TDK-HCPT is a small molecule conjugate that links glutathione-sensitive thiamine disulfide with the chemotherapeutic agent 10-hydroxycamptothecin through a thioacetal bond. It targets tumor cells and prolongs the retention of the chemotherapeutic drug within these cells. TDK-HCPT inhibits tumor growth, induces apoptosis (apoptosis) in tumor cells, and exhibits antitumor activity.