Name: Spiramycin hexanedioate
Brand: TargetMol
SKU: TN8068
Rating: 4.5 (1 reviews)

规格

价格

库存

数量

10 mg

待询

50 mg

待询

生物活性

产品描述	Spiramycin hexanedioate (Rovamycin) is a macrolide antibiotic produced by Streptomyces ambofaciens, exhibiting antibacterial, anti-Toxoplasma, and antiparasitic properties. The structure of Spiramycin hexanedioate comprises 16 lactone rings and is adorned with three sugars: mycaminose, forosamine, and mycarose.
体外活性	Spiramycin 在处理感染T. gondii的HeLa细胞和未感染的HeLa细胞时(24小时;1-1000μM),不仅展示了减少细胞毒性的效果,还显示了抗Toxoplasma gondii的活性.其半数抑制浓度(IC 50)值分别为对于HeLa细胞为189 μM,对于T. gondii感染的HeLa细胞为262 μM.
体内活性	Spiramycin(100 mg/kg;腹腔注射;每日一次;连续4天;雌性KM小鼠)治疗可减少弓形虫的数量,并降低肝脏毒性,显著增强抗氧化作用.此外,斯皮拉霉素还能减轻肝脏中的肉芽肿炎症程度.
别名	Rovamycin hexanedioate

化学信息

CAS No.

11034-40-5

储存&溶解度

存储	Powder: -20°C for 3 years \| In solvent: -80°C for 1 year \| Shipping with blue ice/Shipping at ambient temperature.

Spiramycin hexanedioate