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Cat. No. | Product Name | Target | Signaling Pathways |
---|---|---|---|
T1907 |
Mdivi-1
Mitochondrial division inhibitor 1 |
Apoptosis; Mitophagy; Dynamin; Autophagy | Apoptosis; Autophagy; Cytoskeletal Signaling |
Mdivi-1 (Mitochondrial division inhibitor 1) 是一种线粒体分裂抑制剂,抑制 DRP1 和 Dynamin I (IC50=1-10 μM)。Mdivi-1 可以抑制线粒体自噬。 |
Cat. No. | Product Name | Species | Expression System |
---|---|---|---|
TMPH-01254 |
DNM1 Protein, Human, Recombinant (His)
DNM,Dynamin,Dynamin-1,DNM1 |
Human | E. coli |
Microtubule-associated force-producing protein involved in producing microtubule bundles and able to bind and hydrolyze GTP. Most probably involved in vesicular trafficking processes. Involved in receptor-mediated endocytosis. | |||
TMPH-01255 |
DNM1L Protein, Human, Recombinant (His & Myc)
Dynamin-like protein IV,Dynamin-related protein 1,D... |
Human | E. coli |
Functions in mitochondrial and peroxisomal division. Mediates membrane fission through oligomerization into membrane-associated tubular structures that wrap around the scission site to constrict and sever the mitochondrial membrane through a GTP hydrolysis-dependent mechanism. The specific recruitment at scission sites is mediated by membrane receptors like MFF, MIEF1 and MIEF2 for mitochondrial membranes. While the recruitment by the membrane receptors is GTP-dependent, the following hydrolysis... | |||
TMPJ-01406 |
MOB4 Protein, Human, Recombinant (His)
PREI3,MOBKL3,Mps One Binder Kinase Activator-Like 3,Mob1... |
Human | E. coli |
MOB-Like Protein Phocein is a member of the MOB1/Phocein Family. MOB-Like Protein Phocein is associated with membranes and the Golgi stacks. It is present in the cytosol, where it behaves as a protein complex. It has been shown that MOB-Like Protein Phocein interacts with DNM1, EPS15 and Nucleoside Diphosphate Kinase. MOB-Like Protein Phocein is the major partner of Striatin Family members and may play a important role in membrane trafficking, specifically in membrane budding reactions. | |||
TMPJ-01307 |
PACSIN1 Protein, Human, Recombinant (His)
Protein Kinase C and Casein Kinase Substrate in Neurons Prot... |
Human | Human Cells |
Protein Kinase C and Casein Kinase Substrate in Neurons Protein 1 (PACSIN1) belongs to the PACSIN family. PACSIN1 contains one FCH domain and one SH3 domain. PACSIN1 is highly expressed in the brain and at lower leves in the heart, pancreas, and liver. PACSIN1 may play a role in vesicle formation and transport. PACSIN1 has been shown to interact with DNM1, PACSIN3, Huntingtin, and PACSIN2. In addition, PACSIN1 is phosphorylated by casein kinase 2 (CK2) and protein kinase C (PKC). |