight is 70-90 KDa and the accession number is P21802-3. | |||
TMPY-01692 |
NETO1 Protein, Human, Recombinant (His)
neuropilin (NRP) and tolloid (TLL)-like 1,BCTL1,BTCL1 |
Human | HEK293 Cells |
Neuropilin tolloid-like 1 (NETO1), a complement C1r/C1s, Uegf, Bmp1 (CUB) domain-containing transmembrane protein, is a novel component of the NMDAR complex critical for maintaining the abundance of NR2A-containing NMDARs in the postsynaptic density. The N-methyl-D-aspartate receptor (NMDAR), a major excitatory ligand-gated ion channel in the central nervous system (CNS), is a principal mediator of synaptic plasticity. Both NETO1 and NETO2 share an identical and unique domain structure thus repr... | |||
TMPY-00715 |
CD84 Protein, Human, Recombinant (His)
LY9B,mCD84,CD84 molecule,hCD84,SLAMF5 |
Human | HEK293 Cells |
CD84 Protein, Human, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 24 kDa and the accession number is Q9UIB8-3. | |||
TMPY-04216 |
EphB2 Protein, Mouse, Recombinant (His)
Drt,Nuk,Qek5,Tyro5,Prkm5,Sek3,ETECK,Cek5,Hek5,EPH r... |
Mouse | HEK293 Cells |
EphB2 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 59.3 kDa and the accession number is P54763-3. | |||
TMPJ-00465 |
PTP1C Protein, Human, Recombinant (His)
HCP,Hematopoietic Cell Protein-Tyrosine Phosphatase,SH-PTP1,... |
Human | E. coli |
Protein-Tyrosine Phosphatase 1C (PTP1C) belongs to the protein-tyrosine phosphatase family.which is known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. PTP1C is highly expressed in leukocyte cell type. It contains two SH2 domains and one tyrosine-protein phosphatase domain. The SH2 regions may interact with other cellular components to modulate its own phosphatase activity against inter... | |||
TMPY-03883 |
CD47 Protein, Human, Recombinant (hFc)
OA3,CD47 molecule,IAP,MER6 |
Human | HEK293 Cells |
CD47 Protein, Human, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 40.7 kDa and the accession number is Q08722-3. | |||
TMPY-01656 |
VEGF183 Protein, Human, Recombinant
血管内皮生长因子,VEGF165,VPF,VEGF,vascular endothelial growth factor... |
Human | Baculovirus Insect Cells |
VEGF183 Protein, Human, Recombinant is expressed in Baculovirus insect cells. The predicted molecular weight is 21 kDa and the accession number is P15692-3. | |||
TMPY-03969 |
SUSD4 Protein, Human, Recombinant (mFc)
sushi domain containing 4,PRO222 |
Human | HEK293 Cells |
SUSD4, also known as sushi domain-containing protein 4, is a hypothetical cell surface protein whose tissue distribution and function are completely unknown. SUSD4 is detectable in murine brains, eyes, spinal cords, and testis but not other tissues. In brains, SUSD4 is highly expressed in the white matter on oligodendrocytes/axons, and in eyes, it is exclusively expressed on the photoreceptor outer segments. In in vitro complement assays, SUSD4 augments the alternative but not the classical path... | |||
TMPY-02573 |
IL-17RC Protein, Human, Recombinant (aa 1-454, His)
IL17RL,interleukin 17 receptor C,IL17-RL,UNQ6118/PRO20040/PR... |
Human | Baculovirus Insect Cells |
IL-17RC Protein, Human, Recombinant (aa 1-454, His) is expressed in Baculovirus insect cells with His tag. The predicted molecular weight is 49.6 kDa and the accession number is Q8NAC3-3. | |||
TMPY-04273 |
FGFR2 Protein, Human, Recombinant (aa 1-378, His)
TK25,ECT1,JWS,fibroblast growth factor receptor 2,CD3 |
Human | HEK293 Cells |
FGFR2 Protein, Human, Recombinant (aa 1-378, His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 41.1 kDa and the accession number is P21802-3. | |||
TMPY-03435 |
NCKIPSD Protein, Human, Recombinant (GST)
NCK interacting protein with SH3 domain,WASLBP,SPIN... |
Human | E. coli |
NCKIPSD is localized exclusively in the cell nucleus. It plays a role in signal transduction and may function in the maintenance of sarcomeres and the assembly of myofibrils into sarcomeres. NCKIPSD also plays an important role in stress fiber formation. NCKIPSD gene is involved in therapy-related leukemia by a chromosomal translocation t(3;11)(p21;q23) that involves this gene and the myeloid/lymphoid leukemia gene. Alternative splicing occurs in this locus and two transcript variants encoding d... | |||
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