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  • ADC Cytotoxin
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TargetMol产品目录中 "

Duocarmycin

"的结果
  • 抑制剂&激动剂
    27
    TargetMol | Inhibitors_Agonists
  • PROTAC
    4
    TargetMol | PROTAC
  • Duocarmycin DM free base
    Duocarmycin
    T111191116745-06-2
    Duocarmycin is a DNA minor groove binding alkylating agent and explored as drug–antibody conjugates (ADCs) . Duocarmycin is based on its characteristic curved indole structure and a spirocyclopropylcyclohexadienone electrophile to act anticancer activity.
    • 待询
    3-6月
    规格
    数量
  • duocarmycin tm
    T11120157922-77-5
    Duocarmycin TM 是一种有抗肿瘤活性的抗生素,也是一种 DNA 烷化剂。
    • ¥ 1320
    现货
    规格
    数量
    TargetMol | Inhibitor Hot
  • Duocarmycin analog-2
    T635231164275-01-7
    Duocarmycin analog-2 是有效的 DNA 烷基化剂,表现出抗肿瘤作用,能够用于免疫偶联物的合成。
    • ¥ 14900
    8-10周
    规格
    数量
  • Mal-PEG4-VC-PAB-DMEA-duocarmycin SA
    T205781
    Mal-PEG4-VC-PAB-DMEA-duocarmycin SA 是一种硫醇反应型 Drug-linker,duocarmycin SA 是一种非常有效的、具有口服活性的细胞毒性剂,可用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • Duocarmycin A
    T15180118292-34-5
    Duocarmycin A, an antitumor antibiotic, is a DNA alkylator and efficiently alkylates adenine N3 at the 3′ end of AT-rich sequences in the DNA. Duocarmycin A, as a chemotherapeutic agent, results in HLC-2 cells typically apoptotic changes.
    • 待询
    3-6月
    规格
    数量
  • Seco-Duocarmycin TM
    T12875236102-87-7
    Seco-Duocarmycin TM is an agent of DNA alkylator belonging to Duocarmycins family that inhibits DNA synthesis. It used as the cytotoxic component in antibody-drug conjugates (ADC).
    • ¥ 11700
    6-8周
    规格
    数量
  • Duocarmycin Analog
    T19300372954-15-9
    Duocarmycin Analog is used as an DNA alkylator and ADC cytotoxin. Duocarmycin Analog is an analog of Duocarmycin.
    • ¥ 15000
    8-10周
    规格
    数量
  • Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA
    T182932259318-49-3
    Mal-PEG4-VC-PAB-DMEA-Seco-Duocarmycin SA is an antibody-drug conjugate linker that incorporates the antitumor antibiotic Duocarmycin SA, connected through the Mal-PEG4-VC-PAB-DMEA-Seco linker, for targeted cancer therapy.
    • 待询
    规格
    数量
  • Fmoc-Val-Cit-PAB-Duocarmycin TM
    T17982
    Fmoc-Val-Cit-PAB-Duocarmycin TM is a drug-linker conjugate designed for antibody-drug conjugation (ADC), utilizing the antitumor antibiotic Duocarmycin TM. It is connected through the linker Fmoc-Val-Cit-PAB.
    • 待询
    规格
    数量
  • DBCO-PEG4-VC-PAB-DMEA-Duocarmycin SA
    T205798
    DBCO-PEG4-VC-PAB-DMEA-Duocarmycin SA 是一种是一种点击反应型 Drug-linker,含有 DBCO 基团,可以和含有 Azide 基团的分子发生环张力 (strain) 促进的炔-叠氮环加成反应 (SPAAC)。duocarmycin SA 是一种非常有效的、具有口服活性的细胞毒性剂,DBCO-PEG4-VC-PAB-DMEA-Duocarmycin SA可用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • Seco-Duocarmycin SA
    T12813L144667-38-9
    Seco-Duocarmycin SA is a highly potent DNA alkylator used as an ADC cytotoxin.
    • ¥ 19400
    3-6月
    规格
    数量
  • MA-PEG4-VC-PAB-DMEA-duocarmycin TM
    T205786
    MA-PEG4-VC-PAB-DMEA-duocarmycin TM 是一种硫醇反应型 Drug-linker,Duocarmycin TM 是一种有效的有抗肿瘤活性的抗生素,常用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • Duocarmycin SA
    T11118130288-24-3
    Duocarmycin SA is an extremely potent cytotoxic agent and antitumor antibiotic that induces sequence-selective alkylation of duplex DNA, with an IC50 of 10 pM. It demonstrates synergistic cytotoxicity against glioblastoma multiforme (GBM) cells when combined with proton radiation in vitro.
    • 待询
    3-6月
    规格
    数量
  • Duocarmycin DM
    T73948
    Duocarmycin DM,一种DNA小沟烷基化剂(DNA minor-groove alkylator),作为抗体活性分子结合物(ADCs)的毒素,因其独特结构显示出抗癌活性。
    • 待询
    规格
    数量
  • Mal-PEG4-VC-PAB-DMEA-duocarmycin-DM
    T205787
    Mal-PEG4-VC-PAB-DMEA-duocarmycin-DM 是一种硫醇反应型 Drug-linker,Duocarmycin DM 是一种 DNA 小沟烷基化剂,可作为 ADC 结合物毒素,用于抗体-药物偶联物(ADC)的合成。
    • 待询
    规格
    数量
  • G3-VC-PAB-DMEA-Duocarmycin DM
    T878642415664-00-3
    G3-VC-PAB-DMEA-Duocarmycin DM (Compound LD-1) 为一种以duocarmycin为基础的连接分子,主要应用于ADC制备。
    • 待询
    待询
    规格
    数量
  • MA-PEG4-VC-PAB-DMEA-duocarmycin DM
    T87846
    MA-PEG4-vc-PAB-DMEA-duocarmycin DM 是一种ADC药物连接物缀合物,由抗癌抗生素Duocarmycin DM 和 MA-PEG4-vc-PAB-DMEA连接而成。
    • 待询
    待询
    规格
    数量
  • Duocarmycin MB
    倍癌霉素 MB
    T111171613286-58-0
    Duocarmycin MB can be used against multi-drug resistant cell lines. Duocarmycin MB is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove.
    • ¥ 15000
    8-10周
    规格
    数量
  • Duocarmycin A (GMP)
    倍癌霉素 A (GMP)
    T15180-GMP118292-34-5
    Duocarmycin A (GMP)是 Duocarmycin A 的 GMP 级别试剂。Duocarmycin A 是一种抗肿瘤抗生素,属于 DNA 甲基化剂,能够有效地在 DNA 中富含腺嘌呤序列的 3' 端将腺嘌呤 N3 甲基化。作为一种化疗药物,杜卡霉素 A 会导致 HLC-2 细胞出现典型的凋亡变化。
      询价
    • Duocarmycin GA
      倍癌霉素 GA
      T111151613286-59-1
      Duocarmycin GA, an antibody drug conjugate (ADC) toxin and a DNA alkylating agent, effectively targets and binds in the minor groove of DNA. It is particularly potent against multi-drug resistant cell lines, offering a strategic approach in combating resistance.
      • 待询
      3-6月
      规格
      数量
    • MC-Val-Cit-PAB-duocarmycin chloride
      MC-Val-Cit-PAB-duocarmycin
      T183242055896-98-3
      MC-Val-Cit-PAB-duocarmycin is an antibody-drug conjugate (ADC) linker that combines duocarmycin, a potent DNA minor groove-binding alkylating agent, with an antitumor drug through the MC-Val-Cit-PAB linker, exhibiting significant antitumor activity.
      • 待询
      规格
      数量
    • (S)-Seco-Duocarmycin SA
      开环-倍癌霉素 Sa
      T12813152785-82-5
      (S)-Seco-Duocarmycin SA 是一种 DNA 烷化剂,也是具有高效抗肿瘤活性的抗生素,可用于合成 ADC 化合物。
      • ¥ 3570
      现货
      规格
      数量
    • Duocarmycin MA
      倍癌霉素 MA
      T111161613286-57-9
      Duocarmycin MA can be used against multi-drug resistant cell lines.Duocarmycin MA is an antibody drug conjugates (ADCs) toxin. Duocarmycin is a DNA alkylating agent that binds in the minor groove.
      • ¥ 13900
      8-10周
      规格
      数量
    • Seco-DUBA
      T386111227961-59-2
      Seco-DUBA, a duocarmycin (DUBA) prodrug, possess two hydroxyl groups suitable for antibody coupling through a linker. This compound, serving as a precursor, enables the synthesis of antibody-drug conjugates (ADCs).
      • ¥ 11000
      5日内发货
      规格
      数量